Experimental and Clinical Aspects of Drug Toxicity

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

Estimation of the ED50 and Its Error by Means of Logarithmic-Probit Graph Paper.

1944 • 1,110 citations

A Method for the Fluorimetric Determination of Adrenaline and Noradrenaline in Tissues.¹

1958 • 1,029 citations

Handbuch der allgemeinen pathologie

1973 • 816 citations

The action of sympathomimetic amines in animals treated with reserpine

1958 • 746 citations

Versuchsanordnung zu Untersuchungen an der Bronchiàlmuskulatur

1940 • 660 citations

Comparative assays of antiepileptic drugs in mice and rats.

1952 • 638 citations

Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs.

1960 • 511 citations

Therapeutic Abortions with a Folic Acid Antagonist, 4-Aminopteroylglutamic Acid (4-Amino P. G. A.) Administered by the Oral Route

1952 • 402 citations

Experimental Production of Congenital Malformations in Mammals by Metabolic Procedure

1959 • 383 citations

Species, strain and sex differences in metabolism of hexobarbitone, amidopyrine, antipyrine and aniline

1958 • 372 citations

The dissociation of bilirubin from albumin and its clinical implications

1959 • 293 citations

STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS. II

1936 • 292 citations

Drug Metabolism in the Newborn Rabbit

1959 • 281 citations

Studies on sympathomimetic amines. II. The biotransformation and physiological disposition of d-amphetamine, d-p-hydroxyamphetamine and d-methamphetamine.

1954 • 258 citations

MASCULINIZATION OF FEMALE FETUS DUE TO USE OF ORALLY GIVEN PROGESTINS

1960 • 240 citations

The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material.

1953 • 240 citations

RHEUMATIC AND FEBRILE SYNDROME DURING PROLONGED HYDRALAZINE TREATMENT

1954 • 226 citations

Inability of newborn mice and guinea pigs to metabolize drugs

1959 • 223 citations

Hyperglycemia and Glycosuria Due to Thiazide Derivatives Administered in Diabetes Mellitus

1960 • 208 citations

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1962 • 202 citations

Experimental production of congenital malformations in rats by salicylate poisoning.

1959 • 198 citations

Pharmacological Studies with Tofrānil

1959 • 188 citations

Effect of Isoniazid on Vitamin B6 Metabolism; Its Possible Significance in Producing Isoniazid Neuritis.

1954 • 186 citations

Resistance Strain Gauge Arches for Direct Measurement of Heart Contractile Force in Animals.

1953 • 181 citations

The enzymatic N-demethylation of narcotic drugs.

1956 • 171 citations

THE INHERITANCE OF SUSCEPTIBILITY TO THE TERATOGENIC ACTION OF CORTISONE IN MICE

1954 • 168 citations

The Treatment of Dermatomycoses with Orally Administered Griseofulvin

1959 • 166 citations

STUDIES ON THE MECHANISM OF THE FORMATION OF THE PENICILLIN ANTIGEN

1960 • 166 citations

EFFECTS OF ISONIAZID ON PYRIDOXINE METABOLISM

1954 • 164 citations

Acute Pancreatic Lesions in Patients Treated with ACTH and Adrenal Corticoids

1957 • 163 citations

Plasma cholesterol lowering action of bile acid binding polymers in experimental animals

1960 • 159 citations

Mechanism of the potentiating action of beta-diethylaminoethyl diphenylpropylacetate.

1954 • 159 citations

Photoallergy and Primary Photosensitivity to Sulfanilamide11I wish to express my thanks to Dr. R. P. Potter for his assistance in the preparation of this paper.

1939 • 155 citations

The Methemoglobin Reduction Test for Primaquine-Type Sensitivity of Erythrocytes

1962 • 153 citations

PARA-AMINOBENZENESULFONAMIDE

1937 • 151 citations

Jaundice during methyl testosterone therapy

1950 • 150 citations

An experimental malabsorption syndrome induced by neomycin

1960 • 145 citations

Congenital Malformations in Offspring of Mice Treated with Caffcine.

