Cabozantinib in Patients With Advanced Penile Squamous Cell Carcinoma (PSCC) (CaboPen)

NCT03943602

PHASE2INTERVENTIONAL

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

37 participants

Started 2019-08-01 · Completed 2022-09-01

Status: Unknown (as of 12-23-2025)

Conditions

Penile Squamous Cell Carcinoma

Interventions

DRUG: Cabozantinib

Linked Papers (from SciSciNet-V2)

Total Papers64

Background

Result

Derived

Unknown

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

Cabozantinib in patients with advanced penile squamous cell carcinoma (PSCC): an open-label, single-center, phase 2, single-arm trial (CaboPen)

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Background Papers8

Detection and Typing of Human Papillomavirus DNA in Penile Carcinoma

2001

434 citations

Detection and Typing of Human Papillomavirus DNA in Penile Carcinoma

2001

434 citations

Neoadjuvant Paclitaxel, Ifosfamide, and Cisplatin Chemotherapy for Metastatic Penile Cancer: A Phase II Study

2010

338 citations

Neoadjuvant Paclitaxel, Ifosfamide, and Cisplatin Chemotherapy for Metastatic Penile Cancer: A Phase II Study

2010

338 citations

Penile cancer: is there an epidemiological role for smoking and sexual behaviour?

1987

151 citations

Penile cancer: is there an epidemiological role for smoking and sexual behaviour?

1987

151 citations

Male circumcision is associated with a lower prevalence of human papillomavirus‐associated penile lesions among Kenyan men

2011

55 citations

Male circumcision is associated with a lower prevalence of human papillomavirus‐associated penile lesions among Kenyan men

2011

55 citations

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers60

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

2008

25,031 citations

Cancer statistics, 2012

2012

10,655 citations

Optimal two-stage designs for phase II clinical trials

1989

3,494 citations

Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations

1999

1,653 citations

Cisplatin and Fluorouracil Alone or with Docetaxel in Head and Neck Cancer

2007

1,629 citations

Cisplatin, Fluorouracil, and Docetaxel in Unresectable Head and Neck Cancer

2007

1,612 citations

Male Circumcision, Penile Human Papillomavirus Infection, and Cervical Cancer in Female Partners

2002

813 citations

Trends in cancer risk among people with AIDS in the United States 1980–2002

2006

752 citations

Penile cancer: Importance of circumcision, human papillomavirus and smoking in in situ and invasive disease

2005

440 citations

Phase III Study Comparing Cisplatin Plus Fluorouracil to Paclitaxel, Cisplatin, and Fluorouracil Induction Chemotherapy Followed by Chemoradiotherapy in Locally Advanced Head and Neck Cancer

2005

440 citations

Systematic review of human papillomavirus prevalence in invasive penile cancer

2008

402 citations

EAU Penile Cancer Guidelines 2009

2010

394 citations

PATIENTS WITH PENILE CARCINOMA BENEFIT FROM IMMEDIATE RESECTION OF CLINICALLY OCCULT LYMPH NODE METASTASES

2005

348 citations

Penile cancer: epidemiology, pathogenesis and prevention

2008

342 citations

Recurrence Patterns of Squamous Cell Carcinoma of the Penis: Recommendations for Follow-Up Based on a Two-Centre Analysis of 700 Patients

2008

333 citations

Human papillomavirus prevalence and type distribution in penile carcinoma

2009

323 citations

Incidence trends in primary malignant penile cancer

2007

308 citations

Penile carcinoma: a challenge for the developing World

2004

270 citations

Preferential Association of Human Papillomavirus With High-Grade Histologic Variants of Penile-Invasive Squamous Cell Carcinoma

1995

245 citations

Lymphadenectomy in the Surgical Management of Penile Cancer

2009

234 citations

CISPLATIN, METHOTREXATE AND BLEOMYCIN FOR THE TREATMENT OF CARCINOMA OF THE PENIS: A SOUTHWEST ONCOLOGY GROUP STUDY

1999

225 citations

Surgical treatment of invasive squamous cell carcinoma of the penis: Brazilian national cancer institute long‐term experience

2008

214 citations

Edmonton symptom assessment scale: Italian validation in two palliative care settings

2005

195 citations

Pelvic Lymph Node Dissection for Penile Carcinoma: Extent of Inguinal Lymph Node Involvement as an Indicator for Pelvic Lymph Node Involvement and Survival

2007

185 citations

Human papillomavirus as a prognostic factor in carcinoma of the penis: analysis of 82 patients treated with amputation and bilateral lymphadenectomy.

