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Cognitive Remediation and Supported Education in Psychotic Disorders

NCT04040829

NAINTERVENTIONAL
Centre de Recherche de l'Institut Universitaire en Santé Mentale de Québec
80 participants
Started 2021-09-01 · Completed 2024-09
Status: Suspended (as of 12-23-2025)

Conditions

Psychotic Disorders

Linked Papers (from SciSciNet-V2)

Total Papers39
Background
16
Result
0
Derived
0
Unknown
23

Total Citations Per Year

Brief Summary

This trial aims to assess the added value of cognitive remediation therapy to supported education intervention in young adults with a psychotic disorder. The objectives of this study are threefold: The first objective is to evaluate the efficacy of supported education and cognitive remediation therapy for young adults with psychotic disorders in terms of academic outcome (primary outcome) and cognitive, neurobiological, and psychological outcomes (secondary outcomes). The second objective is to explore mechanisms of change in academic outcomes using a multidimensional approach (cognitive, psychological and biological characteristics) in youth with psychotic disorders. The third objective is to investigate the patients' perspectives regarding their appreciation of the supported education programs. Academic outcomes, cognitive performance as well as psychological and genetic variables will collected at baseline (T0). Participants will then be randomized either to the experimental condition (Cognitive remediation + Supported education + Treatment as usual) or the control condition (Supported education + Treatment as usual) for three months. Directly after the end of treatment (T1) and three months following the end of treatment (T2), the same measures as baseline will be repeated. One year post-treatment (T3), a last assessment will be conducted for academic outcomes.To assess qualitative experience of patients enrolled in supported education, a subsample of the randomized controlled trial will be recruited to participate in a photovoice activity.

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Background Papers32

Generalizability of the Individual Placement and Support (IPS) model of supported employment outside the US
2012
334 citations
Generalizability of the Individual Placement and Support (IPS) model of supported employment outside the US
2012
334 citations
Neurocognitive Predictors of Work Outcome in Recent-Onset Schizophrenia
2011
289 citations
Neurocognitive Predictors of Work Outcome in Recent-Onset Schizophrenia
2011
289 citations
Photovoice as a Method for Revealing Community Perceptions of the Built and Social Environment
2011
278 citations
Photovoice as a Method for Revealing Community Perceptions of the Built and Social Environment
2011
278 citations
Work, Recovery, and Comorbidity in Schizophrenia: A Randomized Controlled Trial of Cognitive Remediation
2009
257 citations
Work, Recovery, and Comorbidity in Schizophrenia: A Randomized Controlled Trial of Cognitive Remediation
2009
257 citations
Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta-analysis
2017
168 citations
Interventions for obtaining and maintaining employment in adults with severe mental illness, a network meta-analysis
2017
168 citations
Genetic Variation in Catechol-O-Methyltransferase: Effects on Working Memory in Schizophrenic Patients, Their Siblings, and Healthy Controls
2007
130 citations
Genetic Variation in Catechol-O-Methyltransferase: Effects on Working Memory in Schizophrenic Patients, Their Siblings, and Healthy Controls
2007
130 citations
A new generation computerised metacognitive cognitive remediation programme for schizophrenia (CIRCuiTS): a randomised controlled trial
2017
121 citations
A new generation computerised metacognitive cognitive remediation programme for schizophrenia (CIRCuiTS): a randomised controlled trial
2017
121 citations
Combination Training in Aging Individuals Modifies Functional Connectivity and Cognition, and Is Potentially Affected by Dopamine-Related Genes
2012
76 citations
Combination Training in Aging Individuals Modifies Functional Connectivity and Cognition, and Is Potentially Affected by Dopamine-Related Genes
2012
76 citations
Prevalence and correlates of school drop-out prior to initial treatment of nonaffective psychosis: Further evidence suggesting a need for supported education
2009
68 citations
Prevalence and correlates of school drop-out prior to initial treatment of nonaffective psychosis: Further evidence suggesting a need for supported education
2009
68 citations
Neuroscience-informed auditory training in schizophrenia: A final report of the effects on cognition and serum brain-derived neurotrophic factor
2015
56 citations
Neuroscience-informed auditory training in schizophrenia: A final report of the effects on cognition and serum brain-derived neurotrophic factor
2015
56 citations
Enhancing return to work or school after a first episode of schizophrenia: the UCLA RCT of Individual Placement and Support and Workplace Fundamentals Module training
2019
48 citations
Enhancing return to work or school after a first episode of schizophrenia: the UCLA RCT of Individual Placement and Support and Workplace Fundamentals Module training
2019
48 citations
Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders
2016
43 citations
Personalised treatment for cognitive dysfunction in individuals with schizophrenia spectrum disorders
2016
43 citations
Genetic correlate of cognitive training response in schizophrenia
2012
39 citations
Does Change in Cognitive Function Predict Change in Costs of Care for People With a Schizophrenia Diagnosis Following Cognitive Remediation Therapy?
2014
39 citations
Genetic correlate of cognitive training response in schizophrenia
2012
39 citations
Does Change in Cognitive Function Predict Change in Costs of Care for People With a Schizophrenia Diagnosis Following Cognitive Remediation Therapy?
2014
39 citations
A feasibility study of a new computerised cognitive remediation for young adults with schizophrenia
2015
19 citations
A feasibility study of a new computerised cognitive remediation for young adults with schizophrenia
2015
19 citations
Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
2017
16 citations
Improving Theory of Mind in Schizophrenia by Targeting Cognition and Metacognition with Computerized Cognitive Remediation: A Multiple Case Study
2017
16 citations

