Evidence for distinct subcellular sites of opiate receptors. Demonstration of opiate receptors in smooth microsomal fractions isolated from rat brain.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Opiate Receptor: Demonstration in Nervous Tissue

1973 • 2,364 citations

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

1980 • 1,579 citations

Stereospecific Binding of the Potent Narcotic Analgesic [ ³ H]Etorphine to Rat-Brain Homogenate

1973 • 1,055 citations

Biochemistry of dystrophic muscle. Mitochondrial succinate-tetrazolium reductase and adenosine triphosphatase

1961 • 1,041 citations

A sensitive and specific assay for the estimation of monoamine oxidase

1963 • 992 citations

ENZYME-STRUCTURE RELATIONSHIPS IN THE ENDOPLASMIC RETICULUM OF RAT LIVER

1962 • 718 citations

Multiple opiate receptors. Enkephalins and morphine bind to receptors of different specificity.

1979 • 684 citations

Isolation of synaptic plasma membrane from brain by combined flotation-sedimentation density gradient centrifugation

1974 • 662 citations

Stereospecific Interaction Between Narcotic Analgesics and a Synaptic Plasma Membrane Fraction of Rat Cerebral Cortex

1973 • 650 citations

Synaptic plasma membranes from rat brain synaptosomes: Isolation and partial characterization

1971 • 634 citations

Opiate Receptor Binding of Agonists and Antagonists Affected Differentially by Sodium

1974 • 554 citations

Markers for Gene Expression in Cultured Cells from the Nervous System

1972 • 403 citations

ISOLATION AND PARTIAL CHARACTERIZATION OF RAT BRAIN SYNAPTIC PLASMA MEMBRANES¹

1974 • 340 citations

Opioid Receptors Undergo Axonal Flow

1980 • 274 citations

Improved rapidity and precision in the determination of brain 2′,3′-cyclic nucleotide 3′-phosphohydrolase

1973 • 244 citations

Immunocytochemical localization of enkephalin in the neostriatum of rat brain: A light and electron microscopic study

1980 • 241 citations

Multiple Neurotransmitter Receptors

1980 • 223 citations

Interaction of ligands with the opiate receptors of brain membranes: Regulation by ions and nucleotides

1978 • 216 citations

Presence of calmodulin in postsynaptic densities isolated from canine cerebral cortex.

1979 • 208 citations

Differential Regulation by Guanine Nucleotides of Opiate Agonist and Antagonist Receptor Interactions

1980 • 201 citations

Intracellular polypeptide hormone receptors. The demonstration of specific binding sites for insulin and human growth hormone in Golgi fractions isolated from the liver of female rats.

1978 • 196 citations

Synaptic localization of kainic acid binding sites

1981 • 195 citations

Naloxazone, a long-acting opiate antagonist: effects on analgesia in intact animals and on opiate receptor binding in vitro.

1980 • 170 citations

Stereospecific binding ofd-lysergic acid diethylamide (LSD) to brain membranes: Relationship to serotonin receptors

1975 • 166 citations

Newly synthesized acetylcholine receptors are located in the Golgi apparatus.

1978 • 160 citations

Guanine nucleotides differentiate agonist and antagonist interactions with opiate receptors

1978 • 143 citations

Localization of opiate receptor binding in synaptic membranes of rat brain

1974 • 131 citations

A morphine-like factor ‘enkephalin’ in rat brain: subcellular localization

1976 • 129 citations

Intracellular polypeptide hormone receptors. Characterization of insulin binding sites in Golgi fractions from the liver of female rats.

1978 • 123 citations

STUDIES ON SODIUM–POTASSIUM ADENOSINE TRIPHOSPHATASE OF THE NERVE ENDINGS AND APPEARANCE OF ELECTRICAL ACTIVITY IN DEVELOPING RAT BRAIN

1967 • 113 citations

Cell fractionation studies on the guinea pig pancreas. Redistribution of exocrine proteins during tissue homogenization.

1978 • 99 citations

Solubilization of a Stereospecific Opiate-Macromolecular Complex from Rat Brain

1975 • 88 citations

Acetylcholine receptor subunits transit a precursor pool before acquiring alpha-bungarotoxin binding activity.

1981 • 76 citations

Initial ultrastructural abnormalities at the motor end plate produced by a cholinesterase inhibitor

1977 • 61 citations

FINE STRUCTURAL LOCALIZATION OF ACETYLCHOLINESTERASE USING ACETYL-β-METHYLTHIOCHOLINE AND ACETYLSELENOCHOLINE AS SUBSTRATES

1969 • 51 citations

Characterization of gonadotropin binding sites in the intracellular organelles of bovine corpora lutea and comparison with plasma membrane sites.

1981 • 44 citations

GTP modulation of opiate receptors in regions of rat brain and possible mechanism of GTP action

1980 • 39 citations

Characterization, solubilization, and separation of two distinct dopamine receptors in canine caudate nucleus.

1980 • 39 citations

MULTIPLE DOPAMINE BINDING SITES: SUBCELLULAR LOCALIZATION AND BIOCHEMICAL CHARACTERIZATION¹

1979 • 34 citations

Fine structural localization of potassium-stimulated rho nitrophenylphosphatase activity in denrites of the cerebral cortex

1978 • 33 citations

Biochemical characterization of postsynaptically localized cyclic nucleotide phosphodiesterase

1979 • 31 citations

STUDIES ON NICOTINIC ACETYLCHOLINE RECEPTORS IN MAMMALIAN BRAIN. CHARACTERIZATION OF A MICROSOMAL SUBFRACTION ENRICHED IN RECEPTOR FUNCTION FOR DIFFERENT NEUROTRANSMITTERS

1978 • 30 citations

Distribution of stereospecific opiate receptor binding activity between subcellular fractions from ovine corpus striatum

1980 • 20 citations