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New IDEAS: Imaging Dementia-Evidence for Amyloid Scanning Study
NCT04426539
NULLOBSERVATIONAL
American College of Radiology
7,000 participants
Started 2020-12-17 · Completed 2024-12-31
Status: Recruiting (as of 12-23-2025)
Conditions
Alzheimer's DiseaseDementiaMild Cognitive Impairment
Interventions
Linked Papers (from SciSciNet-V2)
Total Papers69
Background
34Result
0Derived
0Unknown
35Total Citations Per Year
Brief Summary
New IDEAS is an observational, open-label, longitudinal cohort study designed to address the requirements of the CED provisions of the NCD on beta-amyloid PET. Building on the initial Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) study, New IDEAS will evaluate the association between amyloid PET and patient-centered outcomes in an expanded and more ethnoracially and clinically diverse group of Medicare participants presenting with cognitive impairment.
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Background Papers68
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
2011
16,302 citations
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
2011
16,302 citations
NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease
2018
7,248 citations
NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease
2018
7,248 citations
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
2012
2,551 citations
National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease
2012
2,551 citations
Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010
2012
927 citations
Accuracy of the Clinical Diagnosis of Alzheimer Disease at National Institute on Aging Alzheimer Disease Centers, 2005–2010
2012
927 citations
Inequalities in dementia incidence between six racial and ethnic groups over 14 years
2016
673 citations
Inequalities in dementia incidence between six racial and ethnic groups over 14 years
2016
673 citations
Prevalence of Amyloid PET Positivity in Dementia Syndromes
2015
562 citations
Prevalence of Amyloid PET Positivity in Dementia Syndromes
2015
562 citations
Association of Incident Dementia With Hospitalizations
2012
479 citations
Association of Incident Dementia With Hospitalizations
2012
479 citations
Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia
2019
470 citations
Association of Amyloid Positron Emission Tomography With Subsequent Change in Clinical Management Among Medicare Beneficiaries With Mild Cognitive Impairment or Dementia
2019
470 citations
The behavioural/dysexecutive variant of Alzheimer’s disease: clinical, neuroimaging and pathological features
2015
444 citations
The behavioural/dysexecutive variant of Alzheimer’s disease: clinical, neuroimaging and pathological features
2015
444 citations
A Systematic Review of Community‐Based Participatory Research to Enhance Clinical Trials in Racial and Ethnic Minority Groups
2012
355 citations
A Systematic Review of Community‐Based Participatory Research to Enhance Clinical Trials in Racial and Ethnic Minority Groups
2012
355 citations
Age-specific and Sex-specific Prevalence and Incidence of Mild Cognitive Impairment, Dementia, and Alzheimer Dementia in Blacks and Whites
2011
328 citations
Age-specific and Sex-specific Prevalence and Incidence of Mild Cognitive Impairment, Dementia, and Alzheimer Dementia in Blacks and Whites
2011
328 citations
Racial Differences in the Impact of Elevated Systolic Blood Pressure on Stroke Risk
2012
225 citations
Racial Differences in the Impact of Elevated Systolic Blood Pressure on Stroke Risk
2012
225 citations
Multisite study of the relationships between antemortem [11C]PIB‐PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology
2018
202 citations
Multisite study of the relationships between antemortem [11C]PIB‐PET Centiloid values and postmortem measures of Alzheimer's disease neuropathology
2018
202 citations
Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use
2019
164 citations
Effect of Collaborative Dementia Care via Telephone and Internet on Quality of Life, Caregiver Well-being, and Health Care Use
2019
164 citations
Amyloid-β 11 C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials
2015
140 citations
Amyloid-β 11 C-PiB-PET imaging results from 2 randomized bapineuzumab phase 3 AD trials
2015
140 citations
The National Cancer Institute–American Society of Clinical Oncology Cancer Trial Accrual Symposium: Summary and Recommendations
2013
133 citations
The National Cancer Institute–American Society of Clinical Oncology Cancer Trial Accrual Symposium: Summary and Recommendations
2013
133 citations
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
2017
132 citations
Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia
2017
132 citations
Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort
2018
113 citations
Association of Amyloid Positron Emission Tomography With Changes in Diagnosis and Patient Treatment in an Unselected Memory Clinic Cohort
2018
113 citations
Amyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI
2016
109 citations
Amyloid negativity in patients with clinically diagnosed Alzheimer disease and MCI
2016
109 citations
Implications of Increased C-Reactive Protein for Cardiovascular Risk Stratification in Black and White Men and Women in the US
2009
84 citations
Implications of Increased C-Reactive Protein for Cardiovascular Risk Stratification in Black and White Men and Women in the US
2009
84 citations
Effective Recruitment Strategies and Community-Based Participatory Research: Community Networks Program Centers' Recruitment in Cancer Prevention Studies
2014
81 citations
Effective Recruitment Strategies and Community-Based Participatory Research: Community Networks Program Centers' Recruitment in Cancer Prevention Studies
2014
81 citations
Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques
2015
77 citations
Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques
2015
77 citations
Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer’s Disease Center
2019
76 citations
Neuropathological Diagnoses of Demented Hispanic, Black, and Non-Hispanic White Decedents Seen at an Alzheimer’s Disease Center
2019
76 citations
