Studies on the mechanism of ethanol-induced gastric damage in rats

Cytoprotection by prostaglandins in rats

1979 • 1,698 citations

MAST CELLS IN RAT GASTROINTESTINAL MUCOSA

1966 • 561 citations

Mild irritants prevent gastric necrosis through "adaptive cytoprotection" mediated by prostaglandins

1983 • 492 citations

Early Vascular Injury and Increased Vascular Permeability in Gastric Mucosal Injury Caused by Ethanol in the Rat

1985 • 478 citations

MAST CELLS IN RAT GASTROINTESTINAL MUCOSA

1966 • 474 citations

Microscopic Analysis of Ethanol Damage to Rat Gastric Mucosa After Treatment With a Prostaglandin

1982 • 382 citations

Experiments AND Observations ON THE Gastric Juice AND THE Physiology OF Digestion.

1929 • 349 citations

Histologic and Microcirculatory Changes in Alcohol-Induced Gastric Lesions in the Rat: Effect of Prostaglandin Cytoprotection

1984 • 326 citations

Formation and actions of leukotrienes

1984 • 320 citations

GASTRITIS

1954 • 223 citations

Ethanol stimulates formation of leukotriene C4 in rat gastric mucosa

1986 • 222 citations

Ethanol Damage to Canine Oxyntic Glandular Mucosa.

1967 • 205 citations

ART. XIII. Experiments and Observations on the Gastric Juice, and the Physiology of Digestion

1834 • 177 citations

Concomitant histochemical demonstration of histamine and catecholamines in enterochromaffin-like cells of gastric mucosa

1967 • 176 citations

Cholinergic-mediated gastric mast cell degranulation with subsequent histamine H1- and H2-receptor activation in stress ulceration in rats

1979 • 163 citations

Early microcirculatory stasis in acute gastric mucosal injury in the rat and prevention by 16,16-dimethyl prostaglandin E2 or sodium thiosulfate

1986 • 159 citations

Experiments and Observations on the Gastric Juice and the Physiology of Digestion

1961 • 132 citations

Microvascular and vascular smooth muscle actions of ethanol, acetaldehyde, and acetate.

1982 • 131 citations

Reduction by cytoprotective agents of ethanol-induced damage to the rat gastric mucosa: a correlated morphological and physiological study

1982 • 125 citations

Gastric vasoconstrictor actions of leukotriene C4, PGF2 alpha, and thromboxane mimetic U-46619 on rat submucosal microcirculation in vivo

1985 • 116 citations

The Inflammatory Reaction

1986 • 100 citations

The inflammatory reaction

1985 • 96 citations

Changes in the Fine Structure of Mouse Gastric Epithelium Produced by Ethanol and Urea

1974 • 96 citations

Prostaglandin cytoprotection against ethanol-induced gastric injury in the rat

1985 • 92 citations

Role of gastric mucosal folds in formation of focal ulcers in the rat.

1982 • 86 citations

Role of prostanoids in the protective actions of BW755C on the gastric mucosa

1985 • 77 citations

Role of glutathione in gastric mucosal cytoprotection

1984 • 75 citations

Inhibition of the A-23187-stimulated leukotriene and prostaglandin biosynthesis of rat basophil leukemia (RBL-1) cells by nonsteroidal anti-inflammatory drugs, antioxidants, and calcium channel blockers

1983 • 68 citations

In vivo microscopy of the gastric microcirculation

1972 • 66 citations

Effects of Ethanol on Terminal Arterioles and Muscular Venules

1979 • 66 citations

Arachidonic acid metabolism in glutathione-deficient macrophages.

1982 • 64 citations

Effect of Prostaglandin E₂, Cimetidine, and Atropine on Ethanol-Induced Gastric Mucosal Damage in the Rat

1980 • 55 citations

A study of the vascular and acid‐secretory responses of the rat gastric mucosa to histamine.

1976 • 55 citations

Ultrastructural changes of the canine gastric mucosa after topical application of graded concentrations of ethanol

1976 • 53 citations

Effects of Alcohol on Gastric Mucosa

1956 • 50 citations

Role of prostaglandin and thromboxane biosynthesis in gastric necrosis produced by taurocholate and ethanol

1983 • 49 citations

A Method for the Assay of ‘Slow Reacting Substance’.

1959 • 48 citations

Arachidonic acid protection of gastric mucosa against alcohol injury: sequential analysis of morphologic and functional changes.

1983 • 43 citations

Gastric Cytoprotection

1985 • 42 citations

Ethanol and Contraction of Venous Smooth Muscle

1976 • 40 citations

Effects of Zinc Sulphate on Ethanol- and Indomethacin-Induced Ulceration and Changes in Prostaglandin E<sub>2</sub> and Histamine Levels in the Rat Gastric Glandular Mucosa

1985 • 40 citations

Role of ethanol metabolism in the ethanol-induced increase in splanchnic circulation

1986 • 39 citations

H1 and H2 histamine receptors in rat gastric submucosal arterioles

1980 • 25 citations

Effect of increased gastric mucosal histamine on alcohol-induced gastric damage in rats

1982 • 25 citations

Changes in mucosal and venous histamine concentrations during instillation of ethanol in the canine stomach

1976 • 21 citations

RESPONSES OF RABBIT PORTAL VEIN TO HISTAMINE

1978 • 15 citations

Effects of somatostatin on ethanol-induced gastric erosions in the rat: Role of mast cells

1986 • 10 citations

Positive interaction between leukotriene C4 and histamine and other mediators on vascular tissues

1985 • 9 citations

Combined ulcerogenic effect of ethanol and acetylsalicylic acid on the gastric mucosa of the rat

1983 • 2 citations