Different migration patterns of antigen-presenting cells correlate with Th1/Th2-type responses in mice.

TH1 and TH2 Cells: Different Patterns of Lymphokine Secretion Lead to Different Functional Properties

1989 • 7,558 citations

Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

1986 • 7,504 citations

IL-10 inhibits cytokine production by activated macrophages.

1991 • 2,919 citations

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

1989 • 2,771 citations

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

1987 • 1,060 citations

Two types of murine helper T cell clone. II. Delayed-type hypersensitivity is mediated by TH1 clones.

1987 • 966 citations

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

1988 • 845 citations

Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.

1988 • 389 citations

Biological properties of interleukin 10

1992 • 359 citations

Role of Cytokines in the Differentiation of CD4⁺ T‐Cell Subsets in vivo

1991 • 289 citations

Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

1989 • 271 citations

Differential effect of IL-10 on dendritic cell-induced T cell proliferation and IFN-gamma production.

1993 • 251 citations

The Relationship Between Humoral and Cell‐Mediated Immunity

1972 • 228 citations

Migration patterns of dendritic cells in the mouse. Homing to T cell-dependent areas of spleen, and binding within marginal zone.

1988 • 226 citations

[33] First-strand cDNA synthesis primed with oligo(dT)

1987 • 220 citations

Cloned, Ia-restricted T cells that do not produce interleukin 4(IL 4)/B cell stimulatory factor 1(BSF-1) fail to help antigen-specific B cells.

1987 • 209 citations

Heterogeneity of helper/inducer T lymphocytes. II. Effects of interleukin 4- and interleukin 2-producing T cell clones on resting B lymphocytes.

1988 • 198 citations

Antigen-specific activation of effector macrophages by IFN-gamma producing (TH1) T cell clones. Failure of IL-4-producing (TH2) T cell clones to activate effector function in macrophages.

1989 • 183 citations

Stigma Variations: Observations on Suppressor T Cells and Leprosy

1992 • 155 citations

Heterogeneity of helper/inducer T lymphocytes. III. Responses of IL-2- and IL-4-producing (Th1 and Th2) clones to antigens presented by different accessory cells.

1990 • 144 citations

Mechanisms of regulation of cell-mediated immune responses. I. Effect of the route of immunization with TNP-coupled syngeneic cells on the induction and suppression of contact sensitivity to picryl chloride.

1978 • 136 citations

Interleukin-10 and its receptor.

1994 • 102 citations

Chemically modified antigen preferentially elicits induction of Th1-like cytokine synthesis patterns in vivo.

1993 • 98 citations

Interleukin 10

1991 • 87 citations

IL-4 synthesis by in vivo primed keyhole limpet hemocyanin-specific CD4+ T cells. I. Influence of antigen concentration and antigen-presenting cell type.

1992 • 69 citations

Role of IL-10 on antigen-presenting cell function for schistosomal egg-specific monoclonal T helper cell responses in vitro and in vivo.

1993 • 52 citations

Interleukin-4 may contribute to the abundant T-cell reaction and paucity of neoplastic B cells in T-cell-rich B-cell lymphomas.

1992 • 47 citations

The Role of Antigen-Presenting Cells in the Regulation of Delayed-Type Hypersensitivity

1993 • 40 citations

Conjugation of interferon-gamma to antigen enhances its adjuvanticity.

1990 • 39 citations

Cell-mediated and humoral immune responses in mice. III. Dynamic balance between delayed-type hypersensitivity and antibody response.

1977 • 36 citations

Differential activation of murine TH1 and TH2 clones

1991 • 33 citations

The role of antigen-presenting cells in the regulation of delayed-type hypersensitivity. I. Spleen dendritic cells.

1992 • 24 citations

Demonstration of T15 idiotype‐positive effector and suppressor T cells for phosphorylcholine‐specific delayed‐type hypersensitivity response in CBA/N or (CBA/N X BALB/c)F₁ male mice

1981 • 13 citations

The role of antibodies in the regulation of delayed-type hypersensitivity.

1991 • 9 citations

B-cell-mediated regulation of delayed-type hypersensitivity

1990 • 9 citations

Immunoregulatory Effect of Antibody on Delayed-Type Hypersensitivity in Mice

1989 • 9 citations