Spindle Structure and the Mechanisms of Chromosome Movement

Microtubule assembly nucleated by isolated centrosomes

1984 • 775 citations

Molecules and Cell Movement

1977 • 767 citations

Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae

1975 • 617 citations

Opposite end assembly and disassembly of microtubules at steady state in vitro

1978 • 567 citations

Arrangement of subunits in flagellar microtubules

1974 • 501 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Model for Mitosis

1969 • 370 citations

CHROMOSOME MICROMANIPULATION

1969 • 367 citations

Cell division and the mitotic spindle.

1981 • 323 citations

Spindle microtubule dynamics in sea urchin embryos: analysis using a fluorescein-labeled tubulin and measurements of fluorescence redistribution after laser photobleaching.

1984 • 291 citations

Electron-microscopic study of the spindle and chromosome movement in the yeast Saccharomyces Cerevisiae

1976 • 280 citations

Structural polarity and directional growth of microtubules of Chlamydomonas flagella

1974 • 249 citations

Organization and Function of the Mitotic Spindle

1964 • 241 citations

The structure of the cold-stable kinetochore fiber in metaphase PtK1 cells

1981 • 233 citations

Centrosomes and mitotic poles

1984 • 229 citations

Role of tubulin-associated proteins in microtubule nucleation and elongation

1977 • 225 citations

Influence of the centrosome on the structure of nucleated microtubules.

1985 • 221 citations

Initiation and growth of microtubules from mitotic centers in lysed mammalian cells.

1975 • 219 citations

Structural polarity of kinetochore microtubules in PtK1 cells.

1981 • 218 citations

Spindle dynamics and chromosome movements

1972 • 217 citations

Visualization of the structural polarity of microtubules

1980 • 213 citations

Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus.

1979 • 195 citations

Rethinking mitosis

1982 • 195 citations

THE DISTRIBUTION OF SPINDLE MICROTUBULES DURING MITOSIS IN CULTURED HUMAN CELLS

1971 • 192 citations

Microtubule-nucleating activity of centrosomes in Chinese hamster ovary cells is independent of the centriole cycle but coupled to the mitotic cycle.

1981 • 191 citations

Polarity of midbody and phragmoplast microtubules.

1980 • 184 citations

ULTRASTRUCTURAL ANALYSIS OF MITOTIC SPINDLE ELONGATION IN MAMMALIAN CELLS IN VITRO

1971 • 184 citations

Mechanics of chromosome separation during mitosis in Fusarium (Fungi imperfecti): new evidence from ultrastructural and laser microbeam experiments.

1981 • 169 citations

Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin.

1975 • 164 citations

Interference of GTP hydrolysis in the mechanism of microtubule assembly: an experimental study.

1984 • 160 citations

Polarity of microtubules nucleated by centrosomes and chromosomes of Chinese hamster ovary cells in vitro

1980 • 155 citations

Nuclear Division in the Fungi

1979 • 154 citations

Tubulin assembly sites and the organization of cytoplasmic microtubules in cultured mammalian cells.

1981 • 154 citations

Functional autonomy of monopolar spindle and evidence for oscillatory movement in mitosis.

1982 • 145 citations

Rapid rate of tubulin dissociation from microtubules in the mitotic spindle in vivo measured by blocking polymerization with colchicine.

1984 • 142 citations

Chromosome behavior after laser microirradiation of a single kinetochore in mitotic PtK2 cells.

1981 • 137 citations

Assembly of microtubules onto kinetochores of isolated mitotic chromosomes of HeLa cells.

1975 • 137 citations

Decoration of spindle microtubules with Dynein: evidence for uniform polarity.

1981 • 126 citations

Tubulin hooks as probes for microtubule polarity: an analysis of the method and an evaluation of data on microtubule polarity in the mitotic spindle.

1984 • 123 citations

Origin of kinetochore microtubules in Chinese hamster ovary cells

1980 • 119 citations

Characteristics of the polar assembly and disassembly of microtubules observed in vitro by darkfield light microscopy.

1979 • 116 citations

Traction force on a kinetochore at metaphase acts as a linear function of kinetochore fiber length

1982 • 110 citations

Cell division in two large pennate diatoms Hantzschia and Nitzschia III. A new proposal for kinetochore function during prometaphase.

1980 • 105 citations

Polarity of spindle microtubules in Haemanthus endosperm.

1982 • 102 citations

Structure of the tubulin dimer in zinc-induced sheets

1978 • 101 citations

Experimental separation of pronuclei in fertilized sea urchin eggs: chromosomes do not organize a spindle in the absence of centrosomes.

1985 • 100 citations

Structure and physiology of the mammalian mitotic spindle.

1975 • 100 citations

Cross-sectional structure of the central mitotic spindle of Diatoma vulgare. Evidence for specific interactions between antiparallel microtubules.

1979 • 98 citations

Phase changes at the end of a microtubule with a GTP cap.

