A model for chromatin opening: stimulation of topoisomerase II and restriction enzyme cleavage of chromatin by distamycin.

Chromosomal Subunits in Active Genes Have an Altered Conformation

1976 • 1,842 citations

Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin.

1979 • 1,532 citations

NUCLEASE HYPERSENSITIVE SITES IN CHROMATIN

1988 • 1,233 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

DNA bending at adenine · thymine tracts

1986 • 1,032 citations

Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites

1986 • 922 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure.

1990 • 674 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Metaphase chromosome structure

1986 • 538 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

Alternative chromatin structure at CpG islands

1990 • 480 citations

The chromatin structure of specific genes: I. Evidence for higher order domains of defined DNA sequence

1979 • 445 citations

MOLECULAR ARRANGEMENT AND EVOLUTION OF HETEROCHROMATIC DNA

1980 • 412 citations

Higher order metaphase chromosome structure: Evidence for metalloprotein interactions

1982 • 398 citations

The formation and function of DNase I hypersensitive sites in the process of gene activation.

1988 • 394 citations

Chromosome assembly in vitro: Topoisomerase II is required for condensation

1991 • 382 citations

Map of distamycin, netropsin, and actinomycin binding sites on heterogeneous DNA: DNA cleavage-inhibition patterns with methidiumpropyl-EDTA.Fe(II).

1982 • 332 citations

Preferential, cooperative binding of DNA topoisomerase II to scaffold-associated regions.

1989 • 317 citations

The transcriptional regulation of Xenopus 5S RNA genes in chromatin: The roles of active stable transcription complexes and histone H1

1984 • 265 citations

Alternative processing of mRNAs encoding mammalian chromosomal high-mobility-group proteins HMG-I and HMG-Y.

1989 • 241 citations

Drosophilatopoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site

1985 • 239 citations

Visualization of the bent helix in kinetoplast DNA by electron microscopy

1986 • 226 citations

Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous DNA. Footprinting with methidiumpropyl-EDTA.cntdot.iron(II)

1983 • 218 citations

DNA structural variations produced by actinomycin and distamycin as revealed by DNAase I footprinting

1984 • 205 citations

Curvature of mouse satellite DNA and condensation of heterochromatin

1987 • 192 citations

Dominant and specific repression of Xenopus oocyte 5S RNA genes and satellite I DNA by histone H1.

1989 • 188 citations

Nucleosomes: regulators of transcription

1990 • 186 citations

In vivo topoisomerase II cleavage of the Drosophila histone and satellite III repeats: DNA sequence and structural characteristics.

1992 • 181 citations

Chromatin structure of transcriptionally competent and repressed genes.

1990 • 178 citations

Highly preferential nucleation of histone H1 assembly on scaffold-associated regions

1989 • 165 citations

Salt-dependent co-operative interaction of histone H1 with linear DNA

1986 • 142 citations

Solution structure of the chromomycin-DNA complex

1989 • 138 citations

Specific inhibition of DNA Binding to nuclear scaffolds and histone H1 by distamycin

1989 • 137 citations

Scaffold attachment of DNA loops in metaphase chromosomes

1988 • 137 citations

A complex of interacting DNAase I-hypersensitive sites near the drosophila glue protein gene, Sgs4

1982 • 126 citations

Sequence and sequence variation within the 1.688 g/cm3 satellite DNA of Drosophila melanogaster

1979 • 121 citations

Histone H1 and the regulation of transcription of eukaryotic genes

1990 • 117 citations

A DNA binding protein that recognizes oligo(dA).oligo(dT) tracts.

1989 • 117 citations

Protein D1 preferentially binds A + T-rich DNA in vitro and is a component of Drosophila melanogaster nucleosomes containing A + T-rich satellite DNA.

1982 • 111 citations

Presence of histone H1 on an active Balbiani ring gene

1990 • 101 citations

The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species.

1986 • 97 citations

Investigations into the sequence-selective binding of mithramycin and related ligands to DNA

1985 • 96 citations

Histone H1 represses transcription from minichromosomes assembled in vitro.

1989 • 92 citations

Alternative Processing of mRNAs Encoding Mammalian Chromosomal High-Mobility-Group Proteins HMG-I and HMG-Y

1989 • 84 citations

Cross‐linking of Histone H1 in Chromatin

1980 • 78 citations

Improved methods for the isolation of individual and clustered mitotic chromosomes

1987 • 72 citations

Generation of different nucleosome spacing periodicities in vitro

1988 • 55 citations

Chromatin fine structure of the histone gene complex ofDrosophila melanogaster

1983 • 54 citations

The arrangement of H5 molecules in extended and condensed chicken erythrocyte chromatin.

1985 • 48 citations

Preferential and cooperative binding of histone I to chromosomal mammalian DNA.

1975 • 44 citations

Histone H5 can correctly align randomly arranged nucleosomes in a defined in vitro system

1983 • 42 citations

Influence of DNA-binding drugs on chromatin condensation

1986 • 40 citations

Histone H1 Represses Transcription from Minichromosomes Assembled In Vitro

1989 • 33 citations

Two puff-specific proteins bind within the 2.5 kb upstream region of theDrosophila melanogaster Sgs-4 gene

1990 • 32 citations

Formation and characterization of soluble complexes of histone H1 with supercoiled DNA

1986 • 31 citations

The Drosophila melanogaster Actin 5C Gene Uses Two Transcription Initiation Sites and Three Polyadenylation Sites To Express Multiple mRNA Species

1986 • 28 citations

Histone H5 can increase the internucleosome spacing in dinucleosomes to native-like values

1983 • 24 citations