Posttranslational processing of a human myeloid lysosomal protein, myeloperoxidase

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

High resolution two-dimensional electrophoresis of basic as well as acidic proteins

1977 • 3,556 citations

Fluorographic detection of radioactivity in polyacrylamide gols with the water-soluble fluor, sodium salicylate

1979 • 1,976 citations

LYSOSOMAL ENZYMES AND THEIR RECEPTORS

1986 • 915 citations

Perturbation of vesicular traffic with the carboxylic ionophore monensin

1983 • 890 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.

1980 • 809 citations

endo-beta-N-acetylglucosaminidase F: endoglycosidase from Flavobacterium meningosepticum that cleaves both high-mannose and complex glycoproteins.

1982 • 689 citations

IODINATION OF BACTERIA: A BACTERICIDAL MECHANISM

1967 • 621 citations

Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.

1977 • 580 citations

Swainsonine inhibits the biosynthesis of complex glycoproteins by inhibition of Golgi mannosidase II.

1982 • 463 citations

A hypothesis for I-cell disease: Defective hydrolases that do not enter lysosomes

1972 • 446 citations

The response of fluorescent amines to pH gradients across liposome membranes

1972 • 261 citations

Castanospermine inhibits the processing of the oligosaccharide portion of the influenza viral hemagglutinin

1983 • 251 citations

Myeloperoxidase: its structure and expression during myeloid differentiation

1985 • 184 citations

Purification and characterization of alpha-D-mannosidase from rat liver golgi membranes.

1977 • 178 citations

Is there a mechanism for introducing acid hydrolases into liver lysosomes that is independent of mannose 6-phosphate recognition? evidence from I-cell disease

1982 • 169 citations

Characterization of cDNA clones for human myeloperoxidase: Predicted amino acid sequence and evidence for multiple mRNA species

1987 • 169 citations

Evidence for an alpha-mannosidase in endoplasmic reticulum of rat liver.

1983 • 164 citations

Deficiency of UDP-N-acetylglucosamine: Lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients

1982 • 147 citations

Molecular cloning and characterization of cDNA for human myeloperoxidase.

1987 • 142 citations

Biochemical and Immunologic Analysis of Hereditary Myeloperoxidase Deficiency

1983 • 115 citations

Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins.

1983 • 110 citations

Myeloperoxidase biosynthesis by a human promyelocytic leukemia cell line: insight into myeloperoxidase deficiency

1986 • 98 citations

Cathepsin D and beta-hexosaminidase synthesized in the presence of 1-deoxynojirimycin accumulate in the endoplasmic reticulum.

1984 • 84 citations

Inhibition of formation of complex oligosaccharides by the glucosidase inhibitor bromoconduritol.

1982 • 84 citations

Co-translational excision of alpha-glucose and alpha-mannose in nascent vesicular stomatitis virus G protein.

1984 • 83 citations

Regulation of myeloperoxidase gene expression during differentiation of human myeloid leukemia HL-60 cells.

1984 • 78 citations

Myeloperoxidase is synthesized as larger phosphorylated precursor.

1984 • 74 citations

Processing of a newly identified intermediate of human myeloperoxidase in isolated granules occurs at neutral pH.

1986 • 61 citations

Synthesis and transport of lysosomal acid phosphatase in normal and I-cell fibroblasts.

1985 • 60 citations

Inhibition of asparagine-linked glycosylation by incorporation of a threonine analog into nascent peptide chains.

1980 • 50 citations

Miscleavage at the presequence of rat preprolactin synthesized in pituitary cells incubated with a threonine analog

1981 • 48 citations

Effects of ammonia on processing and secretion of precursor and mature lysosomal enzyme from macrophages of normal and pale ear mice: evidence for two distinct pathways.

1985 • 48 citations

The processing and intracellular transport of myeloperoxidase. Modulation by lysosomotropic agents and monensin.

1986 • 43 citations

Separation and analysis of subcellular organelles in a human promyelocytic leukemia cell line, HL-60: application to the study of myeloid lysosomal enzyme synthesis and processing

1986 • 29 citations