Chapter 11 Fusion Activity of the Hemagglutinin of Influenza Virus

Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 Å resolution

1981 • 2,490 citations

Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

1981 • 1,603 citations

Use of Helical Wheels to Represent the Structures of Proteins and to Identify Segments with Helical Potential

1967 • 1,178 citations

Expression of wild-type and mutant forms of influenza hemagglutinin: The role of folding in intracellular transport

1986 • 879 citations

Activation of influenza A viruses by trypsin treatment

1975 • 831 citations

Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.

1982 • 722 citations

Membrane fusion proteins of enveloped animal viruses

1983 • 670 citations

Infectious entry pathway of influenza virus in a canine kidney cell line.

1981 • 669 citations

Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

1975 • 602 citations

Cell fusion by Semliki Forest, influenza, and vesicular stomatitis viruses.

1981 • 569 citations

Amphiphilic Secondary Structure: Design of Peptide Hormones

1984 • 541 citations

The Agglutination of Red Cells by Allantoic Fluid of Chick Embryos Infected with Influenza Virus

1941 • 535 citations

Differences in antigen presentation to MHC class I-and class II-restricted influenza virus-specific cytolytic T lymphocyte clones.

1986 • 513 citations

Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation

1983 • 504 citations

Assembly of influenza hemagglutinin trimers and its role in intracellular transport.

1986 • 413 citations

Fusion mutants of the influenza virus hemagglutinin glycoprotein

1985 • 399 citations

Pathway of vesicular stomatitis virus entry leading to infection

1982 • 375 citations

Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of the Fl or HA2 viral polypeptides

1980 • 357 citations

Crystalline Antigen from the Influenza Virus Envelope

1972 • 346 citations

Membrane fusion activity of the influenza virus hemagglutinin. The low pH-induced conformational change.

1985 • 341 citations

Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus.

1986 • 334 citations

Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin?

1984 • 326 citations

Cloning and DNA sequence of double-stranded copies of haemagglutinin genes from H2 and H3 strains elucidates antigenic shift and drift in human influenza virus

1980 • 308 citations

Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation.

1978 • 283 citations

Membrane fusion activity of influenza virus.

1982 • 282 citations

Anti-peptide antibodies detect steps in a protein conformational change: low-pH activation of the influenza virus hemagglutinin.

1987 • 280 citations

Influenza viruses cause hemolysis and fusion of cells

1981 • 279 citations

Studies on the primary structure of the influenza virus hemagglutinin.

1975 • 261 citations

Activation of influenza virus by acidic media causes hemolysis and fusion of erythrocytes

1980 • 249 citations

Sorting of an apical plasma membrane glycoprotein occurs before it reaches the cell surface in cultured epithelial cells.

1984 • 247 citations

Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein

1982 • 236 citations

Cell-surface expression of influenza haemagglutinin from a cloned DNA copy of the RNA gene

1981 • 230 citations

Haemagglutinin of influenza virus expressed from a cloned gene promotes membrane fusion

1982 • 228 citations

Fusion of Semliki forest virus with the plasma membrane can be induced by low pH.

1980 • 202 citations

Structural studies on the protein subunits from three strains of influenza virus

1964 • 199 citations

Identification in a recombinant influenza virus of structural proteins derived from both parents

1966 • 195 citations

Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavage

1981 • 178 citations

Genetics of Influenza Viruses

1983 • 175 citations

Separation of two polypeptide chains from the hemagglutinin subunit of influenza virus

1971 • 175 citations

Interaction of influenza virus hemagglutinin with target membrane lipids is a key step in virus-induced hemolysis and fusion at pH 5.2.

1981 • 173 citations

Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport.

1985 • 145 citations

Monensin inhibits Semliki Forest virus penetration into culture cells.

1982 • 143 citations

The Influenza Virus RNA Segments and Their Encoded Proteins

1983 • 120 citations

Evidence from studies with a cross-linking reagent that the haemagglutinin of influenza virus is a trimer

1977 • 114 citations

An efficient method for introducing macromolecules into living cells.

1985 • 114 citations

STRUCTURE OF THE HAEMAGGLUTININ OF INFLUENZA VIRUS

1979 • 112 citations

Characterization of neuraminidases from myxoviruses

1966 • 110 citations

Analysis of progressive deletions of the transmembrane and cytoplasmic domains of influenza hemagglutinin.

1986 • 108 citations

Studies on the adaptation of influenza viruses to MDCK cells.

1984 • 107 citations

Variant influenza virus hemagglutinin that induces fusion at elevated pH

1986 • 107 citations

Antihistaminics, local anesthetics, and other amines as antiviral agents.

1981 • 104 citations

The structure of influenza viruses

1963 • 103 citations

Genetic Variation Among Influenza Viruses

1981 • 102 citations

Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin.

1985 • 98 citations

Selection of antigenic mutants of influenza viruses. Isolation and peptide mapping of their hemagglutinating proteins

1968 • 97 citations

Isolation and characterization of temperature-sensitive mutants of fowl plague virus

1975 • 96 citations

Structure of the Influenza Virus Hemagglutinin

1981 • 95 citations

ECOLOGY OF INFLUENZA VIRUSES IN LOWER MAMMALS AND BIRDS

1979 • 77 citations

Fusion and Haemolysis of Erythrocytes caused by Three Togaviruses: Semliki Forest, Sindbis and Rubella

1980 • 76 citations

Uncoating of enveloped viruses

1982 • 69 citations

The Polypeptides of Influenza Viruses

1973 • 62 citations

Processing of viral antigens and presentation to class II-restricted T cells

1986 • 46 citations

Inhibition of proteolytic cleavage of the hemagglutinin of influenza virus by the calcium-specific ionophore A23187.

1984 • 46 citations

Monoclonal antibodies detect different forms of influenza virus hemagglutinin during viral penetration and biosynthesis

1985 • 36 citations

Temperature-sensitive mutants of influenza virus: A mutation in the hemagglutinin gene

1976 • 34 citations

Studies on the Mechanism of Membrane Fusion

1973 • 23 citations

Virus-Determined Differences in the Pathogenesis of Influenza Virus Infections

1983 • 18 citations

PROCESSING OF THE HEMAGGLUTININ

1981 • 11 citations

Expression of Proteins on the Cell Surface Using Mammalian Vectors

1983 • 1 citations