Genome Reorganization in Tetrahymena

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Somatic generation of antibody diversity

1983 • 3,275 citations

Separation of yeast chromosome-sized DNAs by pulsed field gradient gel electrophoresis

1984 • 2,847 citations

Animal cytology and evolution

1980 • 2,302 citations

The Cell in Development and Heredity

1925 • 1,750 citations

The Developmental Capacity of Nuclei taken from Intestinal Epithelium Cells of Feeding Tadpoles

1962 • 1,020 citations

A tandemly repeated sequence at the termini of the extrachromosomal ribosomal RNA genes in Tetrahymena

1978 • 1,003 citations

Separation of chromosomal DNA molecules from yeast by orthogonal-field-alternation gel electrophoresis

1984 • 887 citations

Specific Gene Amplification in Oocytes

1968 • 811 citations

An electrophoretic karyotype for yeast.

1985 • 787 citations

The Cell in Development and Heredity

1925 • 767 citations

Cloning yeast telomeres on linear plasmid vectors

1982 • 625 citations

The Cell Nucleus

1966 • 522 citations

All gene-sized DNA molecules in four species of hypotrichs have the same terminal sequence and an unusual 3' terminus.

1981 • 477 citations

Eucaryotic DNA: Organization of the genome for replication

1978 • 476 citations

The molecular basis of antibody formation: a paradox.

1965 • 394 citations

Differential synthesis of the genes for ribosomal RNA during amphibian oögenesis.

1968 • 386 citations

The control of gene expression in animal development

1974 • 369 citations

Inhibition of ColE1 RNA primer formation by a plasmid-specified small RNA.

1981 • 362 citations

Control of cole 1 plasmid replication: The process of binding of RNA I to the primer transcript

1984 • 298 citations

The control of gene expression in animal development

1974 • 292 citations

New Techniques for Purifying Large DNAs and Studying Their Properties and Packaging

1983 • 274 citations

Plasmid ColE1 incompatibility determined by interaction of RNA I with primer transcript.

1981 • 262 citations

The macronuclear ribosomal DNA of Tetrahymena pyriformis is a palindrome

1976 • 224 citations

MOLECULAR GENETICS OF YEAST MATING TYPE

1982 • 219 citations

The Genetics of Antibody Diversity

1982 • 214 citations

Comparison of the sequences of macro- and micronuclear DNA of Tetrahymena pyriformis

1974 • 213 citations

Replication of each copy of the yeast 2 micron DNA plasmid occurs during the S phase

1979 • 211 citations

Base pairing of RNA I with its complementary sequence in the primer precursor inhibits ColE1 replication

1981 • 204 citations

Biology of Tetrahymena

1959 • 195 citations

The Problem of Germ Cell Determinants

1974 • 184 citations

Hybridization of nucleic acids directly in agarose gels

1983 • 183 citations

Phase variation: Genetic analysis of switching mutants

1980 • 183 citations

On plasmid incompatibility

1978 • 181 citations

Serial Transplantation of Embryonic Nuclei

1956 • 171 citations

DNA elimination in tetrahymena: A developmental process involving extensive breakage and rejoining of DNA at defined sites

1984 • 170 citations

DNA of ciliated protozoa: DNA sequence diminution during macronuclear development of oxytricha

1976 • 169 citations

A single integrated gene for ribosomal RNA in a eucaryote, tetrahymena pyriformis

1977 • 167 citations

Free ribosomal DNA molecules from Tetrahymena pyriformis GL are giant palindromes

1976 • 162 citations

Macro‐ and Micronuclei of Tetrahymena pyriformis: A Model System for Studying the Structure and Function of Eukaryotic Nuclei*†

1973 • 161 citations

Chromosome rearrangements in trypanosoma brucei

1984 • 161 citations

Free Ribosomal RNA Genes in the Macronucleus of Tetrahymena

1974 • 160 citations

Meiosis and Nuclear Behavior in Tetrahymena pyriformis*

1956 • 153 citations

Cytofluorimetric analysis of nuclear dna during meiosis, fertilization and macronuclear development in the ciliate Tetrahymena pyriformis, syngen 1

1975 • 145 citations

GENOME ORGANIZATION AND REORGANIZATION IN TETRAHYMENA

1980 • 142 citations

Cytologic and Autoradiographic Studies of the Micronucleus at Meiotic Prophase in Tetrahymena pyriformis

1974 • 133 citations

Developmental rearrangements associated with a single type of expressed α-tubulin gene in tetrahymena

1984 • 124 citations

Specific DNA rearrangements in synchronously developing nuclei of Tetrahymena.

