Immunotherapy of Recurrent Spontaneous Miscarriage

A Class I Antigen, HLA-G, Expressed in Human Trophoblasts

1990 • 1,417 citations

Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens

1974 • 651 citations

Recurrent miscarriage I: definition and epidemiology

1990 • 581 citations

CONTROLLED TRIAL OF TREATMENT OF RECURRENT SPONTANEOUS ABORTION BY IMMUNISATION WITH PATERNAL CELLS

1985 • 499 citations

DISTURBANCES IN GAMMA GLOBULIN SYNTHESIS AS "EXPERIMENTS OF NATURE"

1956 • 415 citations

Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA Class I molecule.

1990 • 393 citations

Major histocompatibility complex antigens, maternal and paternal immune responses, and chronic habitual abortions in humans

1981 • 370 citations

Lymphocyte subsets in the blood: a diagnostic window on the lymphoid system?

1990 • 350 citations

PREVENTION OF RECURRENT ABORTION WITH LEUCOCYTE TRANSFUSIONS

1981 • 314 citations

Maternal-Fetal Relation

1976 • 292 citations

Preparation of human placental villous surface membrane

1974 • 250 citations

Identification by HLA Typing of Intrauterine-Derived Maternal T Cells in Four Patients with Severe Combined Immunodeficiency

1982 • 249 citations

Cytokine networks in the uteroplacental unit: Macrophages as pivotal regulatory cells

1989 • 240 citations

Lymphocyte subsets in the blood: a diagnostic window on the lymphoid

1990 • 192 citations

Antigen expression by trophoblast populations in the human placenta and their possible immunobiological relevance

1985 • 183 citations

Antigens of human trophoblasts: A working hypothesis for their role in normal and abnormal pregnancies

1978 • 181 citations

Immunological Studies of Human Trophoblast: Markers, Subsets and Functions

1983 • 167 citations

Recurrent miscarriage II: clinical associations, causes, and management

1990 • 167 citations

Pregnancy outcome in human couples with recurrent spontaneous abortions: HLA antigen profiles; HLA antigen sharing; female serum MLR blocking factors; and paternal leukocyte immunization.

1985 • 149 citations

Early Pregnancy Loss: Mechanisms and Treatment

1989 • 149 citations

Immunologic Testing and Immunotherapy in Recurrent Spontaneous Abortion

1986 • 118 citations

Treatment of Recurrent Aborters by Immunization With Paternal Cells—Controlled Trial

1991 • 113 citations

Immunotherapy for Recurrent Spontaneous Abortions in a Chinese Population

1991 • 112 citations

Human Trophoblast‐Specific Surface Antigens Identified Using Monoclonal Antibodies*

1981 • 104 citations

Recurrent Spontaneous Abortion

1989 • 101 citations

MATERNAL IMMUNE RESPONSES TO THE FETUS IN EARLY PREGNANCY AND RECURRENT MISCARRIAGE

1988 • 96 citations

Reproductive immunology

1987 • 87 citations

Prevention of Recurrent Spontaneous Abortion by Intravenous Immunoglobulin

1989 • 87 citations

Immunological studies in recurrent spontaneous abortion: effects of immunization of women with paternal mononuclear cells on lymphocytotoxic and mixed lymphocyte reaction blocking antibodies and correlation with sharing of HLA and pregnancy outcome

1988 • 86 citations

STUDIES ON THE MATERNAL IMMUNE RESPONSE TO PLACENTAL ANTIGENS: ABSENCE OF A BLOCKING FACTOR FROM THE BLOOD OF ABORTION‐PRONE WOMEN

1979 • 81 citations

Immunological Mechanisms of Pregnancy Maintenance and Failure: A Critique of Theories and Therapy

1990 • 81 citations

The human cell-surface glycoproteins HuLy-m5, membrane co-factor protein (MCP) of the complement system, and trophoblast leucocyte-common (TLX) antigen, are CD46.

1990 • 79 citations

Anti-Fetal Allo-Antibody in the Pregnant Female

1983 • 79 citations

Transfusions of leukocyte-rich erythrocyte concentrates: A successful treatment in selected cases of habitual abortion

1986 • 78 citations

Experiments of nature.

1962 • 74 citations

Sharing of human leukocyte antigens in primary and secondary recurrent spontaneous abortions

1990 • 70 citations

Characterization of the human trophoblast-leukocyte antigenic molecules defined by a monoclonal antibody.

1986 • 68 citations

What Do We Know About Spontaneous Abortion Mechanisms?