1984 • 96 citations

Direct visualization of fluorescein-labeled microtubules in vitro and in microinjected fibroblasts.

1981 • 96 citations

A Functional Mitotic Spindle Prepared from Mammalian Cells in Culture

1974 • 89 citations

Architecture of the microtubule component of mitotic spindles from Dictyostelium discoideum

1985 • 86 citations

Three-dimensional structure of the central mitotic spindle of Diatoma vulgare.

1979 • 86 citations

Mitosis in the pinnate diatom surirella ovalis

1977 • 86 citations

Ultraviolet microbeam irradiations of mitotic diatoms: investigation of spindle elongation.

1983 • 85 citations

Recurrent pole-to-pole movements of the sex chromosome during prometaphase I in Melanoplus differentials spermatocytes

1961 • 82 citations

Dynamics of spindle microtubule organization: kinetochore fiber microtubules of plant endosperm.

1982 • 73 citations

A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells.

1981 • 73 citations

Nucleated assembly of mitotic microtubules in living PTK₂ cells after release from nocodazole treatment

1981 • 73 citations

A microtubule-associated protein antigen unique to mitotic spindle microtubules in PtK1 cells.

1983 • 71 citations

Meiosis in Drosophila melanogaster

1981 • 71 citations

Meiosis in Drosophila melanogaster. II. The prometaphase-I kinetochore microtubule bundle and kinetochore orientation in males.

1982 • 71 citations

Cooperation of kinetochores and pole in the establishment of monopolar mitotic apparatus.

1981 • 65 citations

CONSIDERATIONS ON SOME ELEMENTARY FEATURES OF MITOSIS

2010 • 62 citations

HYDROSTATIC PRESSURE EFFECTS UPON THE SPINDLE FIGURE AND CHROMOSOME MOVEMENT. II. EXPERIMENTS ON THE MEIOTIC DIVISIONS OF TRADESCANTIA POLLEN MOTHER CELLS

1946 • 62 citations

Analysis of the distribution of spindle microtubules in the diatom Fragilaria.

1978 • 59 citations

Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching.

1984 • 58 citations

Pressure-induced depolymerization of spindle microtubules. II. Thermodynamics of in vivo spindle assembly.

1975 • 56 citations

The attachment of kinetochores to the pro-metaphase spindle in PtK1 cells

1981 • 56 citations

Microinjection of fluorescent tubulin into dividing sea urchin cells.

1983 • 54 citations

Structure of kinetochore fibers: Microtubule continuity and inter-microtubule bridges

1981 • 54 citations

Activity and stability of centrosomes in chinese hamster ovary cells in nucleation of microtubules in vitro

1984 • 52 citations

Organization of spindle microtubules in Ochromonas danica.

1980 • 45 citations

Mitosis in Oedogonium: spindle microfilaments and the origin of the kinetochore fiber.

1980 • 44 citations

Kinetics and Steady State Dynamics of Tubulin Addition and Loss at Opposite Microtubule Ends: The Mechanism of Action of Colchicinea

1986 • 42 citations

Kinetochore microtubule numbers of different sized chromosomes

1979 • 39 citations

Light and electron microscopic observations on cell division in two large pennate diatoms, Hantzschia and Nitzschia. I. Mitosis in vivo.

1980 • 37 citations

Primitive motile systems

1964 • 36 citations

Verteilung der Mikrotubuli in Metaphase- und Anaphase-Spindeln der Spermatocyten von Pales ferruginea

1973 • 36 citations

Functions of Flagellate and Other Centrioles in Cell Reproduction

1963 • 30 citations

Microtubule nucleation by the isolated microtubule-organizing centre of Physarum polycephalum myxamoebae

1982 • 30 citations

Polarity of kinetochore microtubules in Chinese hamster ovary cells after recovery from a colcemid block.

1983 • 27 citations

The organization of microtubules during anaphase and telophase spindle elongation in the rust fungus Puccinia.

1984 • 25 citations

Membrane distribution in dividing endosperm cells of Haemanthus.

1982 • 23 citations

An analysis of spindle ultrastructure during anaphase of micronuclear division in Tetrahymena

1980 • 23 citations

Directionally controlled spindle disassembly after mitosis in the diatom Pinnularia.

1982 • 22 citations

Microtubule Polarity and Interaction in Mitotic Spindle Function

1981 • 20 citations

Dynein-Microtubule Interactions: ATP-sensitive Dynein Binding and the Structural Polarity of Mitotic Microtubules

1982 • 18 citations

Near-neighbor analysis of spindle microtubules in the alga Ochromonas.

1983 • 16 citations

Dynamic changes in autosomal spindle fibers during prometaphase in crane fly spermatocytes

1982 • 12 citations

Bivalent behavior in Drosophila melanogaster males containing the In(1)sc 4Lsc8RX chromosome

1984 • 10 citations

Deleted Work

1955 • 0 citations