Measurement of oxidative DNA damage by gas chromatography–mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases

Oxidants, antioxidants, and the degenerative diseases of aging.

1993 • 6,011 citations

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

1996 • 2,327 citations

Oxidative DNA Damage in the Parkinsonian Brain: An Apparent Selective Increase in 8‐Hydroxyguanine Levels in Substantia Nigra

1997 • 822 citations

The role of 8-hydroxyguanine in carcinogenesis

1990 • 732 citations

Commentary Oxidative Stress, Nutrition and Health. Experimental Strategies for Optimization of Nutritional Antioxidant Intake in Humans

1996 • 584 citations

Iron Ion-dependent Modification of Bases in DNA by the Superoxide Radical-generating System Hypoxanthine/Xanthine Oxidase

1989 • 363 citations

Assays for 8-hydroxy-2′-deoxyguanosine: A biomarker of in vivo oxidative DNA damage

1991 • 363 citations

Formation of 8-hydroxy(deoxy)guanosine and generation of strand breaks at guanine residues in DNA by singlet oxygen

1991 • 304 citations

Commentary the Measurement of Oxidative Damage to DNA by HPLC and GC/MS Techniques

1992 • 242 citations

Determination of 8-Oxoguanine in DNA by Gas Chromatography-Mass Spectrometry and HPLC-Electrochemical Detection: Overestimation of the Background Level of the Oxidized Base by the Gas Chromatography-Mass Spectrometry Assay

1995 • 204 citations

Endogenous carcinogenesis: molecular oncology into the twenty-first century--presidential address.

1989 • 189 citations

Hypochlorous Acid-Induced Base Modifications in Isolated Calf Thymus DNA

1997 • 161 citations

Characterization of free radical-induced base damage in DNA at biologically relevant levels

1986 • 160 citations

Base Modification and Strand Breakage in Isolated Calf Thymus DNA and in DNA from Human Skin Epidermal Keratinocytes Exposed to Peroxynitrite or 3-Morpholinosydnonimine

1996 • 156 citations

Quantitative determination of oxidative base damage in DNA by stable isotope‐dilution mass spectrometry

1993 • 153 citations

Measurement of oxidized and methylated DNA bases by HPLC with electrochemical detection

1996 • 141 citations

Observation and prevention of an artefactual formation of oxidized DNA bases and nucleosides in the GC-EMS method

1996 • 123 citations

Formation of cytosine glycol and 5,6-dihydroxycytosine in deoxyribonucleic acid on treatment with osmium tetroxide

1986 • 113 citations

What Structural Features Determine Repair Enzyme Specificity and Mechanism in Chemically Modified DNA?

1997 • 109 citations

Chemical nature of DNA-protein cross-links produced in mammalian chromatin by hydrogen peroxide in the presence of iron or copper ions

1991 • 99 citations

Quantitative Determination of 8-Hydroxyguanine and Guanine by Isotope Dilution Mass Spectrometry

1995 • 98 citations

[46] Gas chromatography—mass spectrometry of free radical-induced products of pyrimidines and purines in DNA

1990 • 52 citations