Chapter 2 The Extracellular Matrix: A Dynamic Component of the Developing Embryo

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Principles of biochemistry

1978 • 5,242 citations

A NEW SPECIFIC COLOR REACTION OF HEXURONIC ACIDS

1947 • 2,137 citations

ORGANIZATION FOR PHYSIOLOGICAL HOMEOSTASIS

1929 • 1,692 citations

Enzymatic Methods for the Determination of Small Quantities of Isomeric Chondroitin Sulfates

1968 • 1,377 citations

Purification and Properties of Bacterial Chondroitinases and Chondrosulfatases

1968 • 1,238 citations

The synthesis of complex carbohydrates by multiglycosyltransferase systems and their potential function in intercellular adhesion

1970 • 1,208 citations

Differential staining of acid glycosaminoglycans (mucopolysaccharides) by Alcian blue in salt solutions

1965 • 1,065 citations

Ruthenium red and violet. II. Fine structural localization in animal tissues

1971 • 862 citations

The Chromatographic Separation and Amino Acid Composition of the Subunits of Several Collagens^*

1963 • 706 citations

ELECTRON MICROSCOPE OBSERVATIONS ON THE CARBOHYDRATE-RICH CELL COAT PRESENT AT THE SURFACE OF CELLS IN THE RAT

1967 • 660 citations

Proteinpolysaccharide Complex from Bovine Nasal Cartilage

1969 • 655 citations

The specific interaction of hyaluronic acid with cartilage proteoglycans

1972 • 643 citations

MORPHOLOGICAL ASPECTS OF EXTRACELLULAR POLYSACCHARIDES

1963 • 634 citations

Chemistry and molecular biology of the intercellular matrix

1970 • 626 citations

[Microdetermination of hydroxyproline with chloramine-T and p-dimethylaminobenzaldehyde].

1958 • 626 citations

The Estimation of Polypeptide Chain Molecular Weights by Gel Filtration in 6 M Guanidine Hydrochloride

1969 • 603 citations

ULTRASTRUCTURE OF HUMAN LEUKOCYTES AFTER SIMULTANEOUS FIXATION WITH GLUTARALDEHYDE AND OSMIUM TETROXIDE AND "POSTFIXATION" IN URANYL ACETATE

1968 • 566 citations

The Chemistry and Structure of Collagen

1971 • 555 citations

Mikrobestimmung von Hydroxyprolin mit Chloramin-T undp-Dimethylaminobenzaldehyd

1958 • 550 citations

Collagen Polymorphism: Characterization of Molecules with the Chain Composition [α1(III)] ₃ in Human Tissues

1974 • 524 citations

Structure and Biosynthesis of Basement Membranes

1973 • 519 citations

Characterization of collagen peptides by sodium dodecylsulfate-polyacrylamide electrophoresis

1971 • 517 citations

A CORRELATIVE STUDY OF THE HISTOCHEMICAL PROPERTIES OF RODENT ACID MUCOPOLYSACCHARIDES

1960 • 475 citations

Book Review: Treatise on Collagen

1969 • 442 citations

Glycoproteins

1970 • 408 citations

Isolation and characterization of a chick cartilage collagen containing three identical chains

1971 • 395 citations

Cross-Linking of Collagen

1973 • 384 citations

The effect of ascorbic acid on collagen polypeptide synthesis and proline hydroxylation during the growth of cultured fibroblasts

1972 • 377 citations

Physical Properties and Polydispersity of Proteoglycan from Bovine Nasal Cartilage

1970 • 357 citations

Hyaluronate production and removal during corneal development in the chick

1971 • 356 citations

Embryonic development of the heart. I. A light and electron microscopic study of myocardial development in the early chick embryo

1968 • 347 citations

CHICK CARTILAGE COLLAGEN: A NEW TYPE OF α1 CHAIN NOT PRESENT IN BONE OR SKIN OF THE SPECIES

1969 • 329 citations

Distribution of periodic acid-reactive carbohydrates in the adult rat

1950 • 316 citations

Morphological and Histochemical Aspects of Glycoproteins at the Surface of Animal Cells

1971 • 314 citations

DEPENDENCE OF SALIVARY EPITHELIAL MORPHOLOGY AND BRANCHING MORPHOGENESIS UPON ACID MUCOPOLYSACCHARIDE-PROTEIN (PROTEOGLYCAN) AT THE EPITHELIAL SURFACE

