[15] Chemical synthesis of deoxyoligonucleotides by the phosphoramidite method

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

1981 • 1,881 citations

Synthesis of deoxyoligonucleotides on a polymer support

1981 • 870 citations

Gene Synthesis Machines: DNA Chemistry and Its Uses

1985 • 761 citations

An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides

1983 • 504 citations

β-Cyanoethyl N,N-dialkylamino/N-morpholinomonochloro phosphoamidites, new phosphitylating agents facilitating ease of deprotection and work-up of synthesized oligonucleotides

1983 • 266 citations

In situactivation of bis-dialkylaminophosphines—a new method for synthesizing deoxyoligonucleotides on polymer supports

1984 • 241 citations

Hindered dialkylamino nucleoside phosphite reagents in the synthesis of two DNA 51-mers

1983 • 227 citations

Nucleotide chemistry. 16. Amidine protecting groups for oligonucleotide synthesis

1986 • 181 citations

Chemical and enzymatic synthesis of gene fragments

1983 • 174 citations

A microchemical facility for the analysis and synthesis of genes and proteins

1984 • 134 citations

The synthesis of oligodeoxyprimidines on a polymer support

1980 • 129 citations

Syringe method for stepwise chemical synthesis of oligonucleotides

1982 • 123 citations

Dialkylformamldines: depurination resistant N⁶-protecting group for deoxyadenosine

1983 • 123 citations

New effective method for the synthesis of oligonucleotides via phosphotriester intermediates

1982 • 113 citations

Recovery and recycling of synthetic units in the construction of oligodeoxyribonucleotides on solid supports

1981 • 59 citations

Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides

1985 • 57 citations

Chemical synthesis of branched RNA

1986 • 53 citations

A simple and efficient preparation of deoxynucleoside phosphoramidites in situ

1984 • 44 citations

N6(N-methyl-2-pyrrolidine amidine)deoxyadenosine - a new deoxynucleoside protecting group

1983 • 39 citations

Chemical Synthesis and biochemical reactivity of bacterlophage bambda p_Rpromoter

1983 • 35 citations

Cylci diacyl groups for protection of the N⁶-amino group of deoxyadenosine in oligodeoxynucleotide synthesis

1984 • 33 citations

Base Modification and the Phosphoramidite Approach

1987 • 18 citations