[34] The prospects for carbon-13 nuclear magnetic resonance studies in enzymology

The Principles of Nuclear Magnetism

1961 • 14,411 citations

Data Reduction and Error Analysis for the Physical Sciences

1969 • 13,865 citations

An algorithm for the machine calculation of complex Fourier series

1965 • 11,350 citations

Relaxation Effects in Nuclear Magnetic Resonance Absorption

1948 • 6,241 citations

Spin Echoes

1950 • 4,669 citations

An efficient method for finding the minimum of a function of several variables without calculating derivatives

1964 • 4,391 citations

The principles of nuclear magnetism

1961 • 4,252 citations

Nuclear Induction

1946 • 3,230 citations

Relaxation Processes in a System of Two Spins

1955 • 3,133 citations

NMR Basic principles and progress

1973 • 2,080 citations

Application of Fourier Transform Spectroscopy to Magnetic Resonance

1966 • 1,607 citations

Introduction to Magnetic Resonance

1967 • 1,564 citations

The Theory of Relaxation Processes

1965 • 1,464 citations

Pulse and Fourier Transform NMR

1971 • 1,310 citations

Measurement of Spin Relaxation in Complex Systems

1968 • 1,242 citations

The Nuclear Induction Experiment

1946 • 1,164 citations

Proton Relaxation Times in Paramagnetic Solutions

1957 • 1,017 citations

Technique of organic chemistry

1970 • 985 citations

Theory of Isotropic Hyperfine Interactions in π-Electron Radicals

1958 • 897 citations

Nuclear Spin Relaxation in Ellipsoids Undergoing Rotational Brownian Motion

1962 • 891 citations

Spin Relaxation Processes in a Two-Proton System Undergoing Anisotropic Reorientation

1962 • 865 citations

Carbon-13 Magnetic Resonance. II. Chemical Shift Data for the Alkanes

1964 • 781 citations

CHEMICAL SHIFTS IN THE NUCLEAR MAGNETIC RESONANCE SPECTRA OF MOLECULES CONTAINING POLAR GROUPS

1960 • 725 citations

Polyamino Acids, Polypeptides and Proteins

1964 • 675 citations

Tertiary Structure of Ribonuclease

1967 • 573 citations

Molecular orbital theory of nuclear spin coupling constants

1964 • 554 citations

Proton Magnetic Resonance of Hydrocarbons

1956 • 532 citations

The Three-Dimensional Structure of Ribonuclease-S

1970 • 510 citations

Sensitivity Enhancement in Magnetic Resonance

1966 • 480 citations

Segmental flexibility in an antibody molecule

1970 • 465 citations

Theory of Nuclear Overhauser Enhancement and C13–1H Dipolar Relaxation in Proton-Decoupled Carbon-13 NMR Spectra of Macromolecules

1972 • 450 citations

Free-Induction Decays in Solids

1957 • 433 citations

Substituent Effects on the C13 and H1 Chemical Shifts in Monosubstituted Benzenes

1961 • 415 citations

Natural Abundance Carbon-13 Partially Relaxed Fourier Transform Nuclear Magnetic Resonance Spectra of Complex Molecules

1971 • 413 citations

Carbon-13 magnetic resonance. IX. Methylcyclohexanes

1967 • 406 citations

Magnetic Resonance in Biological Systems

1967 • 362 citations

Effect of Internal Rotation on Angular Correlation Functions

1967 • 343 citations

Nuclear magnetic resonance spectroscopy. Carbon-13 chemical shifts in acyclic and alicyclic alcohols

1970 • 317 citations

Molecular Associations in Biology

1968 • 313 citations

Nuclear Overhauser Effects and 13C Relaxation Times in 13C–{H} Double Resonance Spectra

1970 • 267 citations

Nuclear Magnetic Resonance Spectroscopy of Amino Acids, Peptides, and Proteins

1970 • 257 citations

Proton magnetic resonance spectra of proteins in random-coil configurations

1969 • 251 citations

Hydrogen Ion Equilibria of Ribonuclease¹

1956 • 249 citations

Carbon-13 magnetic resonance studies of amino acids and peptides

1968 • 224 citations

Electronic structure of cyanide complexes of hemes and heme proteins

1971 • 211 citations

The Study of Anisotropic Rotation of Molecules in Liquids by NMR Quadrupolar Relaxation

1970 • 208 citations

Manifestations of the tertiary structures of proteins in high-frequency nuclear magnetic resonance

1967 • 201 citations

Comments on ``Proton Relaxation Times in Paramagnetic Solutions''