1972 • 304 citations

Determination of glycosaminoglycans (mucopolysaccharides) from tissues on the microgram scale

1964 • 299 citations

Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human skin and cartilage collagen

1971 • 292 citations

Isolation of a collagen from basement membranes containing three identical α-chains

1971 • 287 citations

EPITHELIAL COLLAGENS AND GLYCOSAMINOGLYCANS IN THE EMBRYONIC CORNEA

1974 • 280 citations

Polysaccharides associated with the exterior surface of epithelial cells: Kidney, intestine, brain

1966 • 278 citations

STUDIES ON THE FORMATION OF COLLAGEN

1958 • 241 citations

Structure and Metabolism of Connective Tissue Proteins

1972 • 240 citations

Hyaluronate turnover during chondrogenesis in the developing chick limb and axial skeleton

1972 • 240 citations

The Biosynthesis of Collagen

1972 • 235 citations

The Surface Coats of Animal Cells

1970 • 220 citations

DISC ELECTROPHORESIS OF COLLAGEN COMPONENTS

1964 • 212 citations

Ageing of Human Cartilage

1959 • 207 citations

GLYCOSAMINOGLYCAN SYNTHESIS BY EMBRYONIC INDUCTORS: NEURAL TUBE, NOTOCHORD, AND LENS

1974 • 206 citations

Presence of a ‘cell coat’ rich in carbohydrate at the surface of cells in the rat

1966 • 199 citations

Principles of Biochemistry

1964 • 199 citations

Characterization of Chick Bone Collagen and Compositional Changes Associated with Maturation

1967 • 195 citations

The chemical and histochemical properties of Alcian Blue

1964 • 193 citations

Isolation of two distinct collagens from chick cartilage

1970 • 193 citations

Electron microscopic demonstration of proteoglycans in guinea pig epiphyseal cartilage

1973 • 189 citations

Secretion of collagen by embryonic neuroepithelium at the time of spinal cord-somite interaction

1971 • 188 citations

The effect of chondroitin sulphate–protein on the formation of collagen fibrils in vitro

1968 • 181 citations

SECRETION OF COLLAGEN BY CORNEAL EPITHELIUM

1973 • 179 citations

METACHROMASIA; CHEMICAL THEORY AND HISTOCHEMICAL USE

1956 • 177 citations

SUBCELLUAR SITES FOR SYNTHESIS OF CHONDROMUCOPROTEIN OF CARTILAGE

1968 • 166 citations

Multiple aggregation factors in cartilage proteoglycan (Short Communication)

1973 • 162 citations

Hyaluronate and Hyaluronidase in Morphogenesis and Differentiation

1973 • 161 citations

ACID MUCOPOLYSACCHARIDE (GLYCOSAMINOGLYCAN) AT THE EPITHELIAL-MESENCHYMAL INTERFACE OF MOUSE EMBRYO SALIVARY GLANDS

1972 • 160 citations

Acid mucopolysaccharide patterns in aging human cartilage.

1966 • 154 citations

Reaction of heparitin sulfate with nitrous acid

1968 • 152 citations

Isolation and characterization of the cyanogen bromide peptides from the .alpha.1(II) chain of chick cartilage collagen

1971 • 145 citations

The Separation and Characterization of the α- and β-Components of Calf Skin Collagen

1960 • 142 citations

The biosynthesis of chondroitin-sulfate protein complex.

1965 • 134 citations

Origin and Role of Collagen in the Embryo

1973 • 132 citations

Glycosaminoglycans and Epithelial Organ Formation

1973 • 131 citations

Collagen Heterogeneity

1972 • 129 citations

Sulfated mucopolysaccharide synthesis during the development of Rana pipiens

1973 • 124 citations

Synthesis of sulfated glycosaminoglycans by embryonic corneal epithelium

1973 • 122 citations

Collagen heterogeneity within different growth regions of long bones of rachitic and nonrachitic chicks

1972 • 118 citations

The presence of organic phosphorus in collagens and gelatins

1964 • 115 citations

The loss of phenotypic traits by differentiated cells

1967 • 112 citations

THE REMOVAL BY PHOSPHOLIPASE C OF A LAYER OF LANTHANUM-STAINING MATERIAL EXTERNAL TO THE CELL MEMBRANE IN EMBRYONIC CHICK CELLS

