Hemostatic Agent Use and Intraoperative Blood Loss in Lumbar Spine Surgery

NCT04058665

NULLOBSERVATIONAL

Johns Hopkins University

300 participants

Started 2019-06-18 · Completed 2022-03-01

Status: Completed (as of 12-23-2025)

Conditions

Blood Loss

Interventions

DEVICE: Floseal

Linked Papers (from SciSciNet-V2)

Total Papers36

Background

9

Result

0

Derived

0

Unknown

27

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

Perioperative variables that can be used to create a bundled approach quality improvement protocol to minimize blood loss in spine surgery will be evaluated using retrospective data collection and multivariate analysis of previously performed spinal surgeries at Johns Hopkins Hospital. In particular the investigators are interested in determining whether FloSeal® contributes towards increased control over perioperative bleeding compared to other hemostatic agents for potential inclusion in a future bundled approach.

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Background Papers18

Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery

1,228 citations

Liberal or Restrictive Transfusion in High-Risk Patients after Hip Surgery

1,228 citations

Blood loss in adult spinal surgery

Blood loss in adult spinal surgery

Reducing Noninfectious Risks of Blood Transfusion

Reducing Noninfectious Risks of Blood Transfusion

Controlled hypotension for spinal surgery

Controlled hypotension for spinal surgery

Impact of Red Blood Cell Transfusion on Global and Regional Measures of Oxygenation

Impact of Red Blood Cell Transfusion on Global and Regional Measures of Oxygenation

A Simple “Blood-Saving Bundle” Reduces Diagnostic Blood Loss and the Transfusion Rate in Mechanically Ventilated Patients

A Simple “Blood-Saving Bundle” Reduces Diagnostic Blood Loss and the Transfusion Rate in Mechanically Ventilated Patients

Radiofrequency bipolar hemostatic sealer reduces blood loss, transfusion requirements, and cost for patients undergoing multilevel spinal fusion surgery: a case control study

Radiofrequency bipolar hemostatic sealer reduces blood loss, transfusion requirements, and cost for patients undergoing multilevel spinal fusion surgery: a case control study

Risk analysis of blood transfusion requirements in emergency and elective spinal surgery

Risk analysis of blood transfusion requirements in emergency and elective spinal surgery

Perioperative blood management

Perioperative blood management

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers27

A Multicenter, Randomized, Controlled Clinical Trial of Transfusion Requirements in Critical Care

4,950 citations

Transfusion Requirements After Cardiac Surgery

Effect of blood transfusion on long-term survival after cardiac operation

Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention

Association between Intraoperative Blood Transfusion and Mortality and Morbidity in Patients Undergoing Noncardiac Surgery

Transfusion in Coronary Artery Bypass Grafting is Associated with Reduced Long-Term Survival

Effect of peri-operative red blood cell transfusion on 30-day and 1-year mortality following coronary artery bypass surgery

Predictors of Blood Transfusions in Spinal Instrumentation and Fusion Surgery

Instrumented and Noninstrumented Posterolateral Fusion in Adult Spondylolisthesis

Patient Blood Management Bundles to Facilitate Implementation

Transfusion Requirements in Surgical Oncology Patients

Tranexamic acid reduces blood transfusion in total knee arthroplasty even when a blood conservation program is applied

Deliberate hypotension in orthopedic surgery reduces blood loss and transfusion requirements: A meta-analysis of randomized controlled trials

Rotational thromboelastometry–guided blood product management in major spine surgery

Allogeneic blood transfusions and postoperative infections after lumbar spine surgery

Predictors of transfusion for spinal surgery in Maryland, 1997 to 2000

Clinical and molecular basis of transfusion-induced immunomodulation: summary of the proceedings of a state-of-the-art conference*

A Multifaceted Intervention to Improve Compliance With Process Measures for ICU Clinician Communication With ICU Patients and Families*

An assessment of the necessity of transfusion during pancreatoduodenectomy

Acute Kidney Injury Care Bundles

Negative Effects of Transfused Blood Components after Hepatectomy for Metastatic Colorectal Cancer

British Thoracic Society community-acquired pneumonia care bundle: results of a national implementation project: Table 1

Indications for intraoperative blood salvage.

Hemostatic Agents in Spine Surgery