1957 • 195 citations

C¹³ Nuclear Magnetic Resonance Spectroscopy. I. Aromatic Hydrocarbons

1961 • 188 citations

Carbon-13 magnetic resonance. VIII. Theory of carbon-13 chemical shifts applied to saturated hydrocarbons

1967 • 179 citations

Conformation and segmental motion of native and denatured ribonuclease A in solution. Application of natural-abundance carbon-13 partially relaxed Fourier transform nuclear magnetic resonance

1971 • 175 citations

Carbon-13 magnetic resonance. X. Six-membered nitrogen heterocycles and their cations

1968 • 173 citations

Carbon-13 magnetic resonance studies of amino acids and peptides. II

1970 • 172 citations

Nuclear magnetic resonance studies of the structure and binding sites of enzymes

1969 • 171 citations

Electronic structure of the α-amino acids of proteins

1963 • 171 citations

The Nuclear Magnetic Resonance of Some Paramagnetic Transition Metal Acetylacetonates

1965 • 166 citations

Nuclear Magnetic Relaxation Study of Intermolecular Complexes. The Mechanism of Penicillin Binding to Serum Albumin^1a

1965 • 165 citations

Carbon—Carbon Spin-Coupling Constants in Characteristic CC-Bond Types

1963 • 165 citations

¹³C N.M.R. STUDIES: PART III. CARBON-13 N.M.R. SPECTRA OF SUBSTITUTED ACETOPHENONES

1965 • 160 citations

Nuclear magnetic resonance spectroscopy. Benzene-13C

1967 • 148 citations

Magnetic Resonance Studies of Macromolecules. I. Aromatic-Methyl Interactions and Helical Structure Effects in Lysozyme^*

1967 • 145 citations

Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of aliphatic carboxylic acids and carboxylate anions

1969 • 144 citations

C¹³ CHEMICAL SHIFTS IN ORGANIC CARBONYL GROUPS

1964 • 143 citations

The Identification of a Glutamic Acid Residue as Part of the Active Site of Ribonuclease T1

1967 • 137 citations

Carbon-13 magnetic resonance. XIX. Benzimidazole, purine, and their anionic and cationic species

1971 • 136 citations

Nuclear magnetic resonance spectroscopy. Carbon-13 chemical shifts of small peptides as a function of pH

1972 • 134 citations

Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of five-membered aromatic heterocycles

1968 • 127 citations

Carbon-13 Chemical Shifts of the Carbonyl Group. III. Solvent Effects

1965 • 126 citations

Nuclear magnetic resonance studies of the structure and binding sites of enzymes. VII. Solvent and temperature effects on the ionization of histidine residues of ribonuclease

1969 • 121 citations

Nuclear magnetic resonance study of the mechanism of reversible denaturation of lysozyme

1971 • 119 citations

Carbon-13 Fourier Transform Nuclear Magnetic Resonance. X. Effect of Molecular Weight on 13C Spin-Lattice Relaxation Times of Polystyrene in Solution

1972 • 113 citations

Dissoziationsgleichgewichte von Glutathion

1972 • 112 citations

Spin–Lattice Relaxation in High-Resolution NMR Spectra of Carbon-13

1970 • 111 citations

Segmental motion in liquid 1-decanol. Application of natural-abundance carbon-13 partially relaxed Fourier transform nuclear magnetic resonance

1971 • 111 citations

Additivity Relationships in Carbon-13 Chemical Shift Data for the Linear Alkanes

1963 • 102 citations

Proton Magnetic Resonance of Proteins Fully Deuterated except for ¹ H-Leucine Side Chains

1968 • 102 citations

Carbon-13 magnetic resonance. XII. Five-membered nitrogen heterocycles and their charged species

1968 • 99 citations

Carbon-13 nuclear magnetic resonance spectroscopy of naturally occurring substances. I. Direct analysis of nonprotonated carbon centers

1969 • 99 citations

Alternately pulsed carbon-13 and proton magnetic resonance, an alternative to nuclear off-resonance decoupling

1971 • 98 citations

Theory of Nuclear Spin-Spin Coupling

1965 • 98 citations

Conformational States of Bovine Pancreatic Ribonuclease A Observed by Normal and Partially Relaxed Carbon 13 Nuclear Magnetic Resonance

1972 • 97 citations

Magnetic deshielding of protons due to intramolecular steric interactions with proximate hydrogens

1968 • 96 citations

Solvent Effects on the C¹³ Chemical Shift of the Carbonyl Group of Acetone

1963 • 94 citations

Nuclear magnetic resonance determination of ligand-induced conformational changes in myoglobin

