Oxytocin Intranasal Administrations in Children With Prader-Willi Syndrome Aged From 3 to 12 Years

NCT03114371

NAINTERVENTIONAL

University Hospital, Toulouse

40 participants

Started 2016-11-28 · Completed 2019-01-11

Status: Completed (as of 12-23-2025)

Conditions

Prader-Willi Syndrome

Interventions

DRUG: Oxytocin DRUG: Placebo DRUG: Oxytocin

Linked Papers (from SciSciNet-V2)

Total Papers21

Background

6

Result

0

Derived

0

Unknown

15

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

Positive results in preclinical and clinical studies in adults and infants with Prader-Willi syndrome lead investigators to set up a new study in children with Prader-Willi syndrome. The objective of this study is to document effects of oxytocin intranasal administrations on behavioural troubles in children with Prader-Willi syndrome aged from 3 to 12 years.

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Background Papers12

Nutritional phases in Prader–Willi syndrome

Nutritional phases in Prader–Willi syndrome

The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial

The effect of oxytocin nasal spray on social interaction deficits observed in young children with autism: a randomized clinical crossover trial

Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome

Effects of intranasal oxytocin on social anxiety in males with fragile X syndrome

Prader–Willi syndrome and autism spectrum disorders: an evolving story

Prader–Willi syndrome and autism spectrum disorders: an evolving story

Oxytocin may be useful to increase trust in others and decrease disruptive behaviours in patients with Prader-Willi syndrome: a randomised placebo-controlled trial in 24 patients

Oxytocin may be useful to increase trust in others and decrease disruptive behaviours in patients with Prader-Willi syndrome: a randomised placebo-controlled trial in 24 patients

Whole genome microarray analysis of gene expression in Prader–Willi syndrome

Whole genome microarray analysis of gene expression in Prader–Willi syndrome

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers15

Oxytocin increases trust in humans

3,586 citations

Testing the Efficiency and Independence of Attentional Networks

3,505 citations

Intranasal Oxytocin Improves Emotion Recognition for Youth with Autism Spectrum Disorders

Intergenerational transmission of subthreshold autistic traits in the general population

Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases.

A review of safety, side-effects and subjective reactions to intranasal oxytocin in human research

The effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: a randomized controlled trial

A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

Oxytocin increases amygdala reactivity to threatening scenes in females

Assessment of Hyperphagia in Prader‐Willi Syndrome

A double‐blind randomized controlled trial of oxytocin nasal spray in Prader Willi syndrome

Appetite hormones and the transition to hyperphagia in children with Prader-Willi syndrome

Problem Behaviors and Personality of Children and Adolescents With Prader-Willi Syndrome

Mental health problems in children with prader-willi syndrome.

The Sentence Completion and Three Wishes tasks: windows into the inner lives of people with intellectual disabilities