1. Polypeptide Chain Initiation

RNA Codewords and Protein Synthesis

1964 • 1,400 citations

Use of Frog Eggs and Oocytes for the Study of Messenger RNA and its Translation in Living Cells

1971 • 774 citations

Polypeptide Chain Initiation: Nucleotide Sequences of the Three Ribosomal Binding Sites in Bacteriophage R17 RNA

1969 • 640 citations

Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein

1972 • 528 citations

Purification and properties of bacteriophage MS2 and of its ribonucleic acid

1963 • 411 citations

Initiation of mammalian protein synthesis: the importance of ribosome and initiation factor quality for the efficiency of in vitro systems

1973 • 388 citations

N-Formyl-methionyl-S-RNA

1964 • 349 citations

The role of N-formyl-methionyl-sRNA in protein biosynthesis

1966 • 335 citations

Nucleotide Sequence from the Coat Protein Cistron of R17 Bacteriophage RNA

1969 • 320 citations

Initiation of Eukaryotic Protein Synthesis: [Met-tRNAf.40S Ribosome] Initiation Complex Catalysed by Purified Initiation Factors in the Absence of mRNA

1973 • 306 citations

N-formylmethionyl-sRNA as the initiator of protein synthesis.

1966 • 296 citations

Partial resistance of nascent polypeptide chains to proteolytic digestion due to ribosomal shielding

1967 • 290 citations

Initiation of Haemoglobin Synthesis by Methionyl-tRNA

1970 • 278 citations

Cytoplasmic Methionine Transfer RNAs from Eukaryotes

1970 • 273 citations

Catalysis of peptide bond formation by 50 s ribosomal subunits from Escherichia coli

1967 • 272 citations

Role of Methionine in the Initiation of Haemoglobin Synthesis

1970 • 258 citations

Some physical properties of bacteriophage R17 and its ribonucleic acid

1964 • 255 citations

Mammalian Cell‐Free Protein Synthesis Directed by Viral Ribonucleic Acid

1970 • 251 citations

Secondary structure of bacteriophage f2 ribonucleic acid and the initiation of in vitro protein biosynthesis

1970 • 235 citations

The mechanism of sodium fluoride and cycloheximide inhibition of hemoglobin biosynthesis in the cell-free reticulocyte system

1966 • 202 citations

Mitochondrial and Cytoplasmic Polysomes from Neurospora crassa

1967 • 202 citations

N-formylmethionyl transfer RNA in mitochondria from yeast and rat liver

1968 • 200 citations

The NH2-terminal residues of the proteins from cell-free extracts of E. coli

1963 • 199 citations

Factors for the Initiation of Haemoglobin Synthesis by Rabbit Reticulocyte Ribosomes

1970 • 190 citations

Cell-free Hemoglobin Synthesis

1970 • 176 citations

N-Formyl-Methionyl-sRibonucleic Acid and Chain Initiation in Protein Biosynthesis: Polypeptidyl-sribonucleic acid and amino-acyl-sribonucleic Acid Binding Sites on Ribosomes

1966 • 174 citations

Nucleotide Sequence from the Polypeptide Chain Termination Region of the Coat Protein Cistron in Bacteriophage R17 RNA

1970 • 171 citations

In vitro protein synthesis: chain initiation.

1966 • 166 citations

The Ancestry of Birds

1973 • 166 citations

Interaction of ribosomes and synthetic polyribonucleotides

1963 • 165 citations

Studies on polynucleotides

1967 • 165 citations

Studies on Polynucleotides

1969 • 161 citations

Initiator Codons in Eukaryotes

1970 • 157 citations

Sequence of a Ribosome Binding Site in Bacteriophage Qβ-RNA

1969 • 157 citations

Nucleotide Sequence at the Binding Site for Coat Protein on RNA of Bacteriophage R17

1972 • 157 citations

Initiation of polyphenylalanine synthesis by N-acetylphenylalanyl-SRNA.

1967 • 155 citations

Purification and Properties of Initiation Factor F3

1970 • 150 citations

Translation of the genetic message: factors involved in the initiation of protein synthesis.

1966 • 147 citations

Sequence of the First 175 Nucleotides from the 5′ Terminus of Qβ RNA synthesized in vitro

1969 • 146 citations

Ribosome-catalyzed peptidyl transfer: substrate specificity at the P-site.

1968 • 146 citations

PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30 S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS

1967 • 144 citations

Role of a protein factor in the functional binding of ribosomes to natural messenger RNA

1968 • 131 citations

Protein Initiation in Eukaryotes: Formation and Function of a Ternary Complex Composed of a Partially Purified Ribosomal Factor, Methionyl Transfer RNA _f , and Guanosine Triphosphate

1973 • 127 citations

Specificity in Bacterial Protein Synthesis : Role of Initiation Factors and Ribosomal Subunits

1970 • 123 citations

Initiation of E. coli proteins.

