Evolutionary and Population Perspectives of the Human HLA Complex

Statistical Power Analysis for the Behavioral Sciences

1989 • 83,906 citations

Statistical power analysis for the behavioral sciences

1990 • 65,781 citations

Women, Fire, and Dangerous Things: What Categories Reveal about the Mind

1988 • 7,419 citations

THE GENETIC BASIS OF EVOLUTIONARY CHANGE

1975 • 3,588 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

The sampling theory of selectively neutral alleles

1972 • 2,158 citations

Pattern of nucleotide substitution at major histocompatibility complex class I loci reveals overdominant selection

1988 • 1,968 citations

THE INTERACTION OF SELECTION AND LINKAGE. I. GENERAL CONSIDERATIONS; HETEROTIC MODELS

1964 • 1,829 citations

Common West African HLA antigens are associated with protection from severe malaria

1991 • 1,570 citations

The Genetic Basis of Evolutionary Change.

1975 • 1,439 citations

The effect of change in population size on DNA polymorphism.

1989 • 1,373 citations

Natural history of the major histo-compatibility complex

1987 • 1,274 citations

Gametic Disequilibrium Measures: Proceed With Caution

1987 • 930 citations

HLA and Disease Associations

1985 • 893 citations

The Neolithic Transition and the Genetics of Populations in Europe

1984 • 892 citations

The Neolithic Transition and the Genetics of Populations in Europe.

1986 • 792 citations

On measures of gametic disequilibrium.

1988 • 727 citations

THE HOMOZYGOSITY TEST OF NEUTRALITY

1978 • 689 citations

Allelic genealogy under overdominant and frequency-dependent selection and polymorphism of major histocompatibility complex loci.

1990 • 688 citations

Synthetic Maps of Human Gene Frequencies in Europeans

1978 • 659 citations

Mating patterns in seminatural populations of mice influenced by MHC genotype

1991 • 652 citations

Theoretical Aspects of Population Genetics.

1972 • 551 citations

The natural history of the major histocompatibility complex

1987 • 468 citations

Polymorphism, recombination, and linkage disequilibrium within the HLA class II region.

1992 • 416 citations

HLA-A and B polymorphisms predate the divergence of humans and chimpanzees

1988 • 341 citations

EVIDENCE FOR BALANCING SELECTION AT HLA

1983 • 329 citations

Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity

1990 • 325 citations

Genetic evidence for the spread of agriculture in Europe by demic diffusion

1991 • 303 citations

Murine Major Histocompatibility Complex Class-I Mutants: Molecular Analysis and Structure-Function Implications

1986 • 286 citations

MHC polymorphism pre-dating speciation

1988 • 273 citations

Hemolin: an Insect-Immune Protein Belonging to the Immunoglobulin Superfamily

1990 • 247 citations

Nucleotide sequences of chimpanzee MHC class I alleles: evidence for trans-species mode of evolution.

1988 • 240 citations

Small-Sample Comparisons of Exact Levels for Chi-Squared Goodness-of-Fit Statistics

1978 • 235 citations

Structural basis of the polymorphism of human complement components C4A and C4B: gene size, reactivity and antigenicity.

1986 • 220 citations

Histocompatibility Testing

2000 • 219 citations

Linkage disequilibrium due to random genetic drift

1969 • 198 citations

Single-sperm typing: determination of genetic distance between the G gamma-globin and parathyroid hormone loci by using the polymerase chain reaction and allele-specific oligomers.

1989 • 195 citations

Rapid HLA-DPB typing using enzymatically amplified DNA and nonradioactive sequence-specific oligonucleotide probes

1990 • 189 citations

DNA variation of the mammalian major histocompatibility complex reflects genomic diversity and population history.

1990 • 184 citations

Structure, Organization, and Regulation of the Complement Genes

1988 • 178 citations

Immunobiology of HLA

1989 • 175 citations

Women, Fire, and Dangerous Things: What Categories Reveal about the Mind

1988 • 168 citations

Rapid typing of DNA sequence polymorphism at the HLA-DRB1 locus using the polymerase chain reaction and nonradioactive oligonucleotide probes

1991 • 167 citations

Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B.

1989 • 164 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification III. Typing for 24 alleles of HLA-DP

1991 • 155 citations

Theoretical Aspects of Population Genetics.

1972 • 150 citations

Ancient roots for polymorphism at the HLA-DQ alpha locus in primates.

1989 • 149 citations

The colonization of the pacific: A genetic trail

1990 • 146 citations

Megabase-Scale Mapping of the HLA Gene Complex by Pulsed Field Gel Electrophoresis

1987 • 126 citations

Allelic polymorphism in transcriptional regulatory regions of HLA-DQB genes.

1991 • 116 citations

Linkage disequilibrium among multiple neutral alleles produced by mutation in finite population

1975 • 115 citations

Evolution at the Molecular Level

1992 • 113 citations

Chromosomal organization of the human major histocompatibility complex class I gene family.