2001

184 citations

Adjuvant and Neoadjuvant Vincristine, Bleomycin, And Methotrexate for Inguinal Metastases from Squamous Cell Carcinoma of the Penis

1988

179 citations

Sentinel Lymph Node Dissection for Penile Carcinoma: The M. D. Anderson Cancer Center Experience

1995

175 citations

Neoadjuvant Chemotherapy in Advanced Penile Carcinoma

2007

170 citations

Human Papillomavirus-16 Is the Predominant Type Etiologically Involved in Penile Squamous Cell Carcinoma

2007

169 citations

Neoadjuvant Chemotherapy Followed by Aggressive Surgical Consolidation for Metastatic Penile Squamous Cell Carcinoma

2007

167 citations

Advanced Penile Carcinoma

2003

164 citations

Taxanes in Combination with Cisplatin and Fluorouracil for Advanced Penile Cancer: Preliminary Results

2008

142 citations

Combination Chemotherapy with Methotrexate, Bleomycin and Cisplatin for Advanced Squamous Cell Carcinoma of the Male Genital Tract

1991

133 citations

Cisplatin and 5-Fluorouracil in Advanced Cancer of the Penis

1992

117 citations

A phase II multicentre study of irinotecan (CPT 11) in combination with cisplatin (CDDP) in metastatic or locally advanced penile carcinoma (EORTC PROTOCOL 30992)

2008

116 citations

Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas

1990

113 citations

Cisplatin, methotrexate and bleomycin for treating advanced penile carcinoma

2006

113 citations

Preoperative Lymphoscintigraphy and Dynamic Sentinel Node Biopsy for Staging Penile Cancer: Results With Pathological Correlation

2007

92 citations

Management of the Lymph Nodes in Penile Cancer

2010

91 citations

Paclitaxel in Pretreated Metastatic Penile Cancer: Final Results of a Phase 2 Study

2011

87 citations

COMBINATION CHEMOTHERAPY FOR METASTATIC OR LOCALLY ADVANCED GENITOURINARY SQUAMOUS CELL CARCINOMA: A PHASE II STUDY OF METHOTREXATE, CISPLATIN AND BLEOMYCIN

1998

87 citations

Cisplatin and 5‐fluorouracil in inoperable, stage IV squamous cell carcinoma of the penis

2012

86 citations

Cis-Diamminedichloroplatinum in the Treatment of Advanced Epidermoid Carcinoma of the Penis: A Southwest Oncology Group Study

1989

75 citations

Treatment of Visceral, Unresectable, or Bulky/Unresectable Regional Metastases of Penile Cancer

2010

62 citations

Long-Term Followup of Penile Carcinoma With High Risk for Lymph Node Invasion Treated With Inguinal Lymphadenectomy

2010

50 citations

Lymphoscintigraphy in penile cancer: limited value of sentinel node biopsy in patients with clinically suspicious lymph nodes

2006

43 citations

Feasibility and Activity of Sorafenib and Sunitinib in Advanced Penile Cancer: A Preliminary Report

2010

41 citations

Dynamic Sentinel Node Biopsy for Inguinal Lymph Node Staging in Patients with Penile Cancer: A Systematic Review and Cumulative Analysis of the Literature

2011

41 citations

Penile Carcinogenesis in a Low-Incidence Area

2011

35 citations

Adjuvant Treatment Using Bleomycin in Squamous Cell Carcinoma of Penis: Study of 19 Cases

1983

32 citations

Nodal Staging in Penile Carcinoma by Dynamic Sentinel Node Biopsy After Previous Therapeutic Primary Tumour Resection

2010

32 citations

18F-FDG PET/CT for monitoring induction chemotherapy in patients with primary inoperable penile carcinoma: first clinical results

2010

31 citations

Cisplatin and gemcitabine in the management of metastatic penile cancer

2008

30 citations

Human Papillomavirus Vaccination in Males: The State of the Science

2011

28 citations

Die aktuelle Situation der Chemotherapie des Peniskarzinoms

2009

25 citations

Chemotherapy for Penile and Urethral Carcinoma

2010

25 citations

Sentinel lymph node biopsy in penile cancer: evolution and insights.

2005

24 citations

Upregulation of nucleus HDGF predicts poor prognostic outcome in patients with penile squamous cell carcinoma bypass VEGF-A and Ki-67

2013

16 citations

Extended lymphadenectomy in penile cancer.