1984 • 121 citations

A Small Number of Cistrons for Ribosomal RNA in the Germinal Nucleus of a Eukaryote, Tetrahymena pyriformis

1974 • 118 citations

Gene-sized DNA molecules of the macronuclei in three species of hypotrichs: Size distributions and absence of nicks

1980 • 111 citations

Research in Protozoology

1967 • 111 citations

CYTOCHEMICAL STUDIES ON THE PROBLEM OF MACRONUCLEAR SUBNUCLEI IN TETRAHYMENA

1972 • 109 citations

Repeated hexanucleotide C-C-C-C-A-A is present near free ends of macronuclear DNA of Tetrahymena.

1981 • 104 citations

The Size of Macronuclear DNA and Its Relationship to Models for Maintaining Genic Balance*†

1979 • 100 citations

A single base-pair alteration is responsible for the DNA overproduction phenotype of a plasmid copy-number mutant

1981 • 99 citations

Histone genes: Not so simple after all

1984 • 97 citations

Two separate regions of the extrachromosomal ribosomal deoxyribonucleic acid of Tetrahymena thermophila enable autonomous replication of plasmids in Saccharomyces cerevisiae.

1981 • 95 citations

Probable somatic DNA rearrangements in mating type determination in Tetrahymena thermophila: A review and a model

1981 • 94 citations

Cell Growth and Cell Division

1963 • 91 citations

Inverted terminal repeat sequence in the macronuclear DNA of Stylonychia pustulata

1980 • 90 citations

Molecular aspects of chromatin elimination in Ascaris lumbricoides

1972 • 88 citations

Chromosome Structure in Ciliated Protozoans

1974 • 87 citations

TetrahymenaH4 genes: structure, evolution and organization in macro- and micronuclei

1984 • 84 citations

Sequence-specific fragmentation of macronuclear DNA in a holotrichous ciliate

1981 • 84 citations

COMPARTMENTALIZATION OF THE DEVELOPING MACRONUCLEUS FOLLOWING CONJUGATION IN STYLONYCHIA AND EUPLOTES

1970 • 83 citations

Mating Type Determination in Tetrahymena Pyriformis

1953 • 83 citations

Control of DNA Replication in Bacteria

1978 • 80 citations

Tandemly repeated hexanucleotide at tetrahymena rDNA free end is generated from a single copy during development

1982 • 79 citations

Single extrachromosomal ribosomal rna gene copies are synthesized during amplification of the rDNA in tetrahymena

1981 • 76 citations

Ribosomal RNA gene amplification in tetrahymena may be associated with chromosome breakage and DNA elimination

1981 • 76 citations

Macronuclear DNA of the hypotrichous ciliate Oxytricha fallax

1978 • 75 citations

The Gene-size DNA Molecules in Oxytricha

1978 • 73 citations

Regulatory regions of ColE1 that are involved in determination of plasmid copy number.

1983 • 70 citations

Genome amplification and gene expression in the ciliate macronucleus

1972 • 70 citations

DNA Termini in Ciliate Macronuclei

1983 • 70 citations

Elimination of specific DNA sequences from the somatic nucleus of the ciliate Tetrahymena.

1982 • 69 citations

Allele-specific, selective amplification of a ribosomal RNA gene in tetrahymena thermophila

1982 • 69 citations

DNA of ciliated protozoa

1971 • 67 citations

The Amount of Ribosomal RNA Genes in Tetrahymena pyriformis in Different Physiological States

1972 • 66 citations

Gene Amplification in Tetrahymena thermophila: Formation of Extrachromosomal Palindromic Genes Coding for rRNA

1985 • 66 citations

Reproducible and variable genomic rearrangements occur in the developing somatic nucleus of the ciliate Tetrahymena thermophila.

