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The Acute Burn Resuscitation Multicenter Prospective Observational Trial

NCT03144427

NULLOBSERVATIONAL
American Burn Association
400 participants
Started 2017-02-24 · Completed 2021-07-15
Status: Completed (as of 12-23-2025)

Conditions

BurnsShock

Interventions

Linked Papers (from SciSciNet-V2)

Total Papers30
Background
7
Result
0
Derived
0
Unknown
23

Total Citations Per Year

Brief Summary

This is a prospective, non-interventional, observational study of consecutive burn patients admitted to 20 selected burn centers in North America. Primarily, data collection will be continuous "real-time" documentation of fluid infusion rates, vital signs and laboratory values of patients receiving fluid resuscitation during the first 48 hours following burn injury. All aspects of the resuscitation and all investigations performed will be according to the participating center's regular protocol, as this is purely an observational and non-interventional study. Further data collection on outcomes (organ function, ventilation duration, length of stay, and survival) will be collected at 72h, 96 h, and at hospital discharge.

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Background Papers14

Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma
2015
2,080 citations
Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma
2015
2,080 citations
The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study
2012
952 citations
The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study
2012
952 citations
The Association Between Fluid Administration and Outcome Following Major Burn
2007
254 citations
The Association Between Fluid Administration and Outcome Following Major Burn
2007
254 citations
Randomized Trial of Efficacy of Crystalloid and Colloid Resuscitation on Hemodynamic Response and Lung Water Following Thermal Injury
1983
218 citations
Randomized Trial of Efficacy of Crystalloid and Colloid Resuscitation on Hemodynamic Response and Lung Water Following Thermal Injury
1983
218 citations
Systemic and Pulmonary Hemodynamic Changes Accompanying Thermal Injury
1973
63 citations
Systemic and Pulmonary Hemodynamic Changes Accompanying Thermal Injury
1973
63 citations
Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study
2011
51 citations
Coordination and management of multicenter clinical studies in trauma: Experience from the PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study
2011
51 citations
Effect of Various Fluid Regimens and Pharmacologic Agents on the Circulatory Hemodynamics of the Immediate Postburn Period
1966
49 citations
Effect of Various Fluid Regimens and Pharmacologic Agents on the Circulatory Hemodynamics of the Immediate Postburn Period
1966
49 citations

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers23

PHYSIOLOGICAL RESPONSE TO CRYSTALLOID RESUSCITATION OF SEVERE BURNS
1968
497 citations
The Phenomenon of “Fluid Creep” in Acute Burn Resuscitation
2007
305 citations
Release of Abdominal Compartment Syndrome Improves Survival in Patients with Burn Injury
2002
170 citations
A Biopsy of the Use of the Baxter Formula to Resuscitate Burns or Do We Do It Like Charlie Did It?
2000
155 citations
Predicting Increased Fluid Requirements During the Resuscitation of Thermally Injured Patients
2004
155 citations
How Well Does The Parkland Formula Estimate Actual Fluid Resuscitation Volumes?
2002
147 citations
Colloid Administration Normalizes Resuscitation Ratio and Ameliorates “Fluid Creep”
2010
133 citations
Fluid Creep: The Pendulum Hasnʼt Swung Back Yet!
2010
127 citations
Role of thermal injury-induced hypoproteinemia on fluid flux and protein permeability in burned and nonburned tissue.
1984
94 citations
The PRospective Observational Multicenter Major Trauma Transfusion (PROMMTT) study
2013
88 citations
Fluid and Electrolyte Replacement in the Burned Patient
1978
88 citations
Studies in shock and resuscitation, I: use of a hypertonic, albumin-containing, fluid demand regimen (HALFD) in resuscitation.
1979
85 citations
Five percent albumin for adult burn shock resuscitation: lack of effect on daily multiple organ dysfunction score
2005
81 citations
Colloid Normalizes Resuscitation Ratio in Pediatric Burns
2010
67 citations
Acute Respiratory Failure That Complicates the Resuscitation of Pediatric Patients With Scald Injuries
1999
62 citations
Effect of nonprotein colloid on postburn edema formation in soft tissues and lung.
1984
62 citations
Early albumin use improves mortality in difficult to resuscitate burn patients
2012
60 citations
The burn patient: II. Later care and complications of thermal injury
1979
56 citations
A Review of the Use of Human Albumin in Burn Patients
2012
49 citations
Fluid resuscitation of burn patients comparing a crystalloid with a colloid containing solution: a prospective study.
1975
31 citations
Fluid and electrolyte therapy of burn shock.
1973
29 citations
Thermal skin injury: Effect of fluid therapy on the transcapillary colloid osmotic gradient
1991
23 citations
Untitled
— citations