1960 • 141 citations

Psychotic Reactions Induced by Corticotropin (ACTH) and Cortisone

1953 • 137 citations

Leukoagglutinins

1954 • 136 citations

Some Cytological Effects of Griseofulvin

1958 • 133 citations

XLIX The Ototoxicity of Kanamycin

1959 • 129 citations

Experimental studies on congenital malformations

1959 • 124 citations

PSYCHOSOMATIC MEDICINE

1950 • 123 citations

Suppression of spermatogenesis and chronic toxicity in men by a new series of bis(dichloroacetyl) diamines

1961 • 122 citations

DRUG-INDUCED HEPATIC INJURY

1959 • 122 citations

On the chemical production of developmental abnormalities and of phenocopies in chicken embryos

1954 • 121 citations

COMPARATIVE ANTICONVULSIVE ACTION OF 3,5,5-TRIMETHYLOXAZOLIDINE-2,4-DIONE (TRIDIONE), DILANTIN AND PHENOBARBITAL

1944 • 120 citations

Effects of environmental temperature on the acute toxicity of a number of compounds in rats

1959 • 118 citations

The action of some amines related to adrenaline. Cyclohexylalkylamines

1940 • 118 citations

Leukaemia Following Radioiodine Treatment of Thyrotoxicosis

1960 • 118 citations

Effect of Chlorpromazine on the Behaviour of Chronically Overactive Psychotic Patients

1954 • 117 citations

The metabolism of drugs by liver microsomes from alloxan-diabetic rats.

1961 • 116 citations

Principles Governing the Genesis of Congenital Malformations Induced in Mice by Hypoxia

1957 • 114 citations

CORTISONE-INDUCED CONGENITAL CLEFT PALATE IN RABBITS¹

1954 • 112 citations

The metabolic fate of thalidomide

1962 • 109 citations

STUDIES ON THE SENSITIZATION OF ANIMALS WITH SIMPLE CHEMICAL COMPOUNDS

1937 • 107 citations

On the metabolic fate of isoniazid.

1953 • 104 citations

The role of body fat in limiting the duration of action of thiopental.

1952 • 101 citations

Phenacetin Takers Dead with Renal Failure

1961 • 99 citations

Hemolytic Effect of Therapeutic Drugs

1962 • 99 citations

Studies on the mechanism of a drug-induced hemolytic anemia.

1956 • 98 citations

HEMATOGENOUS PYELONEPHRITIS IN RATS. I. ITS PATHOGENESIS WHEN PRODUCED BY A SIMPLE NEW METHOD 12

1955 • 95 citations

The metabolic hydroxylation of phenobarbital.

1956 • 94 citations

THE OCULAR COMPLICATIONS OF CHLOROQUINE THERAPY

1958 • 94 citations

The influence of excess body fat on the cardiotoxicity of isoproterenol in rats

1962 • 91 citations

MASCULINIZATION OF THE FEMALE INFANT ASSOCIATED WITH ESTROGENIC THERAPY ALONE DURING GESTATION: FOUR CASES*

1959 • 90 citations

THE EFFECT OF OBSTRUCTIVE JAUNDICE ON DRUG METABOLISM IN RABBITS

1961 • 86 citations

Potentiation of the behavioral effects of amphetamine by imipramine

1961 • 86 citations

Part VI. Difficulties in extrapolating data on metabolism of drugs from animal to man

1962 • 85 citations

MASCULINIZATION OF FEMALE FETUSES IN THE RAT BY PROGESTATIONAL COMPOUNDS

1960 • 83 citations

Allergy to chlorpromazine manifested by jaundice

1957 • 82 citations

Influence of Body Fat on Duration of Thiopental Anesthesia

1952 • 82 citations

Clinical and Physiologic Implications of the Steroid-Induced Peptic Ulcer

1960 • 82 citations

Uric Acid Retention Due to Hydrochlorothiazide

1959 • 80 citations

X The Ototoxicity of Kanamycin in Guinea Pigs

1961 • 79 citations

Photosensitivity Due to Chlorothiazide and Hydrochlorothiazide

1959 • 77 citations

On the mechanism of drug potentiation by iproniazid (2-isopropyl-1-isonicotinyl hydrazine).

1956 • 73 citations

Accelerated aminopyrine metabolism in human subjects pretreated with phenylbutazone

1962 • 73 citations

Pathogenetical Correlations between Periarteritis Nodosa, Renal Hypertension and Rheumatic Lesions.

1943 • 73 citations

Developmental Anomalies in Offspring of Pregnant Mice Treated with Nicotine

1958 • 72 citations

The effects of ionizing radiation, certain hormones, and radiomimetic drugs on the developing nervous system

1954 • 72 citations

Studies on the mechanism of amphetamine toxicity in aggregated mice.

1961 • 71 citations

Intrahepatic cholestasis following administration of chlorpropamide

1960 • 71 citations

Nephrotic syndrome occurring during tridione therapy

1948 • 71 citations

Studies in detoxication. 74. The metabolism of benzhydrol, benzophenone and p-hydroxybenzophenone

1958 • 69 citations

Pancreatic lesions and peripancreatic fat necrosis in cortisone-treated rabbits.

1956 • 67 citations

Ascorbic acid in aromatic hydroxylation. III. Effect of ascorbic acid on hydroxylation of acetanilide, aniline and antipyrine in vivo.

