The Induction of Resistance to Alkylation Damage in Mammalian Cells

IARC Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans

1980 • 3,166 citations

Possible Relevance of O–6 Alkylation of Deoxyguanosine to the Mutagenicity and Carcinogenicity of Nitrosamines and Nitrosamides

1969 • 949 citations

A new pathway for DNA repair in Escherichia coli

1977 • 705 citations

Differential giemsa staining of sister chromatids and the study of sister chromatid exchanges without autoradiography

1974 • 598 citations

Sister chromatid exchange as an indicator of mutagenesis

1978 • 504 citations

Methylation of deoxyribonucleic acid in cultured mammalian cells by N-methyl-N′-nitro-N-nitrosoguanidine. The influence of cellular thiol concentrations on the extent of methylation and the 6-oxygen atom of guanine as a site of methylation

1970 • 500 citations

Persistence of O 6-Ethylguanine in Rat-Brain DNA: Correlation with Nervous System-Specific Carcinogenesis by Ethylnitrosourea

1974 • 495 citations

Repair of alkylated DNA in Escherichia coli. Methyl group transfer from O6-methylguanine to a protein cysteine residue.

1980 • 438 citations

The properties of in templates for RNA polymerase

1973 • 264 citations

Adaptive response to alkylating agents involves alteration in situ of O6-methylguanine residues in DNA

1979 • 260 citations

Sister chromatid exchanges induced by mutagenic carcinogens in normal and xeroderma pigmentosum cells

1977 • 238 citations

An adaptive response of E. coli to low levels of alkylating agent: Comparison with previously characterised DNA repair pathways

1977 • 225 citations

Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines

1980 • 218 citations

Repair of O6-methylguanine in adapted Escherichia coli.

1978 • 180 citations

Isolation and characterization of Escherichia coli K-12 mutants unable to induce the adaptive response to simple alkylating agents

1979 • 160 citations

Quantitation of the adaptive response to alkylating agents

1979 • 145 citations

Increased excision of O6-methylguanine from rat liver DNA after chronic administration of dimethylnitrosamine.

1979 • 101 citations

Effect of chronic treatment of rats with dimethylnitrosamine on the removal of O6-methylguanine from DNA.

1980 • 99 citations

Inability of Chinese hamster ovary cells to excise O6-alkylguanine.

1980 • 98 citations

Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents

1978 • 95 citations

Differential repair of O6-methylguanine in DNA of rat hepatocytes and nonparenchymal cells

1980 • 80 citations

The stability of methylated purines and of methylphosphotriesters in the DNA of V79 cells after treatment with N-methyl-N-nitrosourea

1979 • 80 citations

HeLa cell variants that differ in sensitivity to monofunctional alkylating agents, with independence of cytotoxic and mutagenic responses

1979 • 65 citations

Efficiency of the adaptive response of Escherichia coli to alkylating agents

1980 • 61 citations

The adaptive response of E. coli to low levels of alkylating agent: The role of polA in killing adaptation

1978 • 56 citations

In Vitro Studies of Chemical Mutagens and Carcinogens. I. Stability Studies in Cell Culture Medium2

1977 • 47 citations

Reduced DNA repair in mouse satellite DNA after treatment with methyl-methanesulfonate, and N-methyl-N-nitrosourea

1976 • 35 citations

Calcium-induced decrease in membrane fluidity of sea urchin egg cortex after fertilization

1980 • 32 citations

Kinetics of mutation and sister-chromatid exchange induction by ethyl methanesulfonate in Chinese hamster ovary cells

1981 • 7 citations