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers23

Photovoice: Concept, Methodology, and Use for Participatory Needs Assessment
1997
4,495 citations
The relationship between neurocognition and social cognition with functional outcomes in schizophrenia: A meta-analysis
2010
1,684 citations
A Meta-Analysis of Cognitive Remediation for Schizophrenia: Methodology and Effect Sizes
2011
1,557 citations
Facial Emotion Recognition in Schizophrenia: Intensity Effects and Error Pattern
2003
748 citations
Neurocognitive Enhancement Therapy With Work Therapy
2001
356 citations
Cognitive Training for Supported Employment: 2-3 Year Outcomes of a Randomized Controlled Trial
2007
291 citations
Review on vocational predictors: a systematic review of predictors of vocational outcomes among individuals with schizophrenia: an update since 1998.
2010
227 citations
Cognitive Functioning in Schizophrenia
2004
223 citations
Exploring cognitive complaints in schizophrenia: the subjective scale to investigate cognition in schizophrenia
2003
192 citations
Investigating self-esteem in individuals with schizophrenia: Relevance of the Self-Esteem Rating Scale-Short Form
2006
186 citations
Role of BDNF epigenetics in activity-dependent neuronal plasticity
2013
168 citations
DNA methylation of the BDNF gene and its relevance to psychiatric disorders
2013
159 citations
Cognitive Strategies Versus Self-Management Skills as Adjunct to Vocational Rehabilitation
2005
134 citations
Mortality from Leading Causes by Education and Race in the United States, 2001
2008
125 citations
Influence of catechol-O-methyltransferase Val158Met polymorphism on neuropsychological and functional outcomes of classical rehabilitation and cognitive remediation in schizophrenia
2007
99 citations
Mentalizing in first-episode psychosis
2012
86 citations
Factors affecting cognitive remediation response in schizophrenia: The role of COMT gene and antipsychotic treatment
2014
60 citations
Employment outcomes for people with schizophrenia spectrum disorder: A meta-analysis of randomized controlled trials
2017
57 citations
Development and preliminary validation of the First Episode Social Functioning Scale for early psychosis
2014
40 citations
Brief Reports: The Fidelity of Supported Employment Implementation in Canada and the United States
2005
36 citations
Individual placement and support, supported education in young people with mental illness: an exploratory feasibility study
2016
36 citations
Cognitive remediation for individuals with psychosis in a supported education setting: A randomized controlled trial
2014
30 citations
Being visible: PhotoVoice as assessment for children in a school-based psychiatric setting
2016
22 citations