1966 • 118 citations

Significance of the free 70 s ribosomes in Escherichia coli extracts

1968 • 117 citations

Inhibitors of Ribosome Functions

1971 • 115 citations

Recognition of eukaryotic initiator tRNA by an initiation factor and the transfer of the methionine moiety into peptide linkage

1972 • 115 citations

TRANSLATION OF THE GENETIC MESSAGE, II. EFFECT OF INITIATION FACTORS ON THE BINDING OF FORMYL-METHIONYL-TRNA TO RIBOSOMES

1967 • 108 citations

Peptide Chain Elongation: Discrimination against the Initiator Transfer RNA by Microbial Amino-acid Polymerization Factors

1968 • 107 citations

A GTP Requirement for Binding Initiator tRNA to Ribosomes

1967 • 107 citations

Control of Translation by T4 Phage: Altered Binding of Disfavoured Messengers

1970 • 107 citations

Factor Dependent Binding of Methionyl-tRNAs to Reticulocyte Ribosomes

1970 • 104 citations

Ribosomal Binding of Labelled Initiation Factor F3

1971 • 104 citations

Translation of Two Messenger RNAs from Lens in a Cell Free System from Krebs II Ascites Cells

1972 • 99 citations

Messenger Discriminating Species of Initiation Factor F3

1971 • 99 citations

Separation of mitochondrial and cytoplasmic peptide chain elongation factors from yeast

1970 • 98 citations

Species Specificity of Polypeptide Chain Initiation

1969 • 98 citations

Formylmethionyl-tRNA Dependence of Amino Acid Incorporation in Extracts of Trimethoprim-Treated Escherichia coli

1966 • 97 citations

A Supernatant Factor Involved in Initiation Complex Formation with Eukaryotic Ribosomes

1971 • 95 citations

Ribosomal RNA and ribosomes from mitochondria of Neurospora crassa.

1967 • 93 citations

N-Formyl-Methionyl-sRibonucleic Acid and Chain Initiation in Protein Biosynthesis: Polypeptide Synthesis Directed by a Bacteriophage Ribonucleic Acid in a Cell-Free System

1966 • 91 citations

Involvement of N-formylmethionine in initiation of protein synthesis in cell-free extracts of Euglena gracilis

1967 • 88 citations

Cistron Specific Translation Control Protein in Escherichia coli

1972 • 88 citations

Characterization of Two Species of Methionine Transfer Ribonucleic Acid from Bakers' Yeast

1968 • 87 citations

Gene Order in the Bacteriophage R17 RNA : 5′–;A Protein–Coat Protein–Synthetase–3′

1970 • 86 citations

SELECTIVE TRANSLATION OF T4 TEMPLATE RNA BY RIBOSOMES FROM T4-INFECTED Escherichia coli

1969 • 86 citations

A factor required for ribosome dissociation in Escherichia coli.

1968 • 84 citations

Purification and Properties of Initiation Factor f-1

1969 • 79 citations

Interaction between Guanosine Derivatives and Factors involved in the Initiation of Protein Synthesis

1970 • 78 citations

The role of guanosine 5'-triphosphate in the initiation of peptide synthesis. 3. Binding of formylmethionyl-tRNA to ribosomes.

1967 • 77 citations

[27] Isolation and properties of protein factors involved in polypeptide chain initiation in Escherichia coli

1971 • 77 citations

Recycling of Initiation Factors IF‐1, IF‐2 and IF‐3

1973 • 76 citations

Fractionation of translation initiation factor B (F3) into cistron‐specific species

1970 • 76 citations

Partial purification and characterization of an initiation factor from rat liver which promotes the binding of phenylalanyl-tRNA to 40-S ribosomal subunits

1972 • 73 citations

Host Subunit of Qβ Replicase is Translation Control Factor i

1972 • 72 citations

The Function of 80 S Ribosomal Subunits and Effects of Some Antibiotics

1969 • 72 citations

Role of initiation factor B (F3) in the preferential translation of T4 late messenger RNA in T4 infected E. Coli

1970 • 68 citations

Isolation of Protein Synthesis Initiation Factors from Rabbit Liver

1973 • 67 citations

Studies on the Role of Guanosine Triphosphate in Polypeptide Chain Initiation in Escherichia coli

