Interaction of malonyl-CoA and 2-tetradecylglycidyl-CoA with mitochondrial carnitine palmitoyltransferase I.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Carnitine--metabolism and functions

1983 • 1,620 citations

Regulation of Hepatic Fatty Acid Oxidation and Ketone Body Production

1980 • 1,430 citations

The Enzymes of Biological Membranes

1985 • 1,362 citations

A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis.

1977 • 705 citations

Carnitine palmitoyltransferase I. The site of inhibition of hepatic fatty acid oxidation by malonyl-CoA.

1978 • 586 citations

Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

1983 • 549 citations

The effect of fasting on the activity of liver carnitine palmitoyltransferase and its inhibition by malonyl-CoA

1981 • 250 citations

Carnitine Palmityltransferase

1972 • 220 citations

Hepatic malonyl-CoA levels of fed, fasted and diabetic rats as measured using a simple radioisotopic assay.

1978 • 193 citations

The Enzymes of Biological Membranes

1976 • 176 citations

The role of acylcarnitine esters and carnitine palmityltransferase in the transport of fatty acyl groups across mitochondrial membranes.

1965 • 162 citations

Identification of 2-tetradecylglycidyl coenzyme A as the active form of methyl 2-tetradecylglycidate (methyl palmoxirate) and its characterization as an irreversible, active site-directed inhibitor of carnitine palmitoyltransferase A in isolated rat liver mitochondria.

1984 • 151 citations

Purification and Properties of Carnitine Octanoyltransferase and Carnitine Palmitoyltransferase from Rat Liver1

1983 • 149 citations

Carnitine palmitoyltransferase and carnitine octanoyltransferase activities in liver, kidney cortex, adipocyte, lactating mammary gland, skeletal muscle and heart

1981 • 143 citations

Interaction of malonyl-CoA and related compounds with mitochondria from different rat tissues. Relationship between ligand binding and inhibition of carnitine palmitoyltransferase I

1983 • 124 citations

Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA

1982 • 100 citations

Isolation and purification of mitochondrial carnitine octanoyltransferase activities from beef heart.

1981 • 86 citations

Comparison of Properties of Carnitine Palmitoyltransferase I with Those of Carnitine Palmitoyltransferase II, and Preparation of Antibodies to Carnitine Palmitoyltransferases

1973 • 86 citations

Studies on carnitine palmitoyl transferase: The similar nature of CPTI (inner form) and CPTO (outer form)

1980 • 81 citations

Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I

1984 • 78 citations

Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity

1984 • 67 citations

Inhibition of mitochondrial carnitine palmitoyl transferase by 2-tetradecylglycidic acid (McN-3802) ()

1980 • 64 citations

[40] 2-Tetradecylglycidic acid

1981 • 63 citations

Sigmoid kinetics of purified beef heart mitochondrial carnitine palmitoyltransferase. Effect of pH and malonyl-CoA.

1984 • 54 citations

Inhibition of Mitochondrial Carnitine Palmitoyl Transferase A in Vivo with Methyl 2-Tetradecylglycidate (Methyl Palmoxirate) and Its Relationship to Ketonemia and Glycemia

1985 • 50 citations

Biosynthesis of Carnitine Octanoyltransferase and Carnitine Palmitoyltransferase1

1983 • 39 citations

Inhibition of mitochondrial β-oxidation at the stage of carnitine palmitoyltransferase I by the coenzyme A esters of some substituted hypoglycaemic oxiran-2-carboxylic acids

1981 • 26 citations