1954 • 66 citations

PATHOLOGICAL FINDINGS IN JAUNDICE ASSOCIATED WITH IPRONIAZID THERAPY

1958 • 65 citations

Increased blood pressure responses to dopamine and norepinephrine produced by monoamine oxidase inhibitors in man.

1960 • 64 citations

Relative hepatotoxicity of seven halogenated hydrocarbons.

1958 • 64 citations

I. Mitteilungen – Communications. Experimentelle Untersuchungen zur Pathogenese des Kontaktekzems

1956 • 64 citations

Contrasting effects of thyroxin on zoxazolamine and hexobarbital metabolism

1961 • 63 citations

The effects of carbon dioxide on the entry and accumulation of drugs in the central nervous system.

1961 • 62 citations

Fatal nephritis in chronic phenacetin poisoning

1960 • 61 citations

Acute Myocardial Infarction Secondary to Ergot Therapy

1960 • 61 citations

Correlations of activating and lethal effects of excitatory drugs in grouped and isolated mice.

1961 • 61 citations

Experimental hydralazine disease and its similarity to disseminated lupus erythematosus.

1956 • 60 citations

CIRCULATORY RESPONSES DURING ANESTHESIA OF PATIENTS ON RAUWOLFIA THERAPY

1956 • 57 citations

Zur Frage der Angriffsorte von Compound E (Cortison)

1953 • 57 citations

Detection and Prevention of Drug-Induced Blood Dyscrasias

1962 • 56 citations

Inhibition of drug metabolic pathways by the potentiating agent, 2, 4-dichloro-6-phenyl-phenoxyethyl diethylamine.

1955 • 56 citations

HYPERTENSION

1962 • 55 citations

Amphetamine toxicity in rats and mice subjected to stress.

1961 • 54 citations

EFFECT OF LARGE DOSES OF AUREOMYCIN, TERRAMYCIN, AND CHLORAMPHENICOL ON LIVERS OF MICE AND DOGS

1951 • 54 citations

Variation in Response of Various Mouse Strains to Hexobarbital (Evipal)

1955 • 54 citations

CORTISONE INDUCED MODIFICATIONS IN THE DEVELOPMENT OF THE CHICK EMBRYO¹

1960 • 54 citations

Drug reactions characterized by cholestasis associated with intrahepatic biliary tract obstruction

1957 • 52 citations

OCCURRENCE OF THYROID NODULES IN CHILDREN FOLLOWING THERAPY WITH RADIOIODINE FOR HYPERTHYROIDISM*

1959 • 52 citations

Hematologic Complications Arising during Ristocetin Therapy

1958 • 50 citations

Gastric Mucosal Erosion in the Rat Following Administration of the Serotonin Precursor, 5-Hydroxytryptophan

1957 • 50 citations

The Hemorrhagic Disorders: A Clinical and Therapeutic Approach

1963 • 49 citations

PERSISTENCE OF THE "HYDRALAZINE SYNDROME"

1960 • 49 citations

GRISEOFULVIN FOR THE SYSTEMIC TREATMENT OF DERMATOMYCOSES

1959 • 48 citations

Use of the Trypan Blue and Rabbit Eye Tests for Irritation

1950 • 48 citations

Treatment of hyperemesis gravidarum with cortisone

1953 • 47 citations

The Effect Of Breed, Age, And Sex On Myocardial Necrosis Produced By Isoproterenol In The Rat

1959 • 47 citations

Prevalence, Nature and Identification of Leukocyte Antibodies

1958 • 47 citations

The fate of papaverine in man and other mammals.

1958 • 46 citations

Rapid Diagnosis of Drug-Induced Thrombocytopenic Purpura

1962 • 44 citations

Some Effects of Antibiotics on Nutrition in Man

1958 • 44 citations

Drug-Related Blood Dyscrasias

1961 • 43 citations

Immunopancytopenia Associated with Incomplete Cold Hemagglutinins in a Case of Primary Atypical Pneumonia

1954 • 42 citations

Disturbance of embryonic development by maternal vitamin deficiencies

1954 • 42 citations

Hepatic tests in toxicity studies on rats

1961 • 41 citations

Observations on the Effect of Phenacetin and N‐acetyl‐p‐aminophenol on Rat Kidneys

1961 • 41 citations

USE OF PYRIDOXINE HYDROCHLORIDE TO PREVENT ISONIAZID TOXICITY

1958 • 41 citations

CORNEAL COMPLICATION OF CHLOROQUINE (ARALEN) PHOSPHATE THERAPY

1958 • 40 citations

OTOTOXICITY OF KANAMYCIN

1959 • 40 citations

Strain difference in response of mice to d-amphetamine.

1962 • 40 citations

Diseases of the Nervous System.

