[2] Transition state analogs as potential affinity labeling regents

Analog approaches to the structure of the transition state in enzyme reactions

1972 • 599 citations

P1,P5-Di(adenosine-5′)pentaphosphate, a Potent Multisubstrate Inhibitor of Adenylate Kinase

1973 • 524 citations

Enzymatic Catalysis and Transition-State Theory

1973 • 501 citations

Transition States of Biochemical Processes

1978 • 418 citations

TRANSITION STATE ANALOG INHIBITORS AND ENZYME CATALYSIS

1976 • 415 citations

Transition State Analogues for Enzyme Catalysis

1969 • 381 citations

Lactic Dehydrogenase

1959 • 258 citations

X-ray crystallographic study of boronic acid adducts with subtilisin BPN' (Novo). A model for the catalytic transition state.

1975 • 218 citations

Inhibition of glutamine synthetase by methionine sulfoximine. Studies On Methionine sulfoximine phosphate

1969 • 158 citations

2-Phenylethaneboronic acid, a possible transition-state analog for chymotrypsin

1971 • 144 citations

Selective Inhibition of Aminoacyl Ribonucleic Acid Synthetases by Aminoalkyl Adenylates^*

1967 • 119 citations

Tetrose Diphosphate, a Specific Inhibitor of Glyceraldehyde 3-Phosphate Dehydrogenase

1959 • 99 citations

An Activated Intermediate Analogue

1974 • 86 citations

Slow binding of D-galactal, a reversible inhibitor of bacterial β-galactosidase

1974 • 82 citations

Influence of pH on the interaction of inhibitors with triosephosphate isomerase and determination of the pKa of the active-site carboxyl group

1975 • 70 citations

Inhibition of β-D-galactosidases by D-galactal

1969 • 65 citations

Binding of peptides to elastase. Implications for the mechanism of substrate hydrolysis

1974 • 47 citations

Tetrahydrodeoxyuridylate: A potent inhibitor of deoxycytidylate deaminase

1971 • 43 citations

New, specific and reversible bifunctional alkylborinic acid inhibitor of acetylcholinesterase

1974 • 35 citations

Kinetics of inhibition of Aeromonas aminopeptidase by leucine methyl ketone derivatives

1974 • 23 citations

d-Threose 2,4-Diphosphate Inhibition of d-Glyceraldehyde 3-Phosphate Dehydrogenase

1959 • 20 citations

Tetrahedral Intermediate in a Specific α-Chymotrypsin Inhibitor Complex Detected by Laser Raman Spectroscopy

1975 • 16 citations