Inducers and Inhibitors of Leukemic Cell Differentiation in Culture

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,865 citations

Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome

1975 • 2,228 citations

Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture

1977 • 2,134 citations

Induction of differentiation of the human promyelocytic leukemia cell line (HL-60) by retinoic acid.

1980 • 1,997 citations

Terminal differentiation of human promyelocytic leukemia cells induced by dimethyl sulfoxide and other polar compounds.

1978 • 1,624 citations

Hemoglobin Synthesis in Murine Virus-Induced Leukemic Cells In Vitro: Stimulation of Erythroid Differentiation by Dimethyl Sulfoxide

1971 • 1,371 citations

Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

1979 • 1,019 citations

Characterization of the continuous, differentiating myeloid cell line (HL-60) from a patient with acute promyelocytic leukemia

1979 • 905 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Erythroleukemic Differentiation

1978 • 694 citations

Butyric acid, a potent inducer of erythroid differentiation in cultured erythroleukemic cells

1975 • 663 citations

Induction of Differentiation in Human Promyelocytic Leukemia Cells by Tumor Promoters

1979 • 594 citations

Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia

1978 • 593 citations

K562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin

1979 • 532 citations

Differentiation of a cell line of myeloid leukemia

1969 • 520 citations

Induction of terminal differentiation in human promyelocytic leukemia cells by tumor-promoting agents.

1979 • 513 citations

Induction of erythroid differentiation in the human leukaemia cell line K562

1979 • 470 citations

K562—A human erythroleukemic cell line

1979 • 463 citations

Differentiation of normal and neoplastic hematopoietic cells

1978 • 394 citations

A new group of potent inducers of differentiation in murine erythroleukemia cells.

1976 • 379 citations

Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis

1976 • 374 citations

Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion

1979 • 337 citations

Chronic Myelocytic Leukemia

1978 • 332 citations

The Distribution of the Philadelphia Chromosome in Patients with Chronic Myelogenous Leukemia

1963 • 294 citations

Tumor promoters inhibit spontaneous and induced differentiation of murine erythroleukemia cells in culture.

1977 • 238 citations

5-Bromodeoxyuridine: Effect on Myogenesis in vitro

1964 • 231 citations

Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells

1976 • 228 citations

Induction of erythroid differentiation in murine virus infected eythroleukemia cells by highly polar compounds.

1975 • 220 citations

Hematopoietic Stem Cells

1979 • 212 citations

Correlation between Hypomethylation of DNA and Expression of Globin Genes in Friend Erythroleukemia Cells

1977 • 209 citations

Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture.

1977 • 207 citations

Effect of hexamethylene bisacetamide on the commitment to differentiation of murine erythroleukemia cells.

1977 • 193 citations

Different Blocks in the Differentiation of Myeloid Leukemic Cells

1974 • 191 citations

Induction of erythroid differentiation in vitro by purines and purine analogues

1976 • 186 citations

Breakage of DNA and alterations in folded genomes by inducers of differentiation in Friend erythroleukemic cells.

1978 • 173 citations

Suppression of Malignancy and Differentiation in Melanotic Melanoma Cells

1970 • 167 citations

Induction by ouabain of hemoglobin synthesis in cultured friend erythroleukemic cells

1976 • 158 citations

Control of lysozyme induction in the differentiation of myeloid leukemic cells

1976 • 148 citations

Normal Differentiation of Myeloid Leukaemic Cells induced by a Differentiation-inducing Protein

1972 • 138 citations

Induction of specific changes in the surface membrane of myeloid leukemic cells by steroid hormones

1975 • 132 citations

Changes in DNA associated with induction of erythroid differentiation by dimethyl sulfoxide in murine erythroleukemia cells.

1978 • 132 citations

Differentiation of human leukemias in response to 12-0- tetradecanoylphorbol-13-acetate in vitro

1980 • 121 citations

Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells.

1977 • 118 citations

Hemoglobin Biosynthesis in Murine Virus-induced Leukemic Cells In Vitro: Structure and Amounts of Globin Chains Produced

1972 • 117 citations

Terminal differentiation in human promyelocytic leukaemic cells in the absence of DNA synthesis

1980 • 115 citations

Erythroid cell differentiation: murine erythroleukemia cell variant with unique pattern of induction by polar compounds.