1985 • 65 citations

Experiments on chromosome elimination in the gall midge, Mayetiola destructor

1970 • 65 citations

Sites Required for Position-Effect Regulation of Mating-type Information in Yeast

1983 • 64 citations

Immunoglobulin class switching: Developmentally regulated DNA rearrangements during differentiation

1980 • 62 citations

DNA Rearrangements Involving the Genes for Variant Antigens in Trypanosoma brucei

1981 • 58 citations

Nullisomic Tetrahymena: Eliminating Germinal Chromosomes

1981 • 57 citations

Polytene chromosomes of Oxytricha: Biochemical and morphological changes during macronuclear development in a ciliated protozoan

1976 • 57 citations

Alteration of the Tetrahymena Genome During Nuclear Differentiation*†

1979 • 52 citations

Elimination of DNA sequences during macronuclear differentiation in Tetrahymena thermophila, as detected by in situ hybridization

1982 • 50 citations

FURTHER EVIDENCE FOR LACK OF GENE EXPRESSION IN THE TETRAHYMENA MICRONUCLEUS

1981 • 49 citations

Vegetative Mutants and Clonal Senility in Tetrahymena*

1959 • 48 citations

L-chromosome inheritance and the problem of chromosome ?imprinting? in Sciara (Sciaridae, Diptera)

1971 • 48 citations

Germ line-specific DNA sequences are present on all five micronuclear chromosomes in Tetrahymena thermophila.

1983 • 46 citations

Genetic Evidence Concerning the Structure of the Tetrahymena thermophila Macronucleus*†

1979 • 46 citations

Tandemly repeated C-C-C-C-A-A hexanucleotide of Tetrahymena rDNA is present elsewhere in the genome and may be related to the alteration of the somatic genome.

1981 • 46 citations

Reorganization of unique and repetitive sequences during nuclear development in Tetrahymena thermophila

1982 • 44 citations

REGULATORY SEROTYPE MUTATIONS IN TETRAHYMENA PYRIFORMIS, SYNGEN 1

1973 • 43 citations

Gene amplification in Tetrahymena thermophila: formation of extrachromosomal palindromic genes coding for rRNA.

1985 • 43 citations

Chromatin diminution inAscaris suum: nucleotide sequence of the eliminated satellite DNA

1982 • 42 citations

Analysis of the Functional Components of the Phase Variation System

1981 • 42 citations

Evidence of Gene Diminution During the Formation of the Macronucleus in the Protozoan, Stylonychia

1972 • 41 citations

The 5S ribosomal RNA gene clusters in Tetrahymena thermophila: strain differences, chromosomal localization, and loss during micronuclear ageing

1984 • 36 citations

Biochemistry of Animal Development: The Biochemistry of Animal Development , Volume 1, Descriptive Biochemistry of Animal Development . Edited by Rudolf Weber. Academic Press, New York, 1965. 662 pp., $23.

1966 • 33 citations

Sequence organization within and flanking clusters of 5S ribosomal RNA genes inTetrahymena

1984 • 33 citations

Recombination Events That Activate, Diversify, and Delete Immunoglobulin Genes

1981 • 31 citations

Macronuclear Subunits of Tetrahymena thermophila Are Functionally Haploid

1977 • 28 citations

DNA amounts in the nuclei ofParamecium aurelia andTetrahymena pyriformis

1971 • 27 citations

LINKAGE STUDIES IN VARIETY 1 OF TETRAHYMENA PYRIFORMIS: A FIRST CASE OF LINKAGE IN THE CILIATED PROTOZOA

1964 • 24 citations

Kinetic complexity of Tetrahymena pyriformis nuclear deoxyribonucleic acid

1970 • 22 citations

Unequal gene amplification and transcription in the macronucleus of Tetrahymena pyriformis

1979 • 21 citations

Elimination of micronuclear specific DNA sequences early in anlagen development.

1985 • 21 citations

Strong sequence conservation of a 38 bp region near the center of the extrachromosomal rDNA palindrome in differentTetrahymenaspecies

1983 • 19 citations

Mating type differentiation in Tetrahymena thermophila: Strong influence of delayed refeeding of conjugating pairs

1983 • 19 citations

Viscoelastic studies on Tetrahymena macronuclear DNA.

1978 • 19 citations

The regulation of amounts and proportions of genetic elements in the macronuclei of Tetrahymena thermophila strains of diverse karyotype

1979 • 17 citations

Synthesis of ribosomal DNA in conjugating Tetrahymena

1979 • 15 citations

Evidence for Chromosomal Macronuclear Substructures in Tetrahymena*†

1979 • 12 citations

Rearrangement of the 5S ribosomal RNA gene clusters during the development and replication of the macronucleus in Tetrahymena thermophila

1984 • 10 citations

Genome structure of Tetrahymena pyriformiis

1978 • 9 citations