Effect of Steroids on Post-tonsillectomy Morbidities

NCT02401529

PHASE2INTERVENTIONAL

King Fahd General Hospital

100 participants

Started 2013-01 · Completed 2014-03

Status: Completed (as of 12-23-2025)

Conditions

Postoperative PainPostoperative Nausea and Vomiting

Interventions

DRUG: IV dexamethasone DRUG: Oral prednisolone DRUG: Paracetamol DRUG: IV saline

Linked Papers (from SciSciNet-V2)

Total Papers23

Background

2

Result

0

Derived

0

Unknown

21

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

This study aims to evaluate the effect of postoperative systemic rapid onset and short acting dexamethasone followed by a tapering dose of oral prednisolone on post-tonsillectomy morbidities. Half of the patients who comply with the inclusion criteria were selected to receive a single postoperative dose of intravenous dexamethasone followed by oral steroids; the second group received placebo.

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Background Papers4

Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion

Nausea in cancer chemotherapy is inversely related to urinary cortisol excretion

The Effect of Intravenous Dexamethasone and Lidocaine on Propofol-Induced Vascular Pain: A Randomized Double-Blinded Placebo-Controlled Trial

The Effect of Intravenous Dexamethasone and Lidocaine on Propofol-Induced Vascular Pain: A Randomized Double-Blinded Placebo-Controlled Trial

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers21

Dexamethasone for the Prevention of Postoperative Nausea and Vomiting: A Quantitative Systematic Review

Dexamethasone reduces pain and swelling following extraction of third molar teeth

Pain as a major cause of postoperative nausea

Guidelines for Antiemetic Treatment of Chemotherapy-Induced Nausea and Vomiting: Past, Present, and Future Recommendations

Dexamethasone reduces postoperative vomiting and pain after pediatric tonsillectomy

The effect of methlyprednisolone on pain, trismus, and swelling after removal of third molars

Methylprednisolone as an antiemetic during cancer chemotherapy—a pilot study

Comparison of two methods of tonsillectomy

CYTOTOXIC-THERAPY-INDUCED VOMITING IS MEDIATED VIA ENKEPHALIN PATHWAYS

Epidural dexamethasone reduces postoperative pain and analgesic requirements

The effect of preoperative dexamethasone on early oral intake, vomiting and pain after tonsillectomy

Safety of High-Dose Corticosteroids for the Treatment of Autoimmune Inner Ear Disease

Prophylaxis for Vomiting by Children After Tonsillectomy

Use of intravenous steroids at induction of anaesthesia for adult tonsillectomy to reduce post‐operative nausea and vomiting and pain: a double‐blind randomized controlled trial

Effects of oral prednisolone on recovery after tonsillectomy

The effect of dexamethasone on postoperative vomiting and oral intake after adenotonsillectomy

Postoperative dental pain--a comparative study of anti-inflammatory and analgesic agents.

Post-tonsillectomy pain and vomiting:role of pre-operative steroids.

Effect of Dexamethasone on Nausea, Vomiting, and Pain in Paediatric Tonsillectomy

Vomiting post tonsillectomy at the University Hospital of the West Indies