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Study Comparing Outcomes for Patients With Treatment Resistant Depression Who Receive VNS Therapy at Different Doses
NCT00305565
PHASE4INTERVENTIONAL
Cyberonics, Inc.
331 participants
Started 2006-01 · Completed 2010-02
Status: Completed (as of 12-23-2025)
Conditions
Depression
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Brief Summary
This is a postmarket medical device study. The objective of this study is to compare the safety and effectiveness of Vagus Nerve Stimulation (VNS) Therapy administered at different amounts of electrical charge for the treatment of patients with treatment-resistant depression (TRD).
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The Epidemiology of Major Depressive Disorder
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Vagus Nerve Stimulation for Treatment-Resistant Depression: A Randomized, Controlled Acute Phase Trial
2005
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Effects of 12 Months of Vagus Nerve Stimulation in Treatment-Resistant Depression: A Naturalistic Study
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A One-Year Comparison of Vagus Nerve Stimulation with Treatment as Usual for Treatment-Resistant Depression
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