Dementia Increases the Risks of Acute Organ Dysfunction, Severe Sepsis and Mortality in Hospitalized Older Patients: A National Population-Based Study
2012
71 citations
Dementia Increases the Risks of Acute Organ Dysfunction, Severe Sepsis and Mortality in Hospitalized Older Patients: A National Population-Based Study
2012
71 citations
Risk Factors for Intracerebral Hemorrhage
2013
69 citations
Risk Factors for Intracerebral Hemorrhage
2013
69 citations
Excess costs of dementia disorders and the role of age and gender - an analysis of German health and long-term care insurance claims data
2012
68 citations
Excess costs of dementia disorders and the role of age and gender - an analysis of German health and long-term care insurance claims data
2012
68 citations
African ancestry protects against Alzheimer's disease-related neuropathology
2011
65 citations
African ancestry protects against Alzheimer's disease-related neuropathology
2011
65 citations
Advancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit
2012
58 citations
Advancing Alzheimer's disease diagnosis, treatment, and care: Recommendations from the Ware Invitational Summit
2012
58 citations
Validation of a polygenic risk score for dementia in black and white individuals
2014
57 citations
Validation of a polygenic risk score for dementia in black and white individuals
2014
57 citations
Mild Physical Impairment Predicts Future Diagnosis of Dementia of the Alzheimer's Type
2013
55 citations
Mild Physical Impairment Predicts Future Diagnosis of Dementia of the Alzheimer's Type
2013
55 citations
Case Study: Community Engagement and Clinical Trial Success: Outreach to African American Women
2015
44 citations
Introduction to the Science of Recruitment and Retention Among Ethnically Diverse Populations
2011
44 citations
Introduction to the Science of Recruitment and Retention Among Ethnically Diverse Populations
2011
44 citations
Case Study: Community Engagement and Clinical Trial Success: Outreach to African American Women
2015
44 citations
African Caribbeans have greater subclinical cerebrovascular disease than Europeans
2013
17 citations
African Caribbeans have greater subclinical cerebrovascular disease than Europeans
2013
17 citations
Associations between Markers of Glucose and Insulin Function and Cognitive Function in Healthy African American Elders
2015
8 citations
Associations between Markers of Glucose and Insulin Function and Cognitive Function in Healthy African American Elders
2015
8 citations
Result Papers0
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Unknown Papers35
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)
1991
4,669 citations
Distrust, Race, and Research
2002
988 citations
The <EMPH TYPE="ITAL">APOE</EMPH>-∊4 Allele and the Risk of Alzheimer Disease Among African Americans, Whites, and Hispanics
1998
741 citations
Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
2012
732 citations
Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan
2001
678 citations
Appropriate use criteria for amyloid PET: A report of the Amyloid Imaging Task Force, the Society of Nuclear Medicine and Molecular Imaging, and the Alzheimer's Association
2013
534 citations
Epidemiology of Dementias and Alzheimer’s Disease
2012
484 citations
Vitamin D Deficiency Is Associated With Low Mood and Worse Cognitive Performance in Older Adults
2006
465 citations
Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study
2015
455 citations
Prevalence of Dementia in Older Latinos: The Influence of Type 2 Diabetes Mellitus, Stroke and Genetic Factors
2003
398 citations
Rates of dementia in three ethnoracial groups
1999
394 citations
The Relationship Between a Dementia Diagnosis, Chronic Illness, Medicare Expenditures, and Hospital Use
2004
388 citations
Accelerated Weight Loss May Precede Diagnosis in Alzheimer Disease
2006
315 citations
Phase 3 Trial of Flutemetamol Labeled With Radioactive Fluorine 18 Imaging and Neuritic Plaque Density
2015
266 citations
Dementia in Elderly Persons in a General Hospital
2000
181 citations
Apolipoprotein E epsilon4 and incidence of Alzheimer disease in a community population of older persons.
1997
174 citations
The Accurate Diagnosis of Early-Onset Dementia
2006
173 citations
The Prevalence and 3-Year Incidence of Dementia in Older Black and White Community Residents
1998
167 citations
Incidence and prevalence of dementia in a multiethnic cohort of municipal retirees
1997
144 citations
Causes of Hospital Admission for People With Dementia: A Systematic Review and Meta-Analysis
2013
128 citations
Decreased Hippocampal 5-HT2A Receptor Binding in Older Depressed Patients Using [18F]Altanserin Positron Emission Tomography
2004
78 citations
Racial Differences in Cognitive Decline in a Sample of Community-Dwelling Older Adults
2005
77 citations
Dementia Undiagnosed in Poor Older Adults with Functional Impairment
2007
72 citations
The prevalence of the neuropathological lesions of Alzheimer’s disease is independent of race and gender
2001
67 citations
Investigator beliefs and reported success in recruiting minority participants
2006
50 citations
APOE and APOC1 Promoter Polymorphisms and the Risk of Alzheimer Disease in African American and Caribbean Hispanic Individuals
2004
48 citations
Racial differences in the etiology of dementia and frequency of Alzheimer lesions in the brain.
1989
44 citations
Recruitment methods for survey research: Findings from the Mid-South Clinical Data Research Network
2017
43 citations
The Neuropathology of Alzheimer Disease in African American and White Individuals
2006
41 citations
The Prevalence of Alzheimer Neuropathologic Lesions Is Similar in Blacks and Whites
2006
33 citations
Recruitment Strategies for Studying Dementia in Later Life among Diverse Cultural Groups
2005
25 citations
Beyond Diversity to Inclusion
2010
20 citations
Predictors of Discrepancy Between Care Recipients With Mild-to-Moderate Dementia and Their Caregivers on Perceptions of the Care Recipients’ Quality of Life
2016
14 citations
A Community-Based Collaborative Care Model to Improve Functional Health in Underserved Community-Dwelling Older Adults
2017
3 citations
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