1989 • 66 citations

Trials and Tribulation in the Treatment of Recurrent Spontaneous Abortion

1991 • 64 citations

Immunological Obstetrics

1992 • 57 citations

Placental immunoregulatory factors

1987 • 57 citations

The alloantibody response of pregnant women and its suppression by soluble HLA antigens and anti-idiotypic antibodies

1991 • 57 citations

Anti-trophoblast antibody responses during normal human pregnancy

1985 • 54 citations

Recurrent abortion: the role of psychotherapy

1988 • 53 citations

A prospective study of spontaneous abortion

1988 • 49 citations

No increased histocompatibility antigen-sharing in couples with idiopathic habitual abortions

1989 • 49 citations

Trophoblast membrane infusion for unexplained recurrent miscarriage

1988 • 47 citations

MATERNAL BLOCKING FACTORS IN HUMAN PREGNANCY ARE FOUND IN PLASMA NOT SERUM

1979 • 47 citations

LACK OF A REQUIREMENT FOR A MATERNAL HUMORAL IMMUNE RESPONSE TO ESTABLISH OR MAINTAIN SUCCESSFUL ALLOGENEIC PREGNANCY

1985 • 47 citations

Immunization by Paternal Leukocytes for Prevention of Primary Habitual Abortion: Results of a Matched Controlled Trial

1990 • 46 citations

Result of Immunotherapy on Patients With Unexplained Recurrent Abortion: A Beneficial Treatment for Patients With Negative Blocking Antibodies

1990 • 45 citations

Human trophoblast cell resistance to decidual NK lysis is due to lack of NK target structure

1990 • 43 citations

Immunological and para-immunological mechanisms in spontaneous abortion: recent insights and future directions

1987 • 41 citations

Paternal Mononuclear Cell Immunization Therapy for Repeated Miscarriage: Predictive Variables for Pregnancy Success

1990 • 41 citations

Trophoblast Antigens in Human Seminal Plasma

1988 • 31 citations

Treatment of Recurrent Spontaneous Abortion by Immunization With Paternal Lymphocytes: Correlates With Outcome

1989 • 28 citations

Immune phagocytosis inhibition by commercial immunoglobulins

1986 • 28 citations

Recurrent habitual aboration, HLA sharing and deliberate immunization with partner's cells: a controversial topic

1986 • 27 citations

Antigens of Human Trophoblast: Trophoblast‐Lymphocyte Cross‐Reactive Antigens on Platelets*

1987 • 23 citations

Workshop A: Unification of Immunotheraphy Protocols

1991 • 22 citations

A Possible Mechanism of Immunotherapy for Patients With Recurrent Spontaneous Abortions

1991 • 22 citations

NONCYTOTOXIC ANTIBODIES TO PATERNAL ANTIGENS IN MATERNAL SERA AND PLACENTAL ELUATES

1984 • 21 citations

Antibodies to trophoblast in normal pregnant and secondary aborting women

1988 • 21 citations

Maternal cell-mediated sensitisation to paternal HLA may occur, but is not a regular event in normal human pregnancy

1987 • 21 citations

Regulation of Immunity to Extraembryonic Antigens in Human Pregnancy

1989 • 20 citations

Identification of selectively solubilised syncytiotrophoblast plasma membrane proteins as potential antigenic targets during normal human pregnancy

1985 • 18 citations

Genetic and immunological factors in human recurrent abortion.

1987 • 15 citations

An investigation of allogeneic pregnancy in multiparous mice subjected to in vivo depletion of CD8 (Ly2)-positive lymphocytes by monoclonal antibody treatment

1988 • 15 citations

Human MHC antigens and paternal leucocyte injections in recurrent spontaneous abortions

1988 • 15 citations

Maternal immune responses to the fetus in early pregnancy and recurrent miscarriage

1989 • 14 citations

Immunotherapy for Recurrent Spontaneous Abortion and its Analogies to Treatment for Cancer

1991 • 14 citations

Antibody reactivity against trophoblast and trophoblast products

1985 • 13 citations

Use of cervical cerclage in patients with recurrent first trimester abortion

1988 • 12 citations

Influence of immunotherapy on the cellular immunity of unexplained recurrent aborters

1991 • 11 citations

Failure of in vitro-expanded hyperimmune cytotoxic T lymphocytes to affect survival of mouse embryos in vivo

1991 • 8 citations

The formation of immune complexes in primiparous and multiparous human pregnancies

1985 • 7 citations

Hypothesis: Blocking Factors and Human Pregnancy: An Alternative Explanation for the Success of Lymphocyte Transfusion Therapy in Abortion‐Prone Women

1986 • 6 citations

Inhibition of binding of anti-CD3 antibodies to paternal lymphocytes correlates with failure of immunotherapy for treatment of recurrent spontaneous abortions

1990 • 6 citations

Early recurrent pregnancy failure: treatment with human chorionic gonadotrophin

1988 • 5 citations

Opinions on Treatment of Women With Habitual Abortion Based on Investigations for Blocking Antibody and Autoantibodies

1991 • 3 citations

Fc receptor blocking antibodies after active immunization for the treatment of recurrent spontaneous abortion

1991 • 2 citations

The Immune System in Disease

1992 • 2 citations

Maternal Immune Responses to the Fetus in Early Pregnancy and Recurrent Miscarriage

1989 • 2 citations