Rat-Rat Hybridoma Formation and Rat Monoclonal Antibodies

Methods in Enzymology , Vol

1966 • 26,261 citations

Continuous cultures of fused cells secreting antibody of predefined specificity

1975 • 17,037 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

[1] Preparation of monoclonal antibodies: Strategies and procedures

1981 • 1,787 citations

A better cell line for making hybridomas secreting specific antibodies

1978 • 1,649 citations

Protides of the Biological Fluids

1969 • 1,623 citations

Production of monoclonal antibodies: Strategy and tactics

1980 • 1,594 citations

Monoclonal Antibodies: Principles and Practice

1996 • 928 citations

Rat monoclonal antitubulin antibodies derived by using a new nonsecreting rat cell line.

1982 • 923 citations

Monoclonal Antibodies: Principles and Practice

1985 • 648 citations

Specific chromosomal translocations and the genesis of B-cell-derived tumors in mice and men

1983 • 517 citations

Rat × rat hybrid myelomas and a monoclonal anti-Fd portion of mouse IgG

1979 • 411 citations

ROLE OF THE THYMUS IN IMMUNE REACTIONS IN RATS

1962 • 264 citations

Light Chain Evolution

1967 • 263 citations

Three classes and four (sub)classes of rat immunoglobulins: IgM, IgA, Ige and IgG₁, IgG_2a, IgG_2b, IgG_2c

1974 • 247 citations

Inhibition of murine T cell‐mediated cytolysis and T cell proliferation by a rat monoclonal antibody immunoprecipitating two lymphoid cell surface polypeptides of 94000 and 180000 molecular weight

1982 • 237 citations

Dimethyl sulfoxide enhances polyethylene glycol-mediated somatic cell fusion

1976 • 199 citations

Fusion of Two Immunoglobulin-producing Myeloma Cells

1973 • 180 citations

Immunocytochemical detection of serotonin with monoclonal antibodies.

1981 • 174 citations

Transplantable immunoglobulin-secreting tumours in rats. IV. Sixty-three IgE-secreting immunocytoma tumours.

1974 • 162 citations

Studies on the transmembrane disposition of the neural cell adhesion molecule N-CAM. A monoclonal antibody recognizing a cytoplasmic domain and evidence for the presence of phosphoserine residues

1984 • 158 citations

THE IMMUNOGLOBULINS OF MICE

1964 • 150 citations

Spontaneous Tumors of the Rat

1930 • 144 citations

Monoclonal antibodies : hybridomas, a new dimension in biological analyses

1980 • 142 citations

Intrasplenic primary immunization for the production of monoclonal antibodies

1984 • 139 citations

Classes and subclasses of rat immunoglobulins: Interaction with the complement system and with staphylococcal protein A

1978 • 135 citations

In vitro and in vivo effector function of rat IgG2a monoclonal anti-S. mansoni antibodies.

1982 • 133 citations

Optimal conditions for the preparation of Fab and F(ab′)2 fragments from monoclonal IgG of different rat IgG subclasses

1983 • 125 citations

Molecular and Biological Aspects of the Acute Allergic Reaction

1976 • 124 citations

Consequences of myc invasion of immunoglobulin loci: Facts and speculation

1983 • 121 citations

Production of Rat Monoclonal Antibodies with the Lou Rat Non Secreting IR983F Myeloma Cell Line

1982 • 120 citations

Rat monoclonal antibodies. I. Rapid purification from in vitro culture supernatants

1984 • 119 citations

Transplantable immunoglobulin‐secreting tumours in rats. I. General features of LOU/Ws1 strain rat immunocytomas and their monoclonal proteins

1972 • 115 citations

THE IMMUNOGLOBULINS OF MICE

1964 • 113 citations

Abnormal Serum Protein and Bone Destruction in Transmissible Mouse Plasma Cell Neoplasm (Multiple Myeloma)

1957 • 100 citations

Subclass restriction of murine antibodies. III. Antigens that stimulate IgG3 in mice stimulate IgG2c in rats.

1980 • 100 citations

Three rat monoclonal antibodies to human C3.