1976 • 111 citations

Opposing effects of tumour promoters on erythroid differentiation

1978 • 110 citations

Hemoglobin synthesis in murine virus-induced leukemic cells in vitro. III. Effects of 5-bromo-2?-deoxyuridine, dimethylformamide and dimethylsulfoxide

1973 • 110 citations

Differentiation of Erythroleukemic Cells in the Presence of Inhibitors of DNA Synthesis

1975 • 104 citations

Induction of erythroid differentiation by dimethylsulfoxide in cells infected with Friend virus: relationship to the cell cycle.

1975 • 104 citations

Induction of spectrin in erythroleukemic cells transformed by Friend virus.

1977 • 97 citations

Hematopoietic Stem Cells

1979 • 91 citations

Induction of erythroid differentiation of murine erythroleukemia cells by nicotinamide and related compounds.

1979 • 90 citations

Indirect induction of differentiation in myeloid leukemic cells by lipid A

1978 • 88 citations

Polyamine biosynthesis enzymes in the induction and inhibition of differentiation in Friend erythroleukemia cells.

1980 • 81 citations

Regulation of Hemoglobin Synthesis in a Murine Erythroblastic Leukemic Cell: The Requirement for Replication to Induce Hemoglobin Synthesis

1974 • 77 citations

Erythroid differentiation in cultured Friend leukemia cells treated with metabolic inhibitors.

1976 • 77 citations

Inducers of erythroleukemic differentiation. Relationship of structure to activity among planar-polar compounds.

1978 • 76 citations

Control of globin gene expression by steroid hormones in differentiating friend leukemia cells

1978 • 76 citations

Effects of 5-Bromo-2′-Deoxyuridine on Production of Globin Messenger RNA in Dimethyl Sulfoxide-Stimulated Friend Leukemia Cells

1973 • 74 citations

Biochemistry of cell differentiation II

1977 • 73 citations

Increase in globin chains and globin mRNA in erythroleukemia cells in response to hemin

1977 • 72 citations

Prolongation of survival time of mice inoculated with myeloid leukemia cells by inducers of normal differentiation.

1979 • 72 citations

Hematopoietic Stem Cells

1979 • 72 citations

Tissue Culture Studies on Murine Virus-induced Leukemia Cells: Isolation of Single Cells in Agar-Liquid Medium

1967 • 70 citations

Inhibition of dimethyl sulfoxide-stimulated Friend cell erythrodifferentiation by hydrocortisone and other steroids.

1978 • 70 citations

Tumor promoter-mediated inhibition of cell differentiation: suppression of the expression of erythroid functions in murine erythroleukemia cells.

1979 • 63 citations

Inhibition of transcription and translation of globin messenger RNA in dimethyl sulfoxide-stimulated Friend erythroleukemic cells treated with interferon.

1977 • 58 citations

Differentiation of erythroleukemia cells in vitro: properties of chemical inducers

1975 • 58 citations

Induction of murine erythroleukemia differentiation by actinomycin D

1978 • 58 citations

Significance of the cell cycle in commitment of murine erythroleukemia cells to erythroid differentiation

1978 • 56 citations

The effect of tumor-promoting phorbol diesters on terminal differentiation of cells in culture

1980 • 55 citations

Controlling the production of blood cells

1979 • 52 citations

Interferon inhibits dimethyl sulphoxide-induced erythroid differentiation of Friend leukaemia cells

1977 • 52 citations

Cryoprotective agents as inducers of erythroleukemic cell differentiation in vitro

1976 • 52 citations

Differentiation and Neoplasia

1980 • 50 citations

Effect of interferon on growth and division cycle of Friend erythroleukemic murine cells in vitro.

1977 • 50 citations

Induction of differentiation of human and murine myeloid leukemia cells in culture by tunicamycin.

1980 • 46 citations

Inhibition by dexamethasone of commitment to erythroid differentiation in murine erythroleukemia cells.

