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Analysis of Tumor Tissue and Circulating Genetic Material in the Blood to Obtain Further Insight in the Effectiveness of Everolimus When Combined With Exemestane
NCT02109913
NAINTERVENTIONAL
Amsterdam UMC, location VUmc
175 participants
Started 2014-03 · Completed 2021-01
Status: Unknown (as of 12-23-2025)
Conditions
Hormone Receptor Positive Malignant Neoplasm of BreastMetastatic Breast Cancer
Interventions
Linked Papers (from SciSciNet-V2)
Total Papers3
Background
3Result
0Derived
0Unknown
0Total Citations Per Year
Brief Summary
The purpose of this study is to determine whether biomarkers could be found to gain more insight in tumor characteristics in order to predict which patients will have a high chance of a long progression-free survival. Postmenopausal patients with advanced metastatic breast cancer who have progressed on anastrozole or letrozole will be eligible for this study.
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Background Papers6
Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer
2011
2,616 citations
Everolimus in Postmenopausal Hormone-Receptor–Positive Advanced Breast Cancer
2011
2,616 citations
Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis
2013
461 citations
Everolimus Plus Exemestane in Postmenopausal Patients with HR+ Breast Cancer: BOLERO-2 Final Progression-Free Survival Analysis
2013
461 citations
The Phosphoinositide-3-Kinase-Akt-mTOR Pathway as a Therapeutic Target in Breast Cancer
2013
105 citations
The Phosphoinositide-3-Kinase-Akt-mTOR Pathway as a Therapeutic Target in Breast Cancer
2013
105 citations
Result Papers0
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Unknown Papers0
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