1980 • 92 citations

A Statistical Study of the Occurrence of Spontaneous Tumors in a Large Colony of Rats

1931 • 92 citations

Rat c-myc oncogene is located on chromosome 7 and rearranges in immunocytomas with t(6:7) chromosomal translocation

1983 • 88 citations

Stardardized nomenclature for inbred strains of rats.

1973 • 88 citations

The Production of Anaphylactic Antibody in the Rat

1964 • 83 citations

Transplantable Immunoglobulin-Secreting Tumors in Rats. V. Monoclonal Immunoglobulins Secreted by 250 Ileocecal Immunocytomas in LOU/Wsl Rats2

1973 • 81 citations

STANDARDIZED NOMENCLATURE FOR INBRED STRAINS OF RATS

1973 • 80 citations

Rat immunoglobulins in serum and secretions: Purification of rat IgM, IgA, and IgG and their quantitation in serum, colostrum, milk and saliva

1975 • 78 citations

Mesenteric lymph as a major source of serum IgA in guinea pigs and rats

1973 • 77 citations

Rat monoclonal antibodies. II. A rapid and efficient method of purification from ascitic fluid or serum

1984 • 77 citations

Role of the Thymus in Immune Reactions in Rats

1964 • 72 citations

Identification of J-Chain in Polymeric Immunoglobulins from a Variety of Species by Cross-Reaction with Rabbit Antisera to Human J-Chain

1973 • 70 citations

Monoclonal antibodies. Hybridomas: a New Dimension in Biological Analyses

1981 • 67 citations

MAST CELLS AND ANAPHYLAXIS

1963 • 62 citations

Half-Lives of Two Types of Rat Homocytotropic Antibodies in Circulation and in the Skin

1975 • 60 citations

Differential effect of neonatal injections of anti-mu or anti-delta antibodies on the synthesis of IgM, IgD, IgE, IgA, IgG1, IgG2a, IgG2b, and IgG2c immunoglobulin classes.

1978 • 59 citations

Structure and biologic functions of human IgD. XI. Identification and ontogeny of a rat lymphocyte immunoglobulin having antigenic cross-reactivity with human IgD.

1977 • 57 citations

Purification and characterization of a saliva-interacting cell-wall protein from Streptococcus mutans serotype f by using monoclonal-antibody immunoaffinity chromatography

1985 • 56 citations

Subclass restriction of murine antibodies

1982 • 56 citations

The respective roles of longevity and genetic specificity in the occurrence of spontaneous tumors in the hybrids between two inbred lines of rats.

1946 • 55 citations

Rat IgG subclasses: Differences in affinity to protein A-Sepharose

1981 • 53 citations

Structure and regulation of immunoglobulins: kappa allotypes in the rat have multiple amino-acid differences in the constant region.

1975 • 49 citations

Identification of IgA in Rat Serum and Secretions

1969 • 48 citations

Transplantable IgD Immunoglobulin-Secreting Tumors in Rat

1978 • 47 citations

Fc Receptors for IgE on Normal Rat Lymphocytes

1978 • 47 citations

Non‐random chromosomal changes involving chromosomes 6 and 7 in spontaneous rat immunocytomas

1982 • 45 citations

Plasma-Cell Neoplasms Beginning in the Ileocecal Area in Strain C3H Mice

1957 • 45 citations

RL allotypes of light chains of rat immunoglobulins

1971 • 43 citations

Differential Effect of Neonatal Injections of Anti-µ or Anti-δ Antibodies on the Synthesis of IgM, IgD, IgE, IgA, IgG1, IgG2a, IgG2b, and IgG2c Immunoglobulin Classes

1978 • 43 citations

Inheritance and Strain Distribution of a Rat Immunoglobulin Allotype

1971 • 42 citations

Identification and Some Properties of Rat Secretory Component

1975 • 42 citations

Immunoglobulins of Rat Colostrum

1970 • 40 citations

Serum and secretory immunoglobulins of the rat

1970 • 35 citations

Allotypes of rat immunoglobulins—II. Distribution of the allotypes of kappa and alpha chain loci in different inbred strains of rats

1974 • 35 citations

Transplantable Immunoglobulin‐Secreting Tumours in Rats

1972 • 33 citations

NOMENCLATURE OF HUMAN IMMUNOGLOBULINS.

