Tyrosine phosphorylation and association of Syk with FcγRII in monocytic THP-1 cells

SH2 domains recognize specific phosphopeptide sequences

1993 • 2,685 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Fc Receptors

1991 • 1,220 citations

ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain

1992 • 1,037 citations

Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav.

1994 • 886 citations

Sequential Interactions of the TCR with Two Distinct Cytoplasmic Tyrosine Kinases

1994 • 711 citations

Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications

1993 • 706 citations

Tyrosine kinases Lyn and Syk regulate B cell receptor-coupled Ca2+ mobilization through distinct pathways.

1994 • 664 citations

T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases

1993 • 552 citations

Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis

1991 • 449 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

T cell activation by clustered tyrosine kinases

1993 • 379 citations

Differential control of the tyrosine kinases Lyn and Syk by the two signaling chains of the high affinity immunoglobulin E receptor.

1994 • 367 citations

Human monocytes and U937 cells bear two distinct Fc receptors for IgG.

1986 • 337 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain.

1993 • 318 citations

The B Cell Antigen Receptor Complex: Association of Ig-α and Ig-β with Distinct Cytoplasmic Effectors

1992 • 307 citations

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes.

1989 • 300 citations

Syk activation by the Src-family tyrosine kinase in the B cell receptor signaling.

1994 • 299 citations

Association of the 72-kDa protein-tyrosine kinase PTK72 with the B cell antigen receptor.

1992 • 298 citations

Tyrosine kinases and tyrosine-based activation motifs. Current research on activation via the T cell antigen receptor.

1992 • 287 citations

Signal transduction by immunoglobulin is mediated through Ig alpha and Ig beta.

1993 • 237 citations

Fc epsilon RI-mediated tyrosine phosphorylation and activation of the 72-kDa protein-tyrosine kinase, PTK72, in RBL-2H3 rat tumor mast cells.

1992 • 231 citations

Specific Motifs Recognized by the SH2 Domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav

1994 • 224 citations

Multichain immune recognition receptors: similarities in structure and signaling pathways

1992 • 210 citations

Physical and functional association of Src-related protein tyrosine kinases with Fc gamma RII in monocytic THP-1 cells.

1994 • 198 citations

Cross-linking of Fc gamma receptor I (Fc gamma RI) and receptor II (Fc gamma RII) on monocytic cells activates a signal transduction pathway common to both Fc receptors that involves the stimulation of p72 Syk protein tyrosine kinase.

1993 • 198 citations

Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain.

1992 • 184 citations

Association of the high-affinity receptor for IgG (Fc gamma RI) with the gamma subunit of the IgE receptor.

1993 • 176 citations

Activation of Fc gamma RII induces tyrosine phosphorylation of multiple proteins including Fc gamma RII.

1992 • 172 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

Regulation of Phagocytosis and [Ca ²⁺ ] _i Flux by Distinct Regions of an Fc Receptor

1991 • 150 citations

Tyrosine phosphorylation of phospholipase C-gamma 1 induced by cross-linking of the high-affinity or low-affinity Fc receptor for IgG in U937 cells.

1992 • 145 citations

Human Fc gamma RII, in the absence of other Fc gamma receptors, mediates a phagocytic signal.

1991 • 140 citations

Association of immunoglobulin G Fc receptor II with Src-like protein-tyrosine kinase Fgr in neutrophils.

1993 • 139 citations

Involvement of p72syk, a protein-tyrosine kinase, in Fc gamma receptor signaling

1993 • 137 citations

Stimulation of macrophage Fc gamma RIIIA activates the receptor-associated protein tyrosine kinase Syk and induces phosphorylation of multiple proteins including p95Vav and p62/GAP-associated protein.

1994 • 117 citations

Clustering of the high affinity Fc receptor for immunoglobulin G (Fc gamma RI) results in phosphorylation of its associated gamma-chain.

1994 • 93 citations

Stimulation of tyrosine phosphorylation and calcium mobilization by Fc gamma receptor cross-linking. Regulation by the phosphotyrosine phosphatase CD45.

1993 • 92 citations

Protein tyrosine phosphorylation induced via the IgG receptors Fc gamma Ri and Fc gamma RII in the human monocytic cell line THP-1.

1992 • 75 citations

Correlations among tyrosine phosphorylation of Shc, p72syk, PLC-gamma 1, and [Ca2+]i flux in Fc gamma RIIA signaling.

1994 • 59 citations

Tyrosine phosphorylation provides an obligatory early signal for Fc gamma RII-mediated endocytosis in the monocytic cell line THP-1.

1994 • 53 citations

Lineage-independent activation of immune system effector function by myeloid Fc receptors.

1992 • 48 citations