1957 • 40 citations

Phenylbutazone (Butazolidin)—Studies on the Stimulation of Gastric Secretion and the Formation of Peptic Ulcer in Man

1955 • 39 citations

Malabsorptive Effects of Neomycin in Commonly Used Doses

1961 • 39 citations

The calculation of biological assay results by graphic methods; the all-or-none type of response.

1945 • 39 citations

Liver Damage Concurrent with Iproniazid Administration

1958 • 39 citations

An experimental production of coronary thrombosis and myocardial failure

1936 • 39 citations

Chronic oral toxicities of four stearic acid emulsifiers

1959 • 38 citations

CORTISONE-INDUCED BONE RESORPTION IN THE RABBIT

1961 • 38 citations

The immunological basis of purpura due to drug hypersensitivity.

1962 • 38 citations

ALOPECIA AND OTHER TOXIC EFFECTS OF HEPARIN AND SYNTHETIC HEPARINOIDS

1954 • 37 citations

Hepatomegaly with Fatty Infiltration Secondary to Cortisone Therapy: Case Report

1952 • 37 citations

Toxicology of hydroxypyridinethione

1960 • 36 citations

Focal Hepatitis, Fever and Skin Rash Following Therapy with Sulfamethoxypyridazine, a Long-Acting Sulfonamide

1958 • 36 citations

Production of Impending Hepatic Coma by a Carbonic Anhydrase Inhibitor, Diamox.

1956 • 36 citations

THE TREATMENT OF PSORIASIS AND OTHER DERMATOSES WITH TRIAMCINOLONE (ARISTOCORT)

1958 • 36 citations

Influence of age on the sensitivity of the guinea pig and its myocardium to ouabain.

1953 • 36 citations

INTOXICATION FROM PRIMIDONE DUE TO ITS BIOTRANSFORMATION TO PHENOBARBITAL

1958 • 36 citations

The biotransformation of ethyl biscoumacetate (tromexan) in man, rabbit and dog.

1953 • 35 citations

Photosensitivity to Drugs

1961 • 35 citations

Species differences in the cardiac effects of a monoamine oxidase inhibitor.

1962 • 35 citations

Aggravation of Diabetes Mellitus During Treatment with Chlorothiazide

1961 • 34 citations

LIGHT SENSITIVITY DUE TO DEMETHYLCHLORTETRACYCLINE

1960 • 34 citations

Thalidomide Disaster Considered as an Experiment in Mammalian Teratology

1962 • 33 citations

Production of Impending Hepatic Coma by Chlorothiazide and Its Prevention by Antibiotics

1958 • 33 citations

Nodular panniculitis after massive prednisone therapy

1958 • 33 citations

The Immunological Basis of Purpura Due to Drug Hypersensitivity

1962 • 32 citations

Jaundice associated with the administration of iproniazid

1958 • 31 citations

NEPHROTIC SYNDROME OCCURRING DURING PARAMETHADIONE THERAPY

1953 • 30 citations

The Enhancement of the Toxicity of Sodium Fluoride in the Rat by High Dietary Fat

1955 • 30 citations

ACUTE ATTACKS OF GOUT PRECIPITATED BY CHLOROTHIAZIDE-INDUCED DIURESIS

1960 • 30 citations

Hydralazine Disease in the Guinea-pig as an Experimental Model for Lupus Erythematosus

1962 • 29 citations

Species Dependence of Chlorpromazine Metabolism.

1961 • 29 citations

FATAL JAUNDICE AFTER ADMINISTRATION OF BETA-PHENYLISOPROPYLHYDRAZINE

1959 • 29 citations

THROMBOCYTOPENIC PURPURA ASSOCIATED WITH HYDROCHLOROTHIAZIDE THERAPY

1960 • 29 citations

PHOTOSENSITIVITY DUE TO TETRACYCLINE DERIVATIVE

1960 • 29 citations

Withdrawal Convulsions in Dogs Following Chronic Meprobamate Intoxication

1958 • 28 citations

THE EFFECTS OF TOLBUTAMIDE AND CHLORPROPAMIDE ON PATIENTS EXHIBITING JAUNDICE AS A RESULT OF PREVIOUS CHLORPROPAMIDE THERAPY

1959 • 28 citations

Distribution and excretion of radioactivity in rats receiving N-methyl-C14-erythromycin.

1956 • 28 citations

ERYTHEMA MULTIFORME EXUDATIVUM ASSOCIATED WITH USE OF SULFAMETHOXYPYRIDAZINE

1960 • 27 citations

Abstinence syndrome in dogs after chronic barbiturate medication.

1954 • 27 citations

Effect of Cholinergic Drugs on Development of Chick Embryo.