1970 • 92 citations

Temperature-dependent carbon-13 relaxation studies of small molecules

1972 • 91 citations

The Carbon-13 Nuclear Magnetic Resonance Spectra of Furan, Pyrrole, Thiophene, and Some of Their Methyl Derivatives^1a

1965 • 87 citations

A molecular orbital theory of hydrocarbons

1965 • 84 citations

Spin-rotation interaction and anisotropic chemical shift in 13CS2

1971 • 82 citations

Proton Magnetic Resonance Spectra of Some Proteins

1965 • 81 citations

Carbon-13 Chemical Shifts of Vinyl Carbons

1965 • 76 citations

Fundamentals of Nuclear Magnetic Resonance Absorption. I

1950 • 76 citations

Carbon 13 Nuclear Magnetic Resonance of Peptides in the Amino-terminal Sequence of Sperm Whale Myoglobin

1971 • 75 citations

The interpretation of carbon nuclear magnetic resonance shifts

1971 • 75 citations

Perturbation of the PMR spectrum of lysozyme by Co+2

1969 • 72 citations

Nuclear spin–spin coupling between directly bound elements

1969 • 68 citations

Field-dependent contributions to carbon-13 nuclear relaxation

1971 • 67 citations

On the mechanism of the binding of sulfonamides to bovine serum albumin.

1965 • 65 citations

Pulse Fourier Transform ¹³C‐NMR Spectroscopy, Principles and Applications

1971 • 64 citations

Carbon-13 nuclear magnetic resonance studies of heterogeneous systems. Amino acids bound to cationic exchange resins

1971 • 62 citations

Carbon magnetic resonance studies of enriched compounds. Carbon-13-carbon-13 coupling constants of 13C-7 labeled monosubstituted benzene derivatives

1972 • 58 citations

Carbon-13 magnetic resonance. Phenyllithium and phenylmagnesium bromide

1969 • 58 citations

Carbon-13 Chemical Shifts of the Carbonyl Group. II. A Correlation with CO Pi-Bond Polarity

1965 • 57 citations

Nuclear magnetic resonance studies of the bonding in aromatic systems. Correlation of Hammett sigma constants with methyl13C-H coupling constants and chemical shifts

1969 • 55 citations

Assignment of tryptophan indole NH proton resonances of lysozyme

1969 • 55 citations

Nuclear magnetic resonance spectroscopy. Carbon-carbon coupling in cyclopropane derivatives

1967 • 54 citations

Chemical shift calculations for carbon, nitrogen and oxygen in simple molecules

1970 • 53 citations

The Nature of the Complexities in the Ribonuclease Conformational Transition and the Implications Regarding Clathrating

1965 • 49 citations

Carbon-13 Chemical Shifts of the Carbonyl Group. IV. Dilution Curves for Acetic Acid in Representative Solvents^1-3

1966 • 49 citations

13C Nuclear Magnetic Resonance Spectrum of Gramicidin S-A, a Decapeptide Antibiotic

1970 • 48 citations

Dipolar contributions to carbon-13 relaxation times

1971 • 46 citations

High Resolution Proton Magnetic Resonance Studies of Cyanoferrimyoglobins and Alkylated Derivatives from Different Species

1970 • 45 citations

Effect of polar substituents upon carbon-13-carbon-13 coupling constants

1967 • 45 citations

Biosynthetic studies with carbon-13. Asperlin

1971 • 45 citations

Effect of CH scalar coupling on carbon-13 transverse relaxation times

1971 • 43 citations

Nuclear magnetic relaxation in polymer solutions

1970 • 40 citations

Carbon-13 magnetic resonance. XVI. Chemical shifts in acepleiadiene and acepleiadylene

1970 • 39 citations

Carbon-13 intensity problem. Elimination of the Overhauser effect with an added paramagnetic species

1971 • 38 citations

CARBON-13 CHEMICAL SHIFTS OF para-DISUBSTITUTED BENZENES

1963 • 38 citations

Nuclear magnetic resonance spectroscopy. Use of carbon-13 isotropic shifts as a probe of mechanisms of spin transmission in metal complexes. Some pyridine-type bases and triphenylphosphine complexed to nickel(II) and cobalt(II) acetylacetonates

1970 • 38 citations

Average-Excitation-Energy Approximation in the Calculation of Carbon-13 Chemical Shifts of Nitrogen Heterocyclics

