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Immunomodulation by Cyclophosphamide and its Effect on Eradication of Established Tumors

Data up to Jan 2025

Published1984
Citations4
References28

Total Citations Per Year

Abstract

References (28)

Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells.

1982 • 640 citations

Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.

1975 • 434 citations

Regulation of Delayed-Type Hypersensitivity Reactions by Cyclophosphamide-Sensitive T Cells

1978 • 146 citations

Regulation of specific cell-mediated cytotoxic response against SV40-induced tumor associated antigens by depletion of suppressor T cells with cyclophosphamide in mice.

1979 • 120 citations

Neuartige Krebs-Chemotherapeutika aus der Gruppe der zyklischen N-Lost-Phosphamidester

1958 • 118 citations

Hapten-specific IgE antibody responses in mice. VI. Selective enhancement of IgE antibody production by low doses of X-irradiation and by cyclophosphamide.

1976 • 117 citations

Cooperation between cyclophosphamide tumoricidal activity and host antitumor immunity in the cure of mice bearing large MOPC-315 tumors.

1981 • 100 citations

Importance of timing in cyclophosphamide therapy of MOPC-315 tumor-bearing mice.

1980 • 92 citations

Hapten-Specific IgE Antibody Responses in Mice

1976 • 78 citations

Relative susceptibilities of T cell subsets involved in delayed-type hypersensitivity to sheep red blood cells to the in vitro action of 4-hydroperoxycyclophosphamide.

1980 • 61 citations

Role of antitumor immunity in cyclophosphamide-induced rejection of subcutaneous nonpalpable MOPC-315 tumors.

1982 • 59 citations

Contribution of host immunity to cyclophosphamide therapy of a chemically‐induced murine sarcoma

1973 • 51 citations

ADOPTIVE CHEMOIMMUNOTHERAPY OF CANCER IN ANIMALS: A REVIEW OF RESULTS, PRINCIPLES, AND PROBLEMS*

1976 • 51 citations

Detection of early and delayed antitumor effects following curative adoptive chemoimmunotherapy of established leukemia.

1980 • 49 citations

Differential sensitivity to cyclophosphamide of helper T cells for humoral responses and suppressor T cells for delayed‐type hypersensitivity

1980 • 42 citations

Effectiveness of murine leukemia chemotherapy according to the immune state

1977 • 37 citations

Antigen-Induced Cyclophosphamide-Resistant Suppressor T Cells Inhibit the in Vitro Generation of Cytotoxic Cells from One-Way Mixed Leukocyte Reactions

1977 • 36 citations

Differential tumor immunogenicity of L1210 and its sublines. I. Effect of an increased antigen density on tumor cell surfaces on primary B cell responses in vitro.

1977 • 28 citations

Therapy of the Murine Plasmacytoma MOPC 104E: Role of the Immune Response<xref ref-type="fn" rid="FN2">2</xref>

1978 • 28 citations

INDUCTION OF TUMOR IMMUNITY BY INTRATUMORAL CHEMOTHERAPY

1976 • 27 citations

Augmentation of antitumor cytotoxicity in MOPC-315 tumor bearer spleen cells by depletion of glass-adherent cells prior to in vitro activation.

1979 • 26 citations

Analysis of synergy between cyclophosphamide Therapy and Immunity Against a Mouse Tumour

1978 • 25 citations

Augmentation of antitumor cytotoxicity of MOPC-315 tumor bearer spleen cells by depletion of dinitrophenol-adherent cells prior to in vitro immunization.

1979 • 22 citations

Differential Tumor Immunogenicity of DBA/2 Mouse Lymphoma L1210 and Its Sublines. II. Increased Expression of Tumor-Associated Antigens on Subline Cells Recognized by Serologic and Transplantation Methods<xref ref-type="fn" rid="FN2">2</xref>

1979 • 18 citations

Differential Tumor Immunogenicity of L1210 and its Sublines

1977 • 17 citations

The application of an in vitro cytotoxicity test to studies of the effects of drugs on the cellular immune response in mice. I. Primary response.

1972 • 16 citations

The Application of an in Vitro Cytotoxicity Test to Studies of the Effects of Drugs on the Cellular Immune Response in Mice

1972 • 11 citations

Possible mechanism of target cell resistance in antibody‐dependent cellular cytotoxicity

1980 • 5 citations

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