1956 • 26 citations

Experimenteller Beitrag zur Frage von Nierenschäden bei Abusus von phenazetinhaltigen Schmerzmitteln

1955 • 26 citations

Antibiotic Toxicity in Newborn and Adult Rats

1961 • 26 citations

THE METABOLISM OF IPRONIAZID

1959 • 25 citations

The pathological effects of the administration of 2-methylamino-4-amino-6 : 7-diphenylpteridine to rats

1957 • 25 citations

SEPTIC ARTHRITIS AS A COMPLICATION OF ORALLY GIVEN STEROID THERAPY

1957 • 25 citations

HEPATIC DAMAGE DURING CHLORPROPAMIDE THERAPY

1959 • 25 citations

Augmentation of Toxicity of Monoamine Oxidase Inhibitor by Thyroid Feeding

1961 • 24 citations

PREDNISONE AND PREDNISOLONE THERAPY IN RHEUMATOID ARTHRITIS

1957 • 24 citations

CORTICOSTEROID THERAPY IN RHEUMATOID ARTHRITIS

1959 • 24 citations

DINITROPHENOL CATARACT: PRODUCTION IN AN EXPERIMENTAL ANIMAL

1944 • 24 citations

Infections Complicating Cortisone Therapy

1957 • 24 citations

Estrogen Therapy in Men with Myocardial Infarction

1960 • 22 citations

Der Einfluß von Thalidomid auf Wachstum und sexuelle Entwicklung von Hähnchen

1962 • 22 citations

The relationships among different in vivo properties of local anesthetics and toxicity to cell cultures in vitro

1959 • 21 citations

Placental transfer in normal and toxic gestation

1958 • 21 citations

Death Due to Hepatic Necrosis in a Patient Receiving Zoxazolamine

1961 • 21 citations

The Occurrence of Angiitis and of Other Generalized Diseases of Connective Tissues as a Consequence of the Administration of Drugs

1962 • 21 citations

Metabolic and histologic studies in patients with and without liver disease receiving chloramphenicol and oxytetracycline.

1954 • 20 citations

EXPERIMENTAL PATHOLOGY OF IPRONIAZID AND RELATED COMPOUNDS

1959 • 20 citations

Severe hypoglycemia after the ingestion of a sulfonylurea compound

1960 • 20 citations

Comparison of Some Metabolic and Morphologic Effects of Cortisone and Hydrocortisone Given by Continuous Injection to Rats

1952 • 20 citations

Phenylbutazone (Butazolidin)—Effect on Basal Gastric Secretion and the Production of Gastroduodenal Ulcerations in Dogs

1955 • 20 citations

Hematemesis and Melena Complicating Treatment with Rauwolfia Alkaloids

1957 • 20 citations

Studies on the metabolism of reserpine.

1956 • 20 citations

ACTIVATION OF PEPTIC ULCER BY NICOTINIC ACID

1960 • 19 citations

Plasma levels and excretion of codeine and metabolites in the dog and monkey.

1956 • 19 citations

Experiments with calculated therapeutic and toxic doses of digitalis

1944 • 19 citations

NEW ALLERGIC REACTION TO FURALTADONE

1960 • 18 citations

Primary Irritant and Allergic Eczematous Reactions

1957 • 18 citations

SUBDURAL HEMATOMA RELATED TO ANTICOAGULATION THERAPY

1958 • 18 citations

THERAPEUTIC USE OF VITAMIN B₁ IN DISEASES OTHER THAN BERIBERI

1962 • 17 citations

TRIMETHADIONE (TRIDIONE®) NEPHROSIS IN RATS

1960 • 17 citations

Experimental toxicologic studies on 8-methoxypsoralen in animals exposed to the long ultraviolet.

1961 • 17 citations

Toxicity Tests: A Guide For Clinicians

1962 • 17 citations

AMMONIA INTOXICATION IN A PATIENT WITH CIRRHOSIS TREATED WITH CHLOROTHIAZIDE

1958 • 16 citations

HYDRALAZINE POISONING

1960 • 16 citations

ACUTE LEUKEMIA AFTER RADIOACTIVE IODINE (I131) THERAPY FOR HYPERTHYROIDISM

1957 • 16 citations

A two-year study of the toxicity of chlortetracycline hydrochloride in rats

1961 • 15 citations

Strain and Sex Differences in Response of Inbred Mice to Adrenal Cortical Hormones

1952 • 15 citations

Demethylation of imipramine in male and female rats

1962 • 15 citations

ECCHYMOTIC SKIN LESIONS IN PATIENTS RECEIVING PREDNISONE

1957 • 15 citations

The Hemorrhagic Disorders: A Clinical and Therapeutic Approach

1955 • 15 citations

PROLONGED TREATMENT OF RHEUMATOID ARTHRITIS WITH PREDNISONE (METICORTEN)

