Therapeutic strategies with monoclonal antibodies and immunoconjugates.

RNA N-glycosidase activity of ricin A-chain. Mechanism of action of the toxic lectin ricin on eukaryotic ribosomes.

1987 • 943 citations

A Randomized Clinical Trial of OKT3 Monoclonal Antibody for Acute Rejection of Cadaveric Renal Transplants

1985 • 697 citations

Ganglioside GD2 specific monoclonal antibody 3F8: a phase I study in patients with neuroblastoma and malignant melanoma.

1987 • 404 citations

Monoclonal antibody 1F5 (anti-CD20) serotherapy of human B cell lymphomas

1987 • 360 citations

Acidification of the cytosol inhibits endocytosis from coated pits.

1987 • 345 citations

Redesigning Nature's Poisons to Create Anti-Tumor Reagents

1987 • 329 citations

Human monoclonal antibody production

1987 • 224 citations

Dosimetric aspects of radiolabeled antibodies for tumor therapy.

1986 • 216 citations

Therapy of patients with malignant melanoma using a monoclonal antimelanoma antibody-ricin A chain immunotoxin.

1987 • 212 citations

Anti-idiotype immunization of cancer patients: modulation of the immune response.

1987 • 190 citations

ANTI-IDIOTYPIC AND NON-ANTI-INDIOTYPIC ANTIBODIES TO OKT3 ARISING DESPITE INTENSE IMMUNOSUPPRESSION

1986 • 190 citations

Tolerance to rat monoclonal antibodies. Implications for serotherapy.

1986 • 161 citations

Phase II clinical trial of a murine monoclonal antibody cytotoxic for gastrointestinal adenocarcinoma.

1985 • 134 citations

Phase I Trial of Multiple Large Doses of Murine Monoclonal Antibody CO17-1A. II. Pharmacokinetics and Immune Response1

1988 • 122 citations

The characteristics of blood-borne radiolabels and the effect of anti-mouse IgG antibodies on localization of radiolabeled monoclonal antibody in cancer patients.

1985 • 119 citations

Study of the plasma clearance of antibody – ricin‐A‐chain immunotoxins

1986 • 116 citations

Purification of ricin A1, A2, and B chains and characterization of their toxicity.

1986 • 102 citations

Lack of radioimmunodetection and complications associated with monoclonal anticarcinoembryonic antigen antibody cross-reactivity with an antigen on circulating cells.

1984 • 90 citations

Limitations to the killing of tumours using radiolabelled antibodies

1987 • 83 citations

Studies on B lymphoid tumors treated with monoclonal anti-idiotype antibodies: correlation with clinical responses

1987 • 79 citations

Antitumor activity of intraperitoneal immunotoxins in a nude mouse model of human malignant mesothelioma.

1987 • 67 citations

Endocytosis and degradation of murine anti-human CD3 monoclonal antibodies by normal and malignant T-lymphocytes.

1988 • 66 citations

REEXPOSURE TO OKT3 IN RENAL ALLOGRAFT RECIPIENTS

1988 • 65 citations

Characterization of a mouse/human chimeric monoclonal antibody (17-1A) to a colon cancer tumor-associated antigen.

1987 • 64 citations

An improved synthesis of a methotrexate-albumin-791T/36 monoclonal antibody conjugate cytotoxic to human osteogenic sarcoma cell lines.

1986 • 62 citations

Antitumor activity of an immunotoxin in a nude mouse model of human ovarian cancer.

1987 • 60 citations

Induction of specific immunity to human colon carcinoma by anti‐idiotypic antibodies to monoclonal antibody CO17‐1A

1987 • 51 citations

Construction and characterisation of a hybrid-hybrid monoclonal antibody recognising both carcinoembryonic antigen (CEA) and vinca alkaloids

1987 • 45 citations

Epstein Barr virus binding induces internalization of the C3d receptor: a novel immunotoxin delivery system.

1986 • 43 citations

Immune Interventions in Disease

1987 • 40 citations

Uptake of native and deglycosylated ricin A-chain immunotoxins by mouse liver parenchymal and non-parenchymal cells in vitro and in vivo

1988 • 40 citations

Anti-human tumor antibodies induced in mice and rabbits by "internal image" anti-idiotypic monoclonal immunoglobulins.

1987 • 38 citations

Increased therapeutic effect of vinca alkaloids targeted to tumour by a hybrid-hybrid monoclonal antibody

1987 • 33 citations

Biodistribution of ricin toxin A chain-monoclonal antibody 791T/36 immunotoxin and influence of hepatic blocking agents.

1987 • 30 citations

Nature of linkage and mode of action of methotrexate conjugated with antitumor antibodies: implications for future preparation of conjugates.

1988 • 30 citations

Selective Killing of Normal and Neoplastic Human B Cells with Anti-CD 19- and Anti-CD22-Ricin A Chain Immunotoxins

1986 • 29 citations

The implications of patient antibody response for the clinical usefulness of immunoscintigraphy

1984 • 28 citations

Correction: Potentiation of Anti-Carcinoembryonic Antigen Immunotoxin Cytotoxicity by Monoclonal Antibodies Reacting with Co-Expressed Carcinoembryonic Antigen Epitopes

2013 • 27 citations

Human monoclonal antibodies and monoclonal antibody multispecificity

1987 • 20 citations

Anti-idiotypic antibodies and the induction of specific tumor immunity

1987 • 20 citations

Do Primary Physicians Actually Manage Their Patients' Fee-for-Service Care?

1988 • 19 citations

Monoclonal antibodies and immunoconjugates for cancer treatment.

1987 • 13 citations

Comparative biodistribution of methotrexate and monoclonal antibody-methotrexate complexes in mice

1987 • 6 citations