1979 • 46 citations

Analysis of erythroid differentiation in friend cells using noninducible variants

1978 • 42 citations

Haemoglobin synthesis in inducible, uninducible and hybrid friend cell clones

1974 • 42 citations

Synthesis of globin mRNA in relation to the cell cycle during induced murine erythroleukemia differentiation.

1978 • 40 citations

Glucocorticoid binding and mechanism of resistance in some clones of mouse myeloid leukemic cells resistant to induction of differentiation by dexamethasone

1977 • 40 citations

Isolation and characterization of high and low differentiation-inducible Friend leukemia lines.

1976 • 40 citations

Differentiation of erythroleukemic cells in vitro: Irreversible induction by dimethyl sulfoxide (DMSO)

1975 • 39 citations

Control of normal differentiation of myeloid leukemic cells. VI. Inhibition of cell multiplication and the formation of macrophages

1975 • 37 citations

DNA synthesis is not required for the commitment of murine erythroleukemia cells

1980 • 37 citations

The phenotypes of variant clones of Friend mouse erythroleukemic cells resistant to dimethyl sulfoxide.

1976 • 36 citations

Differentiation of a cell line of mouse myeloid leukemia

1976 • 34 citations

ORIGIN OF SOME LYMPHOCYTES FROM LEUKEMIC STEM CELLS

1978 • 34 citations

Prostaglandin E1, an inducer of erythroid differentiation of friend erythroleukemia cells

1977 • 33 citations

Glucorticoid-induced differentiation of cultured mouse myeloid leukemia cells.

1977 • 31 citations

Use of resistant or hypersensitive variant clones of Friend cells in analysis of mode of action of inducers.

1978 • 30 citations

Differentiation of cultured Friend leukemia cells induced by short-chain fatty acids.

1975 • 30 citations

The dependence of erythroid differentiation on cell replication in dimethyl sulfoxide-treated friend leukemia-virus-infected cells

1976 • 22 citations

Actinomycin D restores in vivo sensitivity to differentiation induction of non‐differentiating mouse myeloid leukemia cells

1979 • 22 citations

Enhancement of Erythrocytic Maturation of Friend Virus-Induced Leukemia Cells in vitro1

2015 • 22 citations

Hydrocortisone inhibits DMSO — induced differentiation of friend erythroleukemia cells

1978 • 21 citations

Isolation and characterization of a subline of Friend erythroleukemia cells that differentiate in tissue culture in the absence of inducers.

1977 • 17 citations

Bromodeoxyuridine inhibition of Friend leukemia cell induction by butyric acid: Time course of inhibition, reversal, and effect of other base analogs

1976 • 17 citations

Phenotypic Variants of Differentiation-Inducible Friend Leukemia Lines: Isolation and Correlation between Inducibility and Virus Release

2015 • 16 citations

Induction of differentiation of murine erythroleukemia cells by aminonucleoside of puromycin and inhibition of this induction by purines and purine derivatives.

1980 • 15 citations

Clones of friend leukemia cells: Differences in karyotypes and responsiveness to inducers of differentiation

1976 • 15 citations

Induction of erythroid differentiation in friend leukemia cells by bromodeoxyuridine

1978 • 15 citations

Induction of erythroid differentiation in friend murine erythroleukemic cells by inorganic selenium compounds

1979 • 14 citations

Growth in high-K+ medium induces friend cell differentiation

1979 • 14 citations

Inducers of Friend leukaemic cell differentiation in vitro–effects of in vivo administration

1976 • 12 citations

Erythroid cell differentiation

1978 • 11 citations

Induction by synthetic polyribonucleotide poly(I) of differentiation of cultured mouse myeloid leukemic cells

1978 • 11 citations

New human myeloid leukaemia cell line undergoes red shift

1979 • 10 citations

Differentiation of a resistant clone of mouse myeloid leukemia cells with dimethyl sulfoxide and ascitic fluid.

1977 • 9 citations

Regulatory Interactions in Normal and Leukemic Myelopoiesis

1979 • 5 citations

Regulation of Erythroid Differentiation: Characterization of Rauscher and Friend Virus-Transformed Proerythroid Cells

1979 • 1 citations