1957 • 15 citations

Studies in the toxicology of griseofulvin

1960 • 15 citations

AGRANULOCYTOSIS DUE TO ADMINISTRATION OF SALICYLAZOSULFAPYRIDINE (AZULFIDINE)

1960 • 14 citations

Agranulocytosis Due to Mepazine (Phenothiazine)

1959 • 14 citations

LEUCOAGGLUTININS IN AGRANULOCYTOSIS

1955 • 14 citations

Allergy to Phenethicillin

1960 • 14 citations

Toxicologic and metabolic studies on 2,4-dimethoxy-6-sulfanilamido-1,3-diazine (Madribon)

1959 • 14 citations

Oxidation of phenethylamine derivatives by amine oxidase.

1946 • 14 citations

Effect of temperature on toxicity and distribution of pentobarbital and barbital in rats and dogs.

1962 • 14 citations

Experimental Sensitization of Guinea-Pigs to 1-hydrazinophthalazine; with a Discussion on the Use of Guinea-Pigs for the Forecast of Clinical Sensitizations*

1955 • 14 citations

THE RELATIONSHIP OF CERTAIN VITAMIN DEFICIENCIES TO THE TOXICITY OF IPRONIAZID

1959 • 14 citations

OBSERVATIONS OF CHLORPROMAZINE INDUCED JAUNDICE WITH CONTINUED USE OF THE DRUG

1957 • 14 citations

Early Potentiation of the Vasoconstrictor Action of Norepinephrine by Guanethidine.

1962 • 14 citations

Lichtbeeinflußte Arzneimittel-Nebenwirkungen an der Haut^*

1962 • 14 citations

Effect of chlorpromazine upon experimental hepatic injury.

1957 • 14 citations

IMMUNOTHROMBOCYTOPENIA INDUCED BY NOVOBIOCIN

1958 • 13 citations

The comparative pharmacology in man and the rat of the riboflavin analogu 6,7-dimethyl-9-(2-acetoxyethyl)-isoalloxazine, U-2112.

1958 • 13 citations

HYDRALAZINE SYNDROME—HYPERSENSITIVITY OR TOXICITY?

1957 • 13 citations

CLINICAL AND EXPERIMENTAL NEPHROPATHY RESULTING FROM USE OF NEOMYCIN SULFATE

1960 • 13 citations

Toxicologic studies on biperiden (Akineton) (1-bicycloheptenyl-1-phenyl-3-piperidinopropanol-1)*1, *2

1960 • 13 citations

Hazards to the Newborn Infant From Drugs Administered to the Mother

1961 • 13 citations

Glucose-6-Phosphate Dehydrogenase Activity in the Red Blood Cells of Monkeys

1962 • 13 citations

The effect of altered thyroid function on the actions and fate of d, 1-methadone.

1953 • 13 citations

CLINICAL OBSERVATIONS ON USE OF WARFARIN (COUMADIN) SODIUM, A NEW ANTICOAGULANT

1957 • 13 citations

ADVERSE REACTIONS TO SULFAMETHOXYPYRIDAZINE (KYNEX)

1959 • 12 citations

Studies on the Sex Difference in Toxicity of a Cholinergic Phosphorothioate.

1961 • 12 citations

BISHYDROXYCOUMARIN TOXICITY

1959 • 12 citations

Demethylchlortetracycline Phototoxicity

1961 • 12 citations

Screening of fluorine-containing compounds for acute toxicity

1960 • 12 citations

DIVISION OF BIOCHEMISTRY: CHEMOTHERAPEUTIC CONTROL OF SERUM LIPID LEVELS*

1962 • 12 citations

Iatrogenic Jaundice

1960 • 12 citations

Effect of Hyperthyroidism on Body Weight Gain and Feed Consumption in Male and Female Rats.

1961 • 12 citations

Toxicological Studies

1961 • 11 citations

IMMUNOTHROMBOCYTOPENIA INDUCED BY NOVOBIOCIN

1958 • 11 citations

ON ACTION OF NAPA (N‐ACETYL‐P‐AMINOPHENOL) ON THE INDUCTION OF INTERSTITIAL NEPHRITIS IN RATS

1962 • 11 citations

Toxicology of acetoxycycloheximide as a function of sex and body weight.

1962 • 11 citations

Potentiating Effects of Reserpine on Thyrotoxicity in the Rat.

1958 • 10 citations

Oral Moniliasis Complicating Combined Broad-Spectrum-Antibiotic and Antifungal Therapy

1961 • 10 citations

The effects of nutritional deficiency on response to thiopental.

