Back to search

Use of Nitrous Oxide Donor for Labor Induction in Women With PreEclampsia

NCT03171480

PHASE4INTERVENTIONAL
Ohio State University
176 participants
Started 2017-10-30 · Completed 2020-07-01
Status: Completed (as of 12-23-2025)

Conditions

PreeclampsiaLabor, Premature

Interventions

DRUG: Monoket PillDRUG: Placebo

Linked Papers (from SciSciNet-V2)

Total Papers5
Background
1
Result
0
Derived
0
Unknown
4
View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

A randomized controlled trial (RCT) of nitric-oxide donor (NOD) isosorbide mononitrate (IMN) versus placebo as an adjuvant to misoprostol/ intra-cervical Foley bulb for induction of labor to decrease rate of cesarean deliveries in pregnancies complicated by preeclampsia (≥24/0 weeks' gestation)

Sort by:

Background Papers1

Nitric oxide donors for cervical ripening and induction of labour
2016
59 citations

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers4

Pregnancy: Differential regulation of nitric oxide in the rat uterus and cervix during pregnancy and labour
1996
198 citations
Nitric oxide donors induce ripening of the human uterine cervix: a randomised controlled trial
1997
129 citations
Randomized trial of isosorbide mononitrate versus misoprostol for cervical ripening at term
2002
48 citations
Comparing vaginal misoprostol versus Foley catheter plus vaginal isosorbide mononitrate for labor induction
2015
11 citations