Oxytocin Effects on Cardiac Electrophysiology

NCT01780337

EARLY_PHASE1INTERVENTIONAL

William Whang

12 participants

Started 2013-01 · Completed 2016-05

Status: Completed (as of 12-23-2025)

Conditions

Cardiac Arrhythmia

Interventions

DRUG: Oxytocin OTHER: Saline

Linked Papers (from SciSciNet-V2)

Total Papers14

Background

3

Result

0

Derived

0

Unknown

11

View on ClinicalTrials.gov

Total Citations Per Year

Brief Summary

In this pilot study the investigators will perform a double-blind randomized trial of intranasal oxytocin on measures of cardiac refractoriness, among individuals who are undergoing clinically indicated catheter ablation procedures for paroxysmal atrial fibrillation. The investigators seek to enroll 20 patients for this study, for the purpose of estimating effect sizes for a larger future study.

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Background Papers6

Heart disease and stroke statistics--2012 update: a report from the American Heart Association.

6,982 citations

Heart disease and stroke statistics--2012 update: a report from the American Heart Association.

6,982 citations

Depression and Risk of Sudden Cardiac Death and Coronary Heart Disease in Women

Depression and Risk of Sudden Cardiac Death and Coronary Heart Disease in Women

Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation

Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation

Result Papers0

No result papers linked

Derived Papers0

No derived papers linked

Unknown Papers11

Sudden Cardiac Death in the United States, 1989 to 1998

1,583 citations

Depression, Heart Rate Variability, and Acute Myocardial Infarction

A review of safety, side-effects and subjective reactions to intranasal oxytocin in human research

Low Heart Rate Variability and the Effect of Depression on Post–Myocardial Infarction Mortality

Depression as a predictor for appropriate shocks among patients with implantable cardioverter-defibrillators

Implantable Defibrillators and Sudden Cardiac Death

Oxytocin increases autonomic cardiac control: Moderation by loneliness

Depression and Risk of Sudden Cardiac Death After Acute Myocardial Infarction: Testing for the Confounding Effects of Fatigue

Clinical Depression and Risk of Out-of-Hospital Cardiac Arrest

Cardiac effects of synthetic oxytocin (Syntocinon)