1967 • 111 citations

On the inhibition of lysyl oxidase by β-aminopropionitrile

1972 • 108 citations

Characterization of the α-chains of chick skin collagen and the nature of the amino-terminal cross-link region

1969 • 108 citations

Collagen synthesis by articular chondrocytes in monolayer culture

1972 • 108 citations

HISTOCHEMICAL DIFFERENTIATION OF MAMMALIAN MUCOPOLYSACCHARIDES

1963 • 106 citations

Cyanogen bromide peptides from insoluble skin and dentin bovine collagens

1973 • 106 citations

The thermal denaturation of collagen in solution and its structural implications

1959 • 103 citations

The Limited Cleavage of Native Collagen with Chymotrypsin, Trypsin, and Cyanogen Bromide^*

1966 • 102 citations

The collagen of chick embryonic notochord

1973 • 101 citations

The Formation of Unsaturated Disacharides from Mucopolysaccharides and Their Cleavage to α-Keto Acid by Bacterial Enzymes

1960 • 100 citations

The distribution of glycosaminoglycans in the axial region of the developing chick embryo. I. Histochemical analysis

1970 • 99 citations

Synthesis of Proteochondroitin Sulfate by Normal, Nanomelic, and 5-Bromodeoxyuridine-Treated Chondrocytes in Cell Culture

1972 • 99 citations

Glycosaminoglycan synthesis by the early embryonic chick heart

1973 • 94 citations

A Primer on Connective Tissue Biochemistry

1969 • 93 citations

Changes in Cell and Organ Shape during Early Development of the Ocular Lens

1973 • 93 citations

Protein Subunits: A Table (Second Edition)

1969 • 92 citations

The Separation of New Forms of the Proteinpolysaccharides of Bovine Nasal Cartilage

1966 • 92 citations

Isolation and characterization of the peptides derived from the α1 chain of chick bone collagen after cyanogen bromide cleavage

1969 • 90 citations

The Sulfation of Chondroitin Sulfate in Embryonic Chick Cartilage Epiphyses

1969 • 89 citations

The incorporation of [14C]glycine into the subunits of collagens from normal and lathyritic animals

1963 • 88 citations

Comparative study of the localization of incorporated 14C-labeled amino acids and 35SO4 in the sea urchin ovary, egg and embryo

1961 • 83 citations

Sulfated extracellular matrix production in the embryonic heart and adjacent tissues

1970 • 82 citations

Environmental enhancement of in vitro chondrogenesis

1971 • 79 citations

Utilization of S35-Labelled Sodium Sulphate in the Synthesis of Chondroitin Sulphuric Acid, Taurine, Methionine and Cystine.

1952 • 77 citations

Isolation and characterization of the cyanogen bromide peptides from the α1 and α2 chains of human skin collagen

1970 • 75 citations

The biochemical and ultrastructural demonstration of collagen during early heart development

1974 • 74 citations

A Comparison of Proteinpolysaccharides of Bovine Nasal Cartilage Isolated and Fractionated by Different Methods

1970 • 74 citations

Developmental regulation: aspects of cell differentiation,

1973 • 72 citations

A primer on connective tissue biochemistry

1968 • 70 citations

Characterization of the cyanogen bromide peptides from the α1 chain of chick skin collagen

1969 • 70 citations

Collagen Synthesis in vitro by Embryonic Spinal Cord Epithelium

1973 • 69 citations

Characterization of the cyanogen bromide peptides from the α2 chain of chick skin collagen

1969 • 69 citations

Isolation and characterization of cyanogen bromide peptides from basement membrane collagen

1972 • 68 citations

Developing boundary (basement) membranes in the chick embryo

1967 • 67 citations

The fine structure of perinotochordal microfibrils in control and enzyme‐treated chick embryos

1971 • 65 citations

Collagen and mucopolysaccharide biosynthesis in mass cultures and clones of chick corneal fibroblasts in vitro

1970 • 65 citations

Biosynthesis of Cartilage Collagen

1973 • 64 citations

GAMMA TROPOCOLLAGEN: A REVERSIBLY DENATURABLE COLLAGEN MACROMOLECULE

1961 • 64 citations

Bone collagen metabolism in vitamin D deficiency (Short Communication)

1973 • 64 citations

Inhibition of cartilage development in organ cultures of chick somites by the thymidine analog, 5-bromo-2′-deoxyuridine