1953 • 10 citations

Phenylbutazone And Gastric Ulceration in The Guinea Pig II

1959 • 10 citations

The effect of sodium fluoride on responses to various central nervous system agents in rats

1961 • 10 citations

Pharmacologic and toxicologic studies on a new anorexigenic agent—Phendimetrazine

1960 • 10 citations

Effect of Fluorohydrocortisone on Gastrointestinal and Renal Excretion of Cations by the Dog.

1957 • 10 citations

Pharmacologic studies of flumethiazide (ademol).

1960 • 9 citations

Sexual differences in the toxicity of procaine in rats

1961 • 9 citations

Teratogenesis with cancer chemotherapeutic agents

1960 • 9 citations

Effect of chlorpromazine, chlordiazepoxide, diazepam and chlorprothixene on bile and intrabillary pressure in cholecystectomized dogs.

1963 • 9 citations

TOXIC HEPATITIS AND AGRANULOCYTOSIS DUE TO CINCHOPHEN

1957 • 9 citations

Calcium Oxalate Excretion and Hematuria in Vitamin B6-Deficient Rats Fed Phthalylsulfathiazole

1959 • 9 citations

Etiologic factors in 500 cases of bleeding peptic ulcer

1962 • 9 citations

Tolerance of Macacus Rhesus for Isonicotinylhydrazines

1952 • 9 citations

The Changes Produced by Phenylbutazone in the Gastric Secretion of the Guinea Pig I

1959 • 9 citations

A comparison of the mouse and chick in toxicity determinations

1960 • 9 citations

Effects of cortisone on the fetus

1953 • 9 citations

Part VII. Correlation with potential toxicity to man of toxic effects in animals

1962 • 8 citations

QUINDINE IN CHRONIC ATRIAL FIBRILLATION

1960 • 8 citations

Myocardial sodium and potassium content in relation to blood pressure

1959 • 8 citations

RESERPINE-INDUCED GASTROINTESTINAL HEMORRHAGE

1959 • 8 citations

Changes in Phosphorus Metabolism of the Gastrocnemius Muscle in Aging White Rats.

1961 • 8 citations

Effects of Dietary Supplements in Preventing or Augmenting the Production of Cataracts in Rats by 1,4-Dimethane-Sulfonoxybutane

1956 • 8 citations

Recent developments in the understanding of chlorpromazine jaundice.

1957 • 8 citations

STOMATITIS AND PROCTITIS AS MANIFESTATIONS OF MEPROBAMATE IDIOSYNCRASY

1959 • 8 citations

The acute effect of an organic mercurial on the rat kidney: a histochemical study.

1960 • 8 citations

Acute Leukemia After Radioactive Iodine (I131) Therapy for Hyperthyroidism

1960 • 8 citations

Leukocyte and thromboycte antibodies. Current concepts of their origin, identity, and significance.

1962 • 8 citations

Sorbitol, an Inhibitor of Intestinal Absorption of Vitamin B12

1960 • 8 citations

Observations on the use of the trypan blue and skin-twitch tests for measuring local tissue toxicity

1959 • 7 citations

Alteration in toxicity and action of hypoglycemic agents in the rat by sex hormones

1962 • 7 citations

Influence of previous therapy on anesthesia

1962 • 7 citations

Toxicology of nialamide, a new psychotherapeutic agent

1959 • 7 citations

Meprobamate Idiosyncrasy

1958 • 7 citations

Hæmolytic Reaction to Drugs

1962 • 7 citations

TOXICITY OF DICUMAROL: REVIEW OF THE LITERATURE AND REPORT OF TWO CASES

1950 • 7 citations

III. Demonstrationen – Démonstrations

1956 • 7 citations

CLINICAL TRIALS WITH PHENETHYLDIGUANIDE IN SELECTED PATIENTS

1959 • 7 citations

Clinical aspects and types of drug-induced photosensitivity.

1961 • 7 citations

Clinical Science

1962 • 7 citations

METHYLPREDNISOLONE (MEDROL) IN THE TREATMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS

1959 • 7 citations

Prospects for Animal Tests in Experimental Sensitization to Drugs

1962 • 7 citations

The pharmacology of N-benzyl-beta-chloropropionamide (hibicon), a new anticonvulsant.

1953 • 7 citations

Barbital sensitivity in the young rat

1961 • 6 citations

Zoxazolamine Hepatitis

1961 • 6 citations

Radioactivity for Pharmaceutical and Allied Research Laboratories

1960 • 6 citations

GASTROINTESTINAL BLEEDING DURING TOLBUTAMIDE THERAPY

1959 • 6 citations

SIDE-EFFECTS NOTED IN TREATMENT WITH METHYLPREDNISOLONE (MEDROL)

1958 • 6 citations

HEMORRHAGE FROM MULTIPLE SITES ASSOCIATED WITH CHLORPROMAZINE-INDUCED JAUNDICE

1959 • 6 citations

Radioactivity for pharmaceutical and allied research laboratories

1961 • 6 citations

STEROID-INDUCED ADRENAL INSUFFICIENCY AGGRAVATED BY SEVERE MEDICAL ILLNESS

1960 • 6 citations

Endocrine Studies of Chlordiazepoxide.

