Genetic Polymorphism among Enzyme Loci

A MOLECULAR APPROACH TO THE STUDY OF GENIC HETEROZYGOSITY IN NATURAL POPULATIONS. II. AMOUNT OF VARIATION AND DEGREE OF HETEROZYGOSITY IN NATURAL POPULATIONS OF DROSOPHILA PSEUDOOBSCURA

1966 • 1,189 citations

Starch-gel electrophoresis—Application to the classification of pituitary proteins and polypeptides

1964 • 964 citations

Gene Mutations in Human Hæmoglobin: the Chemical Difference Between Normal and Sickle Cell Hæmoglobin

1957 • 938 citations

C. Genetics of Man Enzyme polymorphisms in man

1966 • 612 citations

Enzyme Polymorphism and Metabolism

1974 • 284 citations

A profile of Drosophila species' enzymes assayed by electrophoresis. I. Number of alleles, heterozygosities, and linkage disequilibrium in glucose-metabolizing systems and some other enzymes

1970 • 245 citations

ADAPTATION AT SPECIFIC LOCI. I. NATURAL SELECTION ON PHOSPHOGLUCOSE ISOMERASE OF COLIAS BUTTERFLIES: BIOCHEMICAL AND POPULATION ASPECTS

1977 • 233 citations

GENETIC HETEROGENEITY WITHIN ELECTROPHORETIC "ALLELES" OF XANTHINE DEHYDROGENASE IN DROSOPHILA PSEUDOOBSCURA

1976 • 219 citations

The degree of polymorphisms in enzymes involved in energy production compared to that in nonspecific enzymes in two Drosophila ananassae populations.

1968 • 203 citations

Regulation of Intermediary Metabolism, with Special Reference to the Control Mechanisms in Insect Flight Muscle

1970 • 189 citations

Genetic Polymorphisms in Varied Environments

1971 • 188 citations

Still More Genetic Variability in Natural Populations

1973 • 164 citations

Regulatory Aspects of Photosynthetic Carbon Metabolism

1976 • 154 citations

Adaptive response due to changes in gene regulation: a study with Drosophila.

1977 • 135 citations

LACK OF GENIC SIMILARITY BETWEEN TWO SIBLING SPECIES OF DROSOPHILA AS REVEALED BY VARIED TECHNIQUES

1976 • 129 citations

Organization of the rosy locus in Drosophila melanogaster

1977 • 121 citations

Geographic Distribution and Enzymatic Properties of Lactate Dehydrogenase Allozymes in the Fathead Minnow, Pimephales promelas

1972 • 97 citations

Polymorphism and the subunit structure of enzymes: a contribution to the neutralist-selectionist controversy.

1977 • 96 citations

Adaptation of Photosynthetic Processes to Stress

1975 • 94 citations

Population biology of plants

1979 • 91 citations

The relative quantities and catalytic activities of enzymes produced by alleles at the alcohol dehydrogenase locus in Drosophila melanogaster

1974 • 88 citations

THE STUDY OF GENIC VARIATION BY ELECTROPHORETIC AND HEAT DENATURATION TECHNIQUES AT THE OCTANOL DEHYDROGENASE LOCUS IN MEMBERS OF THE DROSOPHILA VIRILIS GROUP

1975 • 86 citations

Molecular Heterosis for Heat-Sensitive Enzyme Alleles

1974 • 77 citations

HIDDEN ALLELES AT THE α-GLYCEROPHOSPHATE DEHYDROGENASE LOCUS IN COLIAS BUTTERFLIES

1976 • 68 citations

Variation between electrophoretically identical alleles at the alcohol dehydrogenase locus in Drosophila melanogaster

1975 • 66 citations

Isolation and genetic characterization of alcohol dehydrogenase thermostability variants occurring in natural populations of Drosophila melanogaster

1977 • 60 citations

Assessing Electrophoretic Similarity: The Problem of Hidden Heterogeneity

1977 • 60 citations

POST-TRANSLATIONAL MODIFICATION AS A POTENTIAL EXPLANATION OF HIGH LEVELS OF ENZYME POLYMORPHISM: XANTHINE DEHYDROGENASE AND ALDEHYDE OXIDASE IN DROSOPHILA MELANOGASTER

1979 • 58 citations

Further evidence of thermostability variation within electrophoretic mobility classes of enzymes

1976 • 53 citations

Thermostability studies for investigating non-electrophoretic polymorphic alleles in Drosophila melanogaster

1976 • 49 citations

Subunit size and genetic variation of enzymes in natural populations of Drosophila

1977 • 49 citations

Enzyme Polymorphism and Biosystematics: The Hypothesis of Selective Neutrality

1973 • 39 citations

Xanthine dehydrogenase from Drosophila melanogaster

1977 • 39 citations

Polymorphism and protein evolution. The neutral mutation-random drift hypothesis.

1971 • 38 citations

Characterization of electrophoretically cryptic variation in the alpine butterfly Colias meadii

1977 • 36 citations

Polymorphism and predictability at the ?-glycerophosphate dehydrogenase locus in Colias butterflies: Gradients in allele frequency within single populations

1976 • 34 citations

Importance of Substrate Variability to Enzyme Polymorphism

1973 • 32 citations

Metabolic Implications of Polymorphism as an Adaptive Strategy

1971 • 31 citations

Analysis of Enzyme Variation in Natural Populations of the Butterfly Colias eurytheme

1971 • 23 citations

Gene expression in Drosophila: Post-translational modification of aldehyde oxidase and xanthine dehydrogenase

1979 • 23 citations

THE EFFECT OF COMBINING ALLELES INTO ELECTROPHORETIC CLASSES ON DETECTING LINKAGE DISEQUILIBRIUM

1977 • 23 citations

EVALUATION OF THE STEPWISE MUTATION MODEL OF ELECTROPHORETIC MOBILITY: COMPARISON OF THE GEL SIEVING BEHAVIOR OF ALLELES AT THE ESTERASE-5 LOCUS OF DROSOPHILA PSEUDOOBSCURA

1977 • 21 citations

Measuring Selection in Natural Populations.

1978 • 20 citations

A high order of heterogeneity in the serum albumin of ensatina eschscholtzi, a pacific coast salamander

1970 • 10 citations

Enzyme Polymorphism and Adaptation in Alpine Butterflies

1976 • 10 citations

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