1972 • 67 citations

Peptide Chain Termination with Mammalian Release Factor

1970 • 67 citations

Regulation of protein synthesis directed by coliphage MS2 RNA

1969 • 66 citations

PHYSICAL AND CHEMICAL PROPERTIES OF RNA FROM THE BACTERIAL VIRUS R17

1963 • 65 citations

Ribosomal proteins

1967 • 65 citations

Synthesis of Myosin on Heterologous Ribosomes

1969 • 65 citations

Translational control of bacteriophage MS2 RNA cistrons by MS2 coat protein: Polyacrylamide gel electrophoretic analysis of proteins synthesized in vitro

1968 • 63 citations

The Interaction of Radioactive Initiation Factor IF-2 with Ribosomes during Initiation of Protein Synthesis

1973 • 63 citations

Binding of Formylmethionyl-tRNA to 30S Ribosomal Sub-units

1968 • 62 citations

The Ribosome Dissociation Factor and the Ribosome-Polysome Cycle

1969 • 62 citations

A Complex Between Initiation Factor IF2, Guanosine Triphosphate, and fMet-tRNA _f : An Intermediate in Initiation Complex Formation

1971 • 60 citations

Evidence for a soluble protein factor specific for the interaction between aminoacylated transfer RNA's and the 40 s subunit of mammalian ribosomes

1972 • 57 citations

Polypeptide chain initiation in eukaryotes

1973 • 55 citations

Isolation of Protein Initiation Factors from 30S Ribosomal Subunits

1969 • 55 citations

GTP-stimulated Binding of Initiator-tRNA to Ribosomes directed by f2 Bacteriophage RNA

1967 • 54 citations

Initiation of protein synthesis. 3. Factor-GTP-codon-dependent binding of F-met-tRNA to ribosomes.

1967 • 53 citations

Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis.

1967 • 53 citations

Presence of N‐formyl‐methionyl‐transfer RNA in bean chloroplasts

1969 • 53 citations

Specificity of mitochondrial and cytoplasmic ribosomes from Neurospora crassa in poly‐U dependent cell free systems

1969 • 52 citations

Entry site of formylmethionyl‐tRNA

1972 • 52 citations

A Factor from Escherichia coli Concerned with the Stimulation of Cell-Free Polypeptide Synthesis by Exogenous Ribonucleic Acid. II. Characteristics of the Reaction Promoted by the Stimulation Factor^*

1966 • 52 citations

Formylmethionine Codon AUG as an Initiator of Polypeptide Synthesis

1966 • 52 citations

Control of translation of MS2 RNA cistrons by MS2 coat protein.

1967 • 52 citations

Mitochondrial and cytoplasmic ribosomes from Neurospora crassa: Characterization of their subunits

1969 • 51 citations

Bacteriophage Coat Protein as Repressor

1968 • 51 citations

A New Method for the Purification of Initiation Factor F2 in High Yield, and an Estimation of Stoichiometry in the Binding Reaction

1970 • 51 citations

Translation of the genetic message. VI. The role of ribosomal subunits in binding of formylmethionyl-tRNA and its reaction with puromycin.

1967 • 50 citations

Amino Acid Incorporation and Aminoacyl Transfer in an Insect Pupal System

1968 • 50 citations

Untranslated Nucleotide Sequences in R17 Bacteriophage RNA

1970 • 50 citations

Thermal melting of bacteriophage f2 RNA and initiation of synthesis of the maturation protein

1971 • 49 citations

Chain Initiation Factor 2

1973 • 48 citations

Further Studies with Labelled Polypeptide‐Chain‐Initiation Factor 3 (IF‐3)

1973 • 48 citations

Protein Chain Initiation in Wheat Embryo

1972 • 47 citations

THE INITIATION OF VIRAL PROTEIN SYNTHESIS IN E. COLI EXTRACTS

1966 • 47 citations

Purification of initiator C from Escherichia coli: a protein which binds messenger RNA and initiator tRNA to the 30 s ribosome

1969 • 45 citations

Molecular Bioenergetics and Macromolecular Biochemistry

1972 • 45 citations

Studies on the binding of turnip yellow mosaic virus RNA to Escherichia coli ribosomes

1967 • 42 citations

POLYPEPTIDE CHAIN INITIATION IN E. coli : STUDIES ON THE FUNCTION OF INITIATION FACTOR F ₁

1969 • 42 citations

Translation of the genetic message

1968 • 42 citations

Inhibition by thiostrepton of the IF‐2‐dependent ribosomal GTPase

1972 • 40 citations

Translation of the genetic message. V. Effect of Mg++ and formylation of methionine in protein synthesis.