1972 • 62 citations

Extracellular connective tissue fibrils in the chick embryo

1968 • 61 citations

Chondrogenesis: Genotypic and phenotypic expression

1968 • 58 citations

Interstitial bodies in the early chick embryo

1970 • 58 citations

AUTORADIOGRAPHIC STUDIES OF THE UTILIZATION OF S35-SULFATE BY THE CHICK EMBRYO

1957 • 58 citations

Effects of enzymes and EDTA on ruthenium red and concanavalin A labeling of the cell surface

1973 • 57 citations

Connective Tissue Proteinpolysaccharides

1967 • 57 citations

DISTRIBUTION OF MUCOSUBSTANCES IN THE DEVELOPING RAT HEART

1972 • 56 citations

CELLULAR DIFFERENTIATION AND THE AGING PROCESS IN CARTILAGINOUS TISSUES

1968 • 55 citations

Heterogeneity of the α Chains of Rat Skin Collagen and Its Relation to the Biosynthesis of Cross-Links^*

1966 • 55 citations

Accumulation of a collagen precursor in the skin of penicillamine-treated rats

1965 • 55 citations

Control of phenotypic expression in cultured chondrocytes: Investigations on the mechanism

1970 • 50 citations

Biosynthesis of Chondroitin Sulfate

1969 • 49 citations

The order of the CNBr peptides from the α1 chain of collagen

1969 • 47 citations

THE IDENTIFICATION OF A SULFATED MUCOPOLYSACCHARIDE IN CHICK EMBRYOS, STAGES 11-23

1963 • 47 citations

Polysaccharides

1966 • 46 citations

Solubility of Collagen Fibrils formed in vitro in the Presence of Sulphated Acid Mucopolysaccharide-protein

1969 • 45 citations

The synthesis of collagen during the development of Xenopus laevis

1968 • 44 citations

THE OCCURRENCE OF INTRACELLULAR CHONDROITIN SULFATE

1963 • 42 citations

Autoradiographic Studies with S35-Sulfate

1958 • 40 citations

Metabolism in vivo of connective-tissue mucopolysaccharides

1963 • 36 citations

Intercellular connective tissue fibrils in the notochordal epithelium of the early chick embryo

1973 • 35 citations

The order of the CNBr peptides from the α2 chain of collagen

1970 • 34 citations

Differences between CNBr peptides of soluble and insoluble bovine collagens

1971 • 34 citations

Collagen Molecules: Distribution of Alpha Chains

1970 • 33 citations

Determination of the Molecular Weight Distribution of Chondroitin Sulfate B by Sedimentation Equilibrium

1964 • 32 citations

Homologous regions of collagen α1(I) and α1(II) chains: Apparent clustering of variable and invariant amino acid residues

1974 • 32 citations

The collagen of osteogenic cartilage in the embryonic chick

1973 • 31 citations

The isolation and amino acid composition of the α chains of chicken-bone collagen

1967 • 29 citations

Protein–polysaccharide of chicken cartilage and chondrocyte cell cultures

1970 • 26 citations

Periodic fibrillar material in membrane-bound bodies in notochordal epithelium of the early chick embryo

1973 • 25 citations

Renaturation and ordering by electron microscopy of the cyanogen bromide peptides from the α2 chain of chick skin collagen

1970 • 23 citations

Newer Knowledge of Chondrogenesis

1973 • 22 citations

The Inhibition of the Maturation of Newly Synthesized Bone Collagen by -Aminopropionitrile in Tissue Culture

1968 • 22 citations

The solubilization of collagen and protein–polysaccharides from the developing cartilage of lathyrytic chicks

1969 • 20 citations

Fractionation of the α- and β-chains of collagen by Sephadex gel filtration

1965 • 20 citations

A histochemical study of sulphated glycosaminoglycans associated with the somites of the chick embryo

1973 • 18 citations

The Localization and Potential Function of Glycosyltransferases in Chick Embryos

1973 • 18 citations

Differences in glycosaminoglycans derived from chick embryo chondrocytes grown in vitro and in vivo

1964 • 16 citations

Collagen synthesis in frog embryo endoderm cells

1971 • 11 citations

A versatile chamber for the growth of duplicate monolayer cell cultures directly on microscope slides

1969 • 3 citations

Meeting Report

1975 • 1 citations