Genetic variability and adaptation to stress

DNA Repair and Mutagenesis

2006 • 4,725 citations

Evolutionary Rate at the Molecular Level

1968 • 3,608 citations

Bacterial evolution.

1987 • 2,521 citations

DNA repair and mutagenesis

1996 • 2,289 citations

MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY

1996 • 1,485 citations

A constant rate of spontaneous mutation in DNA-based microbes.

1991 • 1,194 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

Adaptive evolution of highly mutable loci in pathogenic bacteria

1994 • 764 citations

The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants

1989 • 728 citations

The Red Queen: sex and the evolution of human nature

1994 • 671 citations

Adaptive reversion of a frameshift mutation in Escherichia coli.

1991 • 495 citations

Stress-Inducible Cellular Responses

1995 • 337 citations

Interspecies gene exchange in bacteria: The role of SOS and mismatch repair systems in evolution of species

1995 • 298 citations

Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs.

1994 • 251 citations

COMPETITION BETWEEN HIGH AND LOW MUTATING STRAINS OF ESCHERICHIA COLI

1983 • 246 citations

A set of lacZ mutations in Escherichia coli that allow rapid detection of specific frameshift mutations.

1990 • 211 citations

cAMP-dependent SOS induction and mutagenesis in resting bacterial populations.

1995 • 197 citations

Depletion of the cellular amounts of the MutS and MutH methyl-directed mismatch repair proteins in stationary-phase Escherichia coli K-12 cells

1996 • 167 citations

Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates.

1991 • 153 citations

Mechanisms and consequences of DNA damage processing

1987 • 152 citations

Genetic barriers among bacteria

1996 • 149 citations

The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors.

1989 • 149 citations

Control of large chromosomal duplications in Escherichia coli by the mismatch repair system.

1991 • 140 citations

The Recombination of Genetic Material

1988 • 116 citations

Competition Between High and Low Mutating Strains of Escherichia coli

1983 • 112 citations

Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

1995 • 106 citations

Rearrangement/hypermutation/gene conversion: when, where and why?

1996 • 100 citations

HYPER-RECOMBINING RECIPIENT STRAINS IN BACTERIAL CONJUGATION

1986 • 98 citations

Selection against hypermutability in Escherichia coli during long term evolution

1984 • 90 citations

Incidence of mutator strains in Escherichia coli and coliforms in nature

1981 • 87 citations

So, what about the molecular clock hypothesis?

1993 • 84 citations

Mismatch recognition in chromosomal interactions and speciation

1993 • 84 citations

MISMATCH REPAIR MUTATIONS OF ESCHERICHIA COLI K12 ENHANCE TRANSPOSON EXCISION

1985 • 83 citations

Editing DNA replication and recombination by mismatch repair: from bacterial genetics to mechanisms of predisposition to cancer in humans

1995 • 73 citations

Plaque color method for rapid isolation of novel recA mutants of Escherichia coli K-12: new classes of protease-constitutive recA mutants

1985 • 67 citations

Identification and characterization of the mutL and mutS gene products of Salmonella typhimurium LT2

1985 • 65 citations

OBSERVATIONS ON TWO TYPES OF GENETIC INSTABILITY IN ESCHERICHIA COLI

1960 • 64 citations

Updating the Theory of Mutation

1983 • 59 citations

Induction of the SOS Response by IS1 Transposase

1994 • 54 citations

Multicopy single‐stranded DNA of Escherichia coli enhances mutation and recombination frequencies by titrating MutS protein

1996 • 47 citations

Saturation of mismatch repair in the mutD5 mutator strain of Escherichia coli

1989 • 46 citations

Respiration, Growth and Viability of Repair-deficient Mutants ofEscherichia Coliafter Ultraviolet Irradiation

1974 • 46 citations

The generation of variation in bacterial genomes

1995 • 44 citations

Inducible DNA repair and differentiation in Bacillus subtilis: interactions between global regulons

1992 • 44 citations

SOS induction in Escherichia coli by infection with mutant filamentous phage that are defective in initiation of complementary-strand DNA synthesis

1992 • 39 citations

Multicopy single‐stranded DNAs with mismatched base pairs are mutagenic in Escherichia coli

1994 • 37 citations

Effect of mutations in SOS genes on UV-induced precise excision of Tn10 in Escherichia coli

1993 • 35 citations

Restriction in vivo

1980 • 35 citations

Duplication mutation as an SOS response in Escherichia coli: enhanced duplication formation by a constitutively activated RecA.

1989 • 35 citations

Tn10 transposition promotes RecA-dependent induction of a lambda prophage.

1988 • 35 citations

Death and transfiguration among bacteria

1992 • 32 citations

Inhibition of the recBCD-dependent activation of Chi recombinational hot spots in SOS-induced cells of Escherichia coli

1992 • 31 citations

Excision and transposition of Tn5 as an SOS activity in Escherichia coli.

1991 • 30 citations

Phosphate starvation and low temperature as well as ultraviolet irradiation transcriptionally induce the Escherichia coli LexA‐controlled gene sfiA

1993 • 30 citations

pR plasmid replication provides evidence that single-stranded DNA induces the SOS system in vivo

1993 • 30 citations

Stress-inducible cellular responses

1997 • 27 citations

In vitro reconstitution of homologous recombination reactions

1994 • 25 citations

In vitro UV mutagenesis associated with nucleotide excision-repair gaps in Escherichia coli.

1994 • 24 citations

Bacterial shock responses

1993 • 18 citations

Induction of the inhibitor of RecBCD enzyme inEscherichia coli is alexA-independent SOS response

1990 • 11 citations

Induction of Recombination-Related Functions (SOS Functions) in Response to DNA Damage

1988 • 9 citations

Increase in plasmid transformation efficiency in SOS-induced Escherichia coli cells

1988 • 8 citations