1965 • 32 citations

The measurement of total serum IgE levels in rats

1977 • 32 citations

Two allotypic specifities of rat immunoglobulin

1971 • 31 citations

Fractionation of rat IgG subclasses and screening for IgG Fc-binding to bacteria

1982 • 31 citations

Differences in the ability of rat IgG subclasses to consume complement in homologous and heterologous serum

1980 • 30 citations

Rat Immunoglobulins in Serum and Secretions: Comparison of IgM, IgA and IgG in Serum, Colostrum, Milk and Saliva of Protein Malnourished and Normal Rats

1975 • 30 citations

Rat monoclonal antibodies

1982 • 29 citations

Rat AL2, AL3, AL4 and AL5 monoclonal antibodies bind to the common acute lymphoblastic leukaemia antigen (CALLA gp 100)

1983 • 29 citations

Allotypes of rat immunoglobulins. I. An allotype at the alpha-chain locus.

1974 • 29 citations

Mouse and rat

1979 • 29 citations

IgE-Myelomas in Rats

1976 • 28 citations

The influence of different adjuvants on the production of IgD and IgE antibodies.

1979 • 28 citations

Rat 7S immunoglobulins: characterization of gamma-2- and gamma-1-anti-haptens antibodies.

1969 • 28 citations

Structure and Biologic Functions of Human IgD

1977 • 27 citations

Immunoglobulin Abnormalities of the Thymectomized Rat

1963 • 27 citations

Valence and Association Constant of Rat Macroglobulin Antibody

1971 • 26 citations

IgE and IgG2a Isotypes in the Rat

2015 • 26 citations

Demonstration of Neutralizing and Non-neutralizing Epitopes on the Trypsin-sensitive Site of Foot-and-Mouth Disease Virus

1984 • 26 citations

Rat immunoglobulins

1979 • 26 citations

Rat monoclonal antibodies VI. Production of IgA secreting hybridomas with specificity for the 2,4-dinitrophenyl (DNP) hapten

1986 • 25 citations

Allotypes of Rat Immunoglobulins

1974 • 25 citations

Proteolysis of rat IgG subclasses by Staphylococcus aureus V8 proteinase

1983 • 22 citations

Detection of Alpha, Kappa and Lambda Chains in Mammalian Immunoglobulins using Fowl Antisera to Human IgA

1971 • 22 citations

Structure and Biological Functions of Human IgD

1975 • 22 citations

Transplantable immunoglobulin-secreting tumors in rats—III

1973 • 22 citations

Studies on the Conformation of Purified Human and Canine γA-Globulins and Equine γT-Globulin by Optical Rotatory Dispersion

1968 • 21 citations

Heterogeneity of Rat Immunoglobulins

1965 • 21 citations

Immunoglobulin allotype in the rat: localization of the specificity to the light chain.

1969 • 20 citations

Production and characterization of monoclonal antibodies to β-galactoside-binding lectin of bovine heart muscle. Direct evidence that haemagglutinating activity is associated with a 13kDa protein

1984 • 19 citations

Ray γM immunoglobulin: Isolation and some biological characteristics

1972 • 19 citations

Rat hybridoma antibodies against canine parvovirus

1982 • 19 citations

Rat monoclonal antibodies. IV. Easy method for in vitro production

1985 • 19 citations

Organ- und Blutver�nderungen beim KG-13-Plasmocytom des Goldamsters

1964 • 18 citations

Shared idiotope on monoclonal anti-Ia.7 antibodies reactive with determinants in a structural domain of the I-E molecules.

1984 • 18 citations

Characterization of three feline paraproteins.