1969 • 38 citations

¹³C n.m.r. studies. X. ¹³C spectra of some substituted methyl benzoates

1967 • 37 citations

Carbon-13 Chemical Shifts and Intramolecular Hydrogen Bonding

1964 • 36 citations

Protection of Peptides of Biological Origin for Use as Intermediates in the Chemical Synthesis of Proteins

1969 • 35 citations

Carboxymethylation of Sperm Whale Myoglobin in the Dissolved State

1970 • 35 citations

A Relationship between the Carbon-13 Carbonyl Chemical Shifts and n → π^* Transition Energies in Cyclic and Bicyclic Ketones

1965 • 34 citations

Carbon magnetic resonance. Signal assignment by alternately pulsed nuclear magnetic resonance and lanthanide-induced chemical shifts

1971 • 34 citations

Study of Some Cyano-Metal Complexes by Nuclear Magnetic Resonance. I. Chemical Shifts and Line Widths of N¹⁴ and C¹³ Resonances

1965 • 33 citations

Carbon−13 NMR of Paramagnetic Iron-Group Cyanides

1967 • 32 citations

Carbon-13 Fourier transform nuclear magnetic resonance studies of peptides

1971 • 32 citations

Carbon-13 Fourier transform nuclear magnetic resonance study of some porphyrins. Evidence for a preferred delocalization pathway

1972 • 32 citations

¹³C Nuclear Magnetic Resonance Spectra of Proteins

1970 • 31 citations

Natural abundance ¹³C spectra of proteins: Carboxy‐myoglobin and hemoglobin

1971 • 29 citations

Nuclear Magnetic Resonance

1970 • 29 citations

Protected Intermediate for the Preparation of Semisynthetic Insulins

1970 • 26 citations

Carbon-13 magnetic resonance studies of carbon-13 enriched amino acids

1969 • 26 citations

Carbon 13 Nuclear Magnetic Resonance Spectroscopy of Myoglobins and Ribonuclease A Carboxymethylated with Enriched [2-13C]Bromoacetate

1972 • 26 citations

Studies of 13C13C coupling constants. III. Ethyl compounds

1971 • 26 citations

Fourier Transform ¹³C‐NMR Spectroscopy of Biologically Active Cysteine Peptides

1970 • 25 citations

Anisotropy of the Carbon Chemical Shift in Methyl Iodide

1967 • 24 citations

Use of carbon-13 nuclear magnetic resonance (Cmr) spectroscopy in biosynthetic studies. Incorporation of carboxyl and methyl carbon-13 labeled acetates into cephalosporin C

1971 • 24 citations

Systematic analysis of chemical shifts in the nuclear magnetic resonance spectra of peptide chains. II. Oligoglycines

1968 • 24 citations

Carbon-13 nuclear magnetic resonance spectroscopy of naturally occurring substances. VI. Structure analysis by carbon-13 nuclear magnetic resonance spectroscopy. Arenaine

1971 • 24 citations

¹³C Nuclear magnetic resonance studies. XIV. Conformational effects on carbinyl carbon shieldings in cyclohexanols and derivatives

1969 • 23 citations

Natural Abundance Fourier Transform of 13C Nuclear Magnetic Resonance Spectra of Lysozyme

1971 • 23 citations

Conformational Studies by Low Temperature ¹³C‐NMR Spectroscopy

1971 • 20 citations

Carbon-13 Nuclear Magnetic Resonance Spectroscopy: Carbon-13 Chemical Shifts and Coupling Constants

1969 • 20 citations

LINE WIDTHS OF PROTON MAGNETIC RESONANCE SPECTRA OF PROTEINS IN SOLUTION

1971 • 19 citations

Spin—lattice relaxation of 13C nuclei in organic liquids

1971 • 17 citations

Linear electric field dependence of¹³C-H nuclear spin-spin couplings

1969 • 13 citations

Nuclear magnetic resonance spectroscopy. Carbon-13 spectra of n-alkyl nickel(II) aminotroponiminates

1970 • 11 citations

Signal-to-noise ratio in Fourier transform spectrometry

1972 • 11 citations

Bond-angle dependence of 13C NMR chemical shifts in some carbon sp3 systems

1971 • 9 citations

Paramagnetic Contribution to the 13C Shielding Constant in Benzene

1969 • 7 citations

Studies on the Proton Magnetic Resonance Spectra in Aromatic Systems. XIV. On the meta <SUP>1</SUP>H and <SUP>13</SUP>C Chemical Shift of Monosubstituted Benzene and Pyridine Series

1969 • 5 citations

Inversion of Carbon-13 NMR Signal in 13C–1H Double Resonance

1971 • 1 citations