Proteolytic activation of the influenza virus hemagglutinin: The structure of the cleavage site and the enzymes involved in cleavage

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

The Preparation and Enzymatic Hydrolysis of Reduced and S-Carboxymethylated Proteins

1963 • 2,600 citations

Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor

1979 • 1,758 citations

Strategy and tactics in protein chemistry

1970 • 1,226 citations

Activation of influenza A viruses by trypsin treatment

1975 • 831 citations

Amino-terminal Sequence Analysis of Proteins Purified on a Nanomole Scale by Gel Electrophoresis

1972 • 651 citations

Enhancement of the infectivity of influenza A and B viruses by proteolytic cleavage of the hemagglutinin polypeptide

1975 • 602 citations

Nucleotide sequence of cDNA coding for Semliki Forest virus membrane glycoproteins

1980 • 428 citations

Specific inhibition of paramyxovirus and myxovirus replication by oligopeptides with amino acid sequences similar to those at the N-termini of the Fl or HA2 viral polypeptides

1980 • 357 citations

Influenza virus proteins

1970 • 341 citations

Proteolytic cleavage of influenza virus hemagglutinins: primary structure of the connecting peptide between HA1 and HA2 determines proteolytic cleavability and pathogenicity of avian influenza viruses

1981 • 331 citations

The structure of the hemagglutinin, a determinant for the pathogenicity of influenza viruses

1979 • 298 citations

Complete nucleotide sequence of an influenza virus haemagglutinin gene from cloned DNA

1979 • 292 citations

Purification of the fusion protein of Sendai virus: analysis of the NH2-terminal sequence generated during precursor activation.

1978 • 283 citations

Influenza viruses cause hemolysis and fusion of cells

1981 • 279 citations

Studies on the primary structure of the influenza virus hemagglutinin.

1975 • 261 citations

Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA

1980 • 225 citations

ISOLATION OF TWO " BIG GASTRINS " FROM ZOLLINGER-ELLISON TUMOUR TISSUE

1972 • 213 citations

Studies on the Conversion of Proinsulin to Insulin

1973 • 168 citations

Isolation of a Glucagon-containing Peptide: Primary Structure of a Possible Fragment of Proglucagon

1973 • 165 citations

Proteolytic cleavage by plasmin of the HA polypeptide of influenza virus: Host cell activation of serum plasminogen

1973 • 163 citations

Fusion between cell membrane and liposomes containing the glycoproteins of influenza virus

1980 • 129 citations

On the structure of the influenza virus envelope

1972 • 126 citations

Proteolytic cleavage of the hemagglutinin polypeptide of influenza virus. Function of the uncleaved polypeptide HA

1973 • 125 citations

Complete sequence analysis shows that the hemagglutinins of the H0 and H2 subtypes of human influenza virus are closely related

1981 • 115 citations

STRUCTURE OF THE HAEMAGGLUTININ OF INFLUENZA VIRUS

1979 • 112 citations

Amino acid sequence changes in the haemagglutinin of A/Hong Kong (H3N2) influenza virus during the period 1968–77

1980 • 107 citations

Cleavability of hemagglutinin determines spread of avian influenza viruses in the chorioallantoic membrane of chicken embryo

1980 • 90 citations

Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins

1980 • 76 citations

Further Studies on the Activation of Influenza Virus by Proteolytic Cleavage of the Haemagglutinin

1977 • 76 citations

Structural analysis of human proparathyroid hormone by a new microsequencing approach

1974 • 67 citations

Changes in conformation and charge paralleling proteolytic activation of Newcastle disease virus glycoproteins

1981 • 67 citations

Enzymic processing of proparathyroid hormone by cell-free extracts of parathyroid glands

1977 • 62 citations

Influenza virus proteins: identity, synthesis, and modification analyzed by two-dimensional gel electrophoresis.

1978 • 58 citations

PRIMARY STRUCTURE OF THE HONG KONG (H3) HAEMAGGLUTININ

1979 • 53 citations

The Carboxyl‐Terminal Sequence of the Heavy Chain of a Hong Kong Influenza Haemagglutinin

1978 • 23 citations

The conformation of influenza virus haemagglutinin

1977 • 23 citations

Isoelectric focusing of viral polypeptides in urea

1978 • 22 citations

PROCESSING AND STRUCTURE OF MURINE LEUKEMIA VIRUS gag AND env GENE ENCODED POLYPROTEINS

1980 • 18 citations

PROCESSING OF THE INFLUENZA VIRUS HEMAGGLUTININ

1980 • 10 citations