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Association Between Gait Assessed by Intelligent System and Cognitive Function in Silent Cerebrovascular Disease

NCT04456348

NULLOBSERVATIONAL
Shanghai Zhongshan Hospital
1,600 participants
Started 2020-07-01 · Completed 2021-12-31
Status: Unknown (as of 12-23-2025)

Conditions

Silent Stroke

Linked Papers (from SciSciNet-V2)

Total Papers16
Background
10
Result
0
Derived
0
Unknown
6

Total Citations Per Year

Brief Summary

This study is a multi-center prospective cohort study. We will continuously recruit subjects with silent cerebrovascular disease aged 60 to 85 years from Shanghai and Guizhou. Data including demographic characteristics, medical history, other concomitant diseases, neurological function assessments, laboratory examinations, imaging examinations, and other clinical data and health economics survey responses will be collected from all subjects. At baseline, all subjects will undergo gait assessment using the intelligent system and cognitive function scale assessment by clinicians. According to the intelligent gait results, the subjects will be divided into normal and abnormal gait groups. All subjects will be observed naturally for 1 year, and all medical behaviors will be recorded. All subjects will be interviewed by telephone for the occurrence of vascular events and changes in medical behaviors at half a year after enrollment and followed up at 1 year after enrollment, including gait evaluation using the intelligent system and cognitive function scale evaluation by clinicians. During the follow-up period, patients can visit the hospital for follow-up at any time when their condition changes.

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Background Papers20

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
2013
4,554 citations
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
2013
4,554 citations
Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010
2013
3,583 citations
Global and regional burden of stroke during 1990–2010: findings from the Global Burden of Disease Study 2010
2013
3,583 citations
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis
2010
2,042 citations
The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis
2010
2,042 citations
Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment
2017
290 citations
Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment
2017
290 citations
Regional White Matter Hyperintensity Volume, Not Hippocampal Atrophy, Predicts Incident Alzheimer Disease in the Community
2012
230 citations
Regional White Matter Hyperintensity Volume, Not Hippocampal Atrophy, Predicts Incident Alzheimer Disease in the Community
2012
230 citations
Functional Impact of White Matter Hyperintensities in Cognitively Normal Elderly Subjects
2010
163 citations
Functional Impact of White Matter Hyperintensities in Cognitively Normal Elderly Subjects
2010
163 citations
White matter hyperintensities are related to physical disability and poor motor function
2005
157 citations
White matter hyperintensities are related to physical disability and poor motor function
2005
157 citations
Coevolution of white matter hyperintensities and cognition in the elderly
2012
153 citations
Coevolution of white matter hyperintensities and cognition in the elderly
2012
153 citations
White Matter Hyperintensities Predict Functional Decline in Voiding, Mobility, and Cognition in Older Adults
2010
110 citations
White Matter Hyperintensities Predict Functional Decline in Voiding, Mobility, and Cognition in Older Adults
2010
110 citations
Prognostic Impact of Cerebral Small Vessel Disease on Stroke Outcome
2015
82 citations
Prognostic Impact of Cerebral Small Vessel Disease on Stroke Outcome
2015
82 citations

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked