T cells from patients with Hodgkin's disease have a defective T-cell receptor zeta chain expression that is reversible by T-cell stimulation with CD3 and CD28

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Partial T cell signaling: Altered phospho-? and lack of zap70 recruitment in APL-induced T cell anergy

1994 • 608 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

Impaired in Vitro Lymphocyte Transformation in Hodgkin's Disease

1965 • 379 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: Expression of interleukin‐10 in interferon‐γ and in interleukin‐4‐expressing cells

1994 • 305 citations

Signals through T cell receptor-zeta chain alone are insufficient to prime resting T lymphocytes.

1995 • 266 citations

Binding of Sheep Erythrocytes to Human Lymphocytes

1972 • 264 citations

Hodgkin's disease. An immunodepleting and immunosuppressive disorder.

1975 • 215 citations

Hodgkin's disease: Establishment and characterization of four in vitro cell lines

1981 • 162 citations

Cure of Xenografted Human Tumors by Bispecific Monoclonal Antibodies and Human T Cells

1994 • 161 citations

Studies of Cell Subpopulations Mediating Mitogen Hyporesponsiveness in Patients with Hodgkin's Disease

1978 • 90 citations

Homologous and Heterologous Skin Transplantation in Patients With Lymphomatous Disease

1961 • 86 citations

Lymphoid subpopulations of peripheral blood and spleen in untreated Hodgkin's disease

1981 • 62 citations

Tumor Therapy by Immune Recruitment with Bispecific Antibodies

1995 • 58 citations

The role of lymphocyte subsets and adhesion molecules in T cell‐dependent cytotoxicity mediated by CD3 and CD28 bispecific monoclonal antibodies

1995 • 47 citations

The genetic modification of T cells for cancer therapy: an overview of laboratory and clinical trials.

1994 • 42 citations

Depletion of Thymus Dependent Lymphocytes in Hodgkin's Disease

1974 • 38 citations

Decrease in 5'-nucleotidase activity in malignant transformed and normal stimulated cells.

1978 • 36 citations

Cure of disseminated xenografted human Hodgkin's tumors by bispecific monoclonal antibodies and human T cells: the role of human T-cell subsets in a preclinical model

1996 • 35 citations

Distribution of T-lymphocyte subsets in Hodgkin's disease characterized by monoclonal antibodies

1982 • 34 citations

Correlation between disease activity and T‐cell CD3 chain expression in a B‐cell lymphoma

1994 • 33 citations

Survival in Hodgkin's disease: the role of immunocompetence and other major risk factors

1982 • 25 citations

Defect in lectin-induce interleukin 2 (IL-2) production by peripheral blood lymphocytes of patients with Hodgkin's Disease

1985 • 23 citations

Reactivity of lymphocytes from primary neoplasms of lymphoid tissues

1976 • 20 citations

Decreased adenosine deaminase (ADA) and 5′nucleotidase (5NT) activity in peripheral blood T cells in hodgkin disease

1986 • 16 citations