1989 • 112 citations

COMPARISON OF RFLP-DR BETA AND SEROLOGICAL HLA-DR TYPING IN 1500 INDIVIDUALS

1990 • 112 citations

Molecular Evolution of the Major Histocompatibility Complex

1991 • 109 citations

Heterozygosity at individual amino acid sites: extremely high levels for HLA-A and -B genes.

1991 • 102 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. I. Typing for subsets of HLA-DR4

1990 • 96 citations

The Colonization of the Pacific: a genetic trail

1990 • 94 citations

Contrasting evolutionary histories among tightly linked HLA loci.

1986 • 83 citations

Multiple genetic mechanisms have contributed to the generation of the HLA-A2/A28 family of class I MHC molecules.

1987 • 81 citations

Recombinational hotspot specific to female meiosis in the mouse major histocompatibility complex

1990 • 78 citations

The Major Histocompatibility Complex and the Quest for Origins

1990 • 73 citations

Nomenclature for factors of the HLA system, 1991. The WHO Nomenclature Committee for factors of the HLA system.

1992 • 72 citations

Evidence for heterosis in the HLA system.

1981 • 70 citations

The major histocompatibility complex in the chicken

1989 • 68 citations

Immunogenetics of the major histocompatibility complex

1991 • 63 citations

Molecular Basis of Human Leukocyte Antigen Class II

1990 • 58 citations

Physical map of the human HLA region

1988 • 53 citations

Gene conversion in the evolution of the human and chimpanzee MHC class I loci

1991 • 50 citations

Investigations in farm animals of associations between the MHC system and disease resistance and fertility

1989 • 49 citations

FREQUENCY DISTRIBUTION OF ESTERASE-5 ALLELES IN TWO POPULATIONS OF DROSOPHILA PSEUDOOBSCURA

1983 • 48 citations

Influence of the Major Histocompatibility Complex on Tumor Regression and Immunity in Chickens

1987 • 48 citations

An analysis of variation in the long-range genomic organization of the human major histocompatibility complex class II region by pulsed-field gel electrophoresis

1989 • 47 citations

Molecular Genetics and Polymorphism of Class I HLA Antigens

1987 • 46 citations

Comparison of HLA class I gene sequences. Derivation of locus-specific oligonucleotide probes specific for HLA-A, HLA-B, and HLA-C genes.

1985 • 43 citations

DNA typing for class II HLA antigens with allele-specific or group-specific amplification

1991 • 43 citations

Comparison of the structure of HLA-Bw47 to HLA-B13 and its relationship to 21-hydroxylase deficiency

1988 • 38 citations

Disequilibrium Pattern Analysis. II. Application to Danish HLA A and B Locus Data

1987 • 37 citations

Three-locus systems impose additional constraints on pairwise disequilibria.

1991 • 36 citations

Microconversion between murine H-2 genes integrated into yeast

1990 • 33 citations

Analysis of Multilocus Pedigree Data by Computer

1984 • 33 citations

Transgenic Mice and Mutants in MHC Research

1990 • 33 citations

HLA-sharing, recurrent spontaneous abortion, and the genetic hypothesis.

1988 • 32 citations

A comprehensive search for segregation distortion in HLA

1987 • 30 citations

Selection, hitchhiking and disequilibrium analysis at three linked loci with application to HLA data.

1991 • 30 citations

Disequilibrium Pattern Analysis. I. Theory

1987 • 30 citations

Human population genetics

1985 • 29 citations

The same MHC recombinational hot spots are active in crossing-over between wild/wild and wild/inbred mouse chromosomes

1988 • 25 citations

Immunogenetic studies of two recently contacted populations from Papua New Guinea.

1989 • 25 citations

Class II Mhc Genes in Rodent Evolution

1990 • 22 citations

Multiplicative Models for Dyad Formation

1976 • 19 citations

Genetic organization of the chicken MHC

1990 • 18 citations

Gene conversion in the evolution of both the H-2 and Qa class I genes of the murine major histocompatibility complex.

1990 • 18 citations

The HLA genetic constitution of the Bushmen (San)

1990 • 14 citations

Paradoxes in Immunology

2019 • 12 citations

HLA in Medicine

1997 • 11 citations

Selection by Typhoid and Yellow Fever Epidemics Witnessed by the HLA-DR Locus

1989 • 10 citations

Spontaneous Frequency of H-2 Mutations

1990 • 10 citations

Introduction

1987 • 8 citations

[The immunoglobulin gene superfamily].

1988 • 5 citations

Evolution of the MHC: Lessons from the nonmammalian vertebrates

1990 • 3 citations

Evidence for a Hot Spot for Generalized Gene Conversion in the Second Exon of MHC Genes

1989 • 2 citations

Interpreting MHC Disequilibrium

1991 • 1 citations