In vitro and in vivo transport of zidovudine (AZT) across the blood-brain barrier and the effect of transport inhibitors.

The Brain in AIDS: Central Nervous System HIV-1 Infection and AIDS Dementia Complex

1988 • 1,244 citations

Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): Experience at UCSF and review of the literature

1985 • 1,119 citations

Microdialysis—Theory and application

1990 • 651 citations

Handbook of toxic and hazardous chemicals and carcinogens

1986 • 596 citations

Early penetration of the blood-brain-barrier by HIV.

1988 • 444 citations

Clinical Pharmacology of 3'-Azido-2',3'-Dideoxythymidine (Zidovudine) and Related Dideoxynucleosides

1989 • 356 citations

Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism.

1986 • 246 citations

Independent blood-brain barrier transport systems for nucleic acid precursors

1975 • 238 citations

Declining incidence of AIDS dementia complex after introduction of zidovudine treatment.

1989 • 235 citations

Characterization of an "in vitro" blood-brain barrier: effects of molecular size and lipophilicity on cerebrovascular endothelial transport rates of drugs.

1988 • 139 citations

Measurement of albumin permeability across endothelial monolayers in vitro

1987 • 114 citations

Restricted Transport of 3'-Azido-3'-Deoxythymidine and Dideoxynucleosides Through the Blood-Brain Barrier

1988 • 101 citations

A rapid and simple cannulation technique for repeated sampling of cerebrospinal fluid in freely moving rats

1979 • 94 citations

The effects of salicylate and probenecid on the cerebrospinal fluid transport of penicillin, aminosalicyclic acid and iodide.

1974 • 88 citations

Probenecid inhibits the metabolic and renal clearances of zidovudine (AZT) in human volunteers.

1990 • 72 citations

Effect of Probenecid on the Renal and Nonrenal Clearances of Zidovudine and Its Distribution into Cerebrospinal Fluid in the Rabbit

1989 • 71 citations

Anti-retroviral therapy of AIDS and related disorders: General principles and specific development of dideoxynucleosides

1989 • 50 citations

Localization and Mechanism of Thymidine Transport in the Central Nervous System

1982 • 48 citations

Initial Clinical Experience with Dideoxynucleosides as Single Agents and in Combination Therapy

1990 • 42 citations

Tissue distribution and metabolic disposition of zidovudine in rats.

1990 • 42 citations

Brain and cerebrospinal fluid uptake of zidovudine (AZT) in rats after intravenous injection

1990 • 42 citations

Modeling the enhanced uptake of zidovudine (AZT) into cerebrospinal fluid. 1. Effect of probenecid.

1990 • 41 citations

Thymidine Transport in the Central Nervous System

1980 • 39 citations

The unit impulse response procedure for the pharmacokinetic evaluation of drug entry into the central nervous system

1989 • 37 citations

Transport of imipenem, a novel carbapenem antibiotic, in the rat central nervous system.

1989 • 34 citations

Drug Transport in the Central Nervous System: Role of Carriers

1990 • 33 citations

Zidovudine (Retrovir) update.

1990 • 24 citations

State of antiretroviral therapy with zidovudine

1989 • 24 citations

Specific routine determination of 3'-azido-3'-deoxythymidine (AZT) in plasma by partly automated liquid chromatography.

1989 • 21 citations

Central nervous system involvement in human immunodeficiency virus disease. A prospective study including neurological examination, computerized tomography, and magnetic resonance imaging.

1991 • 15 citations