Alternative Cytokines in the Immunoregulation of the Human B Cell Cycle

An endotoxin-induced serum factor that causes necrosis of tumors.

1975 • 4,522 citations

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

1976 • 2,458 citations

Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin

1984 • 1,738 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Characterization of receptors for human tumour necrosis factor and their regulation by γ-interferon

1985 • 896 citations

Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes.

1986 • 777 citations

The transforming growth factor-β system, a complex pattern of cross-reactive ligands and receptors

1987 • 710 citations

Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity

1984 • 638 citations

B-Cell Stimulatory Factor-1/Interleukin 4

1987 • 602 citations

Novel Interleukin-2 Receptor Subunit Detected by Cross-Linking Under High-Affinity Conditions

1986 • 585 citations

Effects of transforming growth factor beta on the functions of natural killer cells: depressed cytolytic activity and blunting of interferon responsiveness.

1986 • 579 citations

Interleukin 2 high-affinity receptor expression requires two distinct binding proteins.

1987 • 565 citations

Inhibition of cytotoxic T cell development by transforming growth factor beta and reversal by recombinant tumor necrosis factor alpha.

1987 • 497 citations

Demonstration of a non-Tac peptide that binds interleukin 2: a potential participant in a multichain interleukin 2 receptor complex.

1986 • 477 citations

Purification and initial characterization of a type beta transforming growth factor from human placenta.

1983 • 409 citations

Conversion of a high molecular weight latent β-TGF from chicken embryo fibroblasts into a low molecular weight active β-TGF under acidic conditions

1985 • 366 citations

Expression of Tac antigen on activated normal human B cells.

1984 • 355 citations

Purification and properties of a type .beta. transforming growth factor from bovine kidney

1983 • 355 citations

Cartilage-inducing factor-B is a unique protein structurally and functionally related to transforming growth factor-beta.

1987 • 336 citations

Normal embryo fibroblasts release transforming growth factors in a latent form

1984 • 336 citations

A second human interleukin-2 binding protein that may be a component of high-affinity interleukin-2 receptors

1987 • 306 citations

Transforming Growth Factor β

1988 • 295 citations

Transforming growth factors from neoplastic and nonneoplastic tissues.

1983 • 288 citations

Interleukin 2 binding molecule distinct from the Tac protein: analysis of its role in formation of high-affinity receptors.

1987 • 252 citations

Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function.

1985 • 249 citations

Effect of tumor necrosis factor alpha on mitogen-activated human B cells.

1987 • 245 citations

Direct activation of human resting T cells by IL 2: the role of an IL 2 receptor distinct from the Tac protein.

1987 • 179 citations

Lymphotoxin Is an Important T Cell-Derived Growth Factor for Human B Cells

1987 • 151 citations

Beta transforming growth factors are potential regulators of B lymphopoiesis.

1987 • 145 citations

Stimulation of immunoglobulin secretion in human B lymphocytes as a direct effect of high concentrations of IL 2.

1984 • 143 citations

Proliferative responses of normal human B lymphocytes. Development of an assay system for human B cell growth factor (BCGF).

1982 • 142 citations

Latent beta-transforming growth factor in nontransformed and Kirsten sarcoma virus-transformed normal rat kidney cells, clone 49F.

1984 • 112 citations

Quantification and characterization of high‐affinity membrane receptors for tumor necrosis factor on human leukemic cell lines

1986 • 110 citations

Development of a human T-T cell hybridoma secreting B cell growth factor.

1983 • 104 citations

Macrophage Factor Controlling Differentiation of B Cells

1979 • 98 citations

Purification to homogeneity of a high molecular weight human B cell growth factor; demonstration of specific binding to activated B cells; and development of a monoclonal antibody to the factor.

1985 • 88 citations

A high molecular weight component of the human tumor necrosis factor receptor is associated with cytotoxicity.

1987 • 85 citations

Direct effects of a monoclonal B cell differentiation factor and of purified interleukin 1 on B cell differentiation.

1984 • 60 citations

Epstein‐Barr virus mediates a switch in responsiveness to transforming growth factor, type beta, in cells of the B cell lineage

1987 • 55 citations

Direct effect of interleukin 2 on the differentiation of human B cells which have not been preactivated in vitro

1985 • 50 citations

Serum containing endotoxin-induced tumour necrosis factor substitutes for helper T cells

1976 • 33 citations

Delineation of Human B Cell Differentiation: Immunological and Molecular Characterization of Human B Cell Differentiation Factor (BSF-2)

1987 • 5 citations