Hypomethylation of c-myc and epidermal growth factor receptor genes in human hepatocellular carcinoma and fetal liver.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

1983 • 2,392 citations

DNA Methylation and Gene Function

1980 • 2,069 citations

Hypomethylation of DNA from Benign and Malignant Human Colon Neoplasms

1985 • 844 citations

The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes

1981 • 736 citations

Integration of Hepatitis B Virus DNA into the Genome of Liver Cells in Chronic Liver Disease and Hepatocellular Carcinoma

1981 • 715 citations

MspI, an isoschizomer of HpaII which cleaves both unmethylated and methylated HpaII sites

1978 • 395 citations

C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment

1984 • 362 citations

Cloning and characterization of different human sequences related to the onc gene (v-myc) of avian myelocytomatosis virus (MC29).

1982 • 348 citations

Human epidermal growth factor receptor cDNA is homologous to a variety of RNAs overproduced in A431 carcinoma cells

1984 • 296 citations

Expression of a Cellular Oncogene During Liver Regeneration

1983 • 281 citations

Human DNA sequence homologous to the transforming gene (mos) of Moloney murine sarcoma virus.

1982 • 193 citations

Oncogene Expression in Liver Regeneration and Hepatocarcinogenesis

2007 • 121 citations

DNA methylation pattern is determined by the intracellular level of the methylase.

1984 • 72 citations