Recognition and Allostery in the Mechanism of Antibody Action

The Antibody Problem

1969 • 347 citations

Mouse myeloma proteins with antihapten antibody activity. Protein produced by plasma cell tumor MOPC-315

1968 • 339 citations

Effect of Antigen Binding on the Properties of Antibody

1974 • 182 citations

Structure of the human antibody molecule kol (immunoglobulin G1): An electron density map at 5 Å resolution

1976 • 148 citations

ANTIBODIES TO A UNIQUE REGION IN LYSOZYME PROVOKED BY A SYNTHETIC ANTIGEN CONJUGATE

1969 • 124 citations

Kinetic mapping of the antibody combining site by chemical relaxation spectrometry

1974 • 113 citations

The Structure and Function of Immunoglobulin Domains

1976 • 107 citations

Antigen-induced conformational changes in antibodies and their Fab fragments studied by circular polarization of fluorescence.

1975 • 106 citations

Chemical and immunological characterization of a unique antigenic region in lysozyme

1971 • 95 citations

KINETIC STUDIES OF PROTEIN–DYE AND ANTIBODY–HAPTEN INTERACTIONS WITH THE TEMPERATURE-JUMP METHOD

1962 • 81 citations

Activation of antibody Fc function by antigen-induced conformational changes.

1975 • 70 citations

Spectral changes on binding of oligosaccharides to murine immunoglobulin A myeloma proteins

1973 • 65 citations

Investigation of antigen-antibody kinetics by fluorescence polarization

1968 • 65 citations

X-Ray Diffraction Studies of Immunoglobulins

1975 • 64 citations

Dynamics of hapten-antibody interaction. Studies on a myeloma protein with anti-2, 4-dinitrophenyl specificity

1972 • 63 citations

Crystallographic Structural Studies of a Human Fc-Fragment. I. An Electron-Density Map at 4 Å Resolution and a Partial Model

1976 • 57 citations

Specificity and structure of the myeloma protein produced by mouse plasmacytoma MOPC-460

1971 • 46 citations

Amino acid sequence of a murine immunoglobulin fragment that possesses complement fixing activity

1974 • 37 citations

Conformational changes and complement activation induced upon antigen binding to antibodies

1977 • 37 citations

Specific Excitation Energy Transfer from Antibodies to Dansyl-Labeled Antigen. Studies with the "Loop" Peptide of Hen Egg-White Lysozyme

1971 • 30 citations

Complement activation by a univalent hapten-antibody complex.

1975 • 29 citations

Kinetic mapping of antibody binding sites by chemical relaxation spectroscopy

1972 • 28 citations

Circular dichroism and fluorescence studies of homogeneous antibodies to type III pneumococcal polysaccharide

1975 • 25 citations