1972 • 17 citations

Allotypes of rat immunoglobulins—III: An allotype of the γ2b-chain locus

1975 • 17 citations

B cell subpopulations in the mouse: Analysis with monoclonal antibodies NIM‐R2 and NIM‐R3

1982 • 16 citations

Characterization of Rat IgA and Its Non-Identity with the Anaphylactic Antibody

1966 • 16 citations

Antigenic similarities of rat and mouse IgG subclasses associated with anti-carbohydrate specificities

1980 • 16 citations

Characterization of Three Feline Paraproteins

1972 • 15 citations

Rat (and mouse) monoclonal antibodies V.A. simple automated technique of antigen purification by immunoaffinity chromatography

1986 • 15 citations

Evidence that Static but Not Recirculating B Cells are Responsible for Antibody Production Against Dinitrophenol on Neutral Polysaccharide, A TI-2 Antigen

1985 • 15 citations

Transplantable Lymphosarcomata of the Mesenteric Lymph Nodes of Rats

1940 • 14 citations

Lambda light chains in rat immunoglobulins

1973 • 14 citations

A rat monoclonal antibody against mouse α and β interferon of all molecular weight species

1982 • 13 citations

Allotypic Specificity of Serum Protein in Inbred Strains of Rats

1967 • 13 citations

Production of monoclonal anti-glomerular basement membrane antibodies during autoimmune glomerulonephritis

1984 • 13 citations

Preparation of an antiserum specific for rat reagin (rat E?).

1971 • 13 citations

[59] The use of rat monoclonal antibodies to characterize, quantify, and purify polyclonal or monoclonal mouse IgM

1986 • 13 citations

Immunoglobulin production in nude rats with special attention to the IgE isotype.

1980 • 12 citations

Oral Feeding of Ovalbumin Can Make Rats Tolerant to an Intraperitoneal Injection of Dinitrophenylated Ovalbumin and Bordetella pertussis Vaccine

1977 • 12 citations

Rat Ileocecal Immunocytoma. An Ultrastructural Study With Special Attention to the Presence of Viral Particles<xref ref-type="fn" rid="FN2">2</xref>

1978 • 11 citations

Detection of Five Components Having Antibody Activity in Rat Antisera.

1967 • 11 citations

Antibody specificity and antigen characterization of rat monoclonal antibodies against Streptococcus mutans cell wall-associated protein antigens

1985 • 10 citations

Incidence of Spontaneous Ileocecal Immunocytomas in Hybrids of LOU/C Rats and Rat Strains With Low Spontaneous Tumor Incidence: Brief Communication 2 3

1978 • 10 citations

Tryptic cleavage of rat IgG: A comparative study between subclasses

1981 • 9 citations

The nature of ‘species-specific’ amino acid residues

1975 • 9 citations

The Federation of American Societies of Experimental Biology

1928 • 9 citations

Partial amino acid sequences of ?-chains of rat immunoglobulins: Genetic and evolutionary implications

1976 • 8 citations

IgM Production in Rats Infected With Moloney Leukemia Virus 2

1973 • 7 citations

Decrease in the incidence of malignant ileo-caecal immunocytoma in LOU/C rats after surgical removal of the ileo-caecal lymph nodes

1977 • 7 citations

Rat Hybridoma Technology: Culturing of Rat Myeloma Cell Line IR983F Prior to Cell Fusion

1983 • 7 citations

Obtention of rat monoclonal antibodies reactive with human leukaemic lymphoblasts.

1983 • 6 citations

Oncogenes and B-lymphocyte neoplasia

1983 • 6 citations

Genetic Control of the IgE Reaginic Immune Response

1981 • 5 citations

Differences in sensitivity to reduction of rat immunoglobulin IgG subclasses

1979 • 5 citations

Tryptic and plasmic cleavage of a rat myeloma IgD

1981 • 4 citations

Studies on the incidence of rat ileocecal malignant immunocytoma: Vertical transmission of the high tumour incidence

1980 • 4 citations

Allotypic determinants (Igh-3) associated with the IgG2c subclass of rat immunoglobulins

1984 • 3 citations

Genetic control of the IgE reaginic immune response and of its radiation-induced enhancement.

1981 • 2 citations

Le leucosarcome du rat

2015 • 2 citations