1961 • 6 citations

Anaphylactic Reaction to Relaxin

1960 • 6 citations

Some pharmacologic and toxicologic properties of metaglycodol

1961 • 5 citations

General Introduction

1962 • 5 citations

The effects of agranulocytic and nonagranulocytic drugs in rabbits concurrently treated with busulfan (Myleran) III. Thiouracil, morphine, and penicillin

1960 • 5 citations

TOXICOLOGICAL STUDIES AND EFFECTIVENESS OF GRISEOFULVIN IN DERMATOMYCOSIS

1959 • 5 citations

Limitations of Animal Tests to Detect Sensitization Reactions in Man

1962 • 5 citations

The effect of certain tranquilizers on intrabiliary pressure of cholecystectomized dogs

1960 • 5 citations

THE EFFECT OF INITIAL TENSION AND LOAD ON THE RESPONSE OF THE NICTITATING MEMBRANE OF THE CAT

1934 • 4 citations

Studies on the toxicity of 2-(4,4′-diacetoxydiphenyl-methyl)pyridine

1960 • 4 citations

Effect of Carbon Tetrachloride on Thioridazine Action and Metabolism.

1961 • 4 citations

THE ALLERGIC DERMATOSES

1957 • 4 citations

Microscopic pathologic changes in tissues of rats and dogs given hydrazine derivatives of isonicotinic acid

1953 • 4 citations

Effect of cortisone, thyroxine and cold on femurs of guinea pigs

1960 • 4 citations

Recent Laboratory Studies and Clinical Observations on Hypersensitivity to Drugs and Use of Drugs in Allergy

1961 • 4 citations

RUPTURED PEPTIC ULCER DURING TRIAMCINOLONE THERAPY

1960 • 4 citations

Skin Reactions to Ingested Drugs

1962 • 4 citations

Speicheldr�senhyperplasien durch Noradrenalin

1962 • 4 citations

Acute Leukemia Following I131 Therapy

1962 • 4 citations

A toxicopathologic study of endobenzyline bromide, a new cholinergic blocking agent

1961 • 3 citations

The toxicity of kanamycin and bacitracin as influenced by stress and sodium chloride

1960 • 3 citations

Unusual Allergic Reaction to Iron-Dextran Complex

1960 • 3 citations

DRUG ERUPTIONS: A REVIEW OF SOME OF THE RECENT LITERATURE

1960 • 3 citations

Prolonged administration studies with chlorpropamide

1960 • 3 citations

Ambenonium in the Treatment of Urinary Retention and Constipation

1959 • 3 citations

Use of Radioiodinated Antipyrine to Measure Liver Function in the Rat.

1961 • 3 citations

Toxicology of marsilid and other amine oxidase inhibitors.

1958 • 3 citations

Pharmacologic and toxicopathologic studies of 1-methyl-5-phenylpyrazolidin-3-one (U-6373)

1959 • 2 citations

Zur Frage einer eventuell bestehenden Lebertoxizität von Iproniazid

1960 • 2 citations

Skin Testing and Desensitization to Drugs

1962 • 2 citations

Effects of Steroid Induced Potassium Depletion on Renal Control of Sodium.

1959 • 2 citations

THE EFFECTS OF PHENYLBUTAZONE AND ACTH ON GASTROINTESTINAL MUCOSA

1959 • 2 citations

Effect of Choline, Heparin and Aureomycin on Fatty Livers of Dogs.

1956 • 2 citations

Triamcinolone in Dermatologic Conditions

1960 • 2 citations

Mechanism of Development of Drug Sensitization of the Skin

1962 • 2 citations

[On incompatibility between monoamine oxidase inhibitors and imipramin (with remarks on the work of O. Eichhorn "Remarks on psychopharmacological combined therapy" in Wien. Med. Wschr. 111, 1961, 307)].

1961 • 2 citations

DEXAMETHASONE THERAPY WITH GASTRIC FUNCTION STUDIES IN PATIENTS WITH RHEUMATOID ARTHRITIS

1960 • 2 citations

A study of the mechanism of the effect of dietary fat in decreasing thiopental sleeping time.

1956 • 1 citations

Beurteilung der unspezifisch-toxischen Wirkungen von Arzneimitteln aus dem Knochenmark der Ratte

1955 • 1 citations

Toxicologic investigation of oxyphencyclimine hydrochloride, a new anticholinergic agent

1959 • 1 citations