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The Effect of Rosiglitazone on Ischemia-reperfusion-injury Using Annexin A5 Scintigraphy.
NCT00405015
PHASE2INTERVENTIONAL
Radboud University Medical Center
13 participants
Started 2007-04 · Completed 2008-10
Status: Completed (as of 12-23-2025)
Conditions
Ischemia-Reperfusion InjuryThe Metabolic Syndrome
Interventions
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Brief Summary
Cardiovascular disease is the leading cause of death in diabetic patients due to both a high event rate and a worse outcome. A pharmacological intervention that reduces ischemia-reperfusion-injury would improve the outcome of diabetic patients after a cardiovascular event. In the present study, we will use annexinA5 scintigraphy to address the following hypothesis: Rosiglitazone reduces ischemia-reperfusion-injury in humans with insulin resistance.
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Diabetes and Cardiovascular Disease
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2005
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Annexin A5 Scintigraphy of Forearm as a Novel In Vivo Model of Skeletal Muscle Preconditioning in Humans
2004
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