1967 • 40 citations

Hybrid Ribosome Formation from Escherichia coli and Chloroplast Ribosome Subunits

1971 • 39 citations

Phosphorylation of Initiation Factor IF-2 from Escherichia coli with Skeletal Muscle Kinase

1972 • 39 citations

Isolation and Properties of Crystalline Initiation Factor F₁ from Escherichia coli Ribosomes

1971 • 39 citations

Separation of Reticulocyte Initiation Factor M ₂ Activity into Two Components

1972 • 37 citations

A novel ribosomal RNA in hamster cell mitochondria

1967 • 36 citations

Isolation and Properties of Polypeptide Chain Initiation Factor FII from Escherichia coli: Evidence for a Dual Function

1971 • 36 citations

Protein Chain Initiation by Methionyl-tRNA in Wheat Embryo

1970 • 35 citations

POLYPEPTIDE CHAIN INITIATION IN E. coli : ISOLATION OF HOMOGENEOUS INITIATION FACTOR F ₂ AND ITS RELATION TO RIBOSOMAL PROTEINS

1969 • 35 citations

Specific Dissociation of Ribosomes from Saccharomyces cerevisiae by a Protein Factor

1970 • 35 citations

Sedimentation properties of mitochondrial and cytoplasmic ribosomal RNA's from Neurospora.

1967 • 34 citations

Requirement for GTP in the Initiation Process on Reticulocyte Ribosomes and Ribosomal Subunits

1971 • 33 citations

Messenger Selection by Bacterial Ribosomes

1973 • 33 citations

NSF's Bid for Relevance

1972 • 32 citations

A Ribosome Dissociation Factor from Rabbit Reticulocytes

1972 • 32 citations

Puromycin-Peptide Bond Formation with Reticulocyte Initiation Factors M ₁ and M ₂

1971 • 31 citations

The Selective Inhibition of Protein Initiation by T4 Phage-Induced Factors

1970 • 31 citations

Polypeptide Chain Initiation in Eukaryotes: Functional Identity of Supernatant Factor from Various Sources

1972 • 30 citations

An initiation factor causing dissociation of E. coli ribosomes

1970 • 30 citations

POLYPEPTIDE CHAIN INITIATION IN E. coli : SULFHYDRYL GROUPS AND THE FUNCTION OF INITIATION FACTOR F ₂

1969 • 30 citations

Effect of Thiostrepton on Recycling of Escherichia coli Initiation Factor 2

1973 • 29 citations

Association of polypeptide initiation factors with 30 S ribosomal subunits

1969 • 29 citations

Initiation Factor 2-Dependent Ribosomal Binding of N -Formylmethionyl-Transfer RNA Without Added Guanosine Triphosphate

1972 • 24 citations

Presence of two sets of ribosome-specific transfer factors in the cell-free extracts from the non-photosynthetic alga Prototheca zopfii

1970 • 24 citations

Biosynthesis of Phage-specific Initiation Dipeptides

1971 • 24 citations

Recycling of the initiation factor IF‐3 on 30 S ribosomal subunits of E. coli

1973 • 23 citations

Protein Synthesis in Rabbit Reticulocytes

1971 • 23 citations

Characterization of the Initial Peptide of Qβ RNA Polymerase and Control of Its Synthesis

1971 • 22 citations

No Cancer Remission for NIH

1971 • 21 citations

Translational control of bacteriophage MS2 RNA cistrons by MS2 coat protein: Affinity and specificity of the interaction of MS2 coat protein with MS2 RNA

1970 • 20 citations

Studies on polypeptide chain initiation factors F₁ and F₂

1971 • 20 citations

Peptide Synthesis by Prokaryotic-Eukaryotic Hybrid Ribosomes

1972 • 19 citations

Effect of GTP on the dissociation of 70 S ribosomes

1969 • 18 citations

Formation of a Mammalian Initiation Complex with Reovirus Messenger RNA, Methionyl-tRNA _F , and Ribosomal Subunits

1972 • 16 citations

Polypeptide Chain Initiation and Stepwise Elongation with Artemia Ribosomes and Factors

1972 • 14 citations

A soluble factor from yeast which promotes a GTP‐dependent binding ofN‐acetylphenylalanyl‐tRNA to the ribosomes

1972 • 13 citations

Coat Protein Repression of Bacteriophage M12 RNA Directed Polysome Formation

1970 • 13 citations

Selective utilization of nonformylatable species of methionyl-tRNA's from Escherichia coli and yeast in a reticulocyte cell-free system

1970 • 9 citations

100 Years Ago

1971 • 8 citations

Factor and GTP requirements in a eukaryotic protein initiation system with reovirus messenger RNA, Met‐tRNA_F, and ribosomal subunits

1972 • 6 citations