Vascular Endothelial Barrier Function and Its Regulation

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

Thermodynamic analysis of the permeability of biological membranes to non-electrolytes

1958 • 2,157 citations

On the Absorption of Fluids from the Connective Tissue Spaces

1896 • 2,075 citations

STUDIES ON INFLAMMATION

1961 • 1,539 citations

Handbook of Physiology—The Cardiovascular System

1985 • 1,128 citations

Transferrin receptor on endothelium of brain capillaries

1984 • 1,008 citations

Filtration, Diffusion and Molecular Sieving Through Peripheral Capillary Membranes

1951 • 972 citations

Capillary endothelial cell cultures: phenotypic modulation by matrix components.

1983 • 611 citations

Nonmuscle Actin-Binding Proteins

1985 • 589 citations

Control of microtubule assembly-disassembly by calcium-dependent regulator protein.

1978 • 493 citations

Receptor-Mediated Transport of Insulin Across Endothelial Cells

1985 • 462 citations

Effects of unstirred layers on membrane phenomena.

1984 • 451 citations

A fiber matrix model of capillary permeability

1980 • 392 citations

The plasma proteins : structure, function, and genetic control

1975 • 388 citations

Specific binding sites for albumin restricted to plasmalemmal vesicles of continuous capillary endothelium: receptor-mediated transcytosis.

1986 • 375 citations

Passage of dextran molecules across the blood-lymph barrier.

1956 • 354 citations

Phosphorylation of microtubule-associated proteins regulates their interaction with actin filaments.

1983 • 319 citations

Multiple pathways of capillary permeability.

1977 • 313 citations

Role of endothelial cell cytoskeleton in control of endothelial permeability.

1982 • 310 citations

Thrombin‐induced increase in albumin permeability across the endothelium

1986 • 307 citations

A tumor promoter induces rapid and coordinated reorganization of actin and vinculin in cultured cells.

1984 • 303 citations

Histamine type I receptor occupancy increases endothelial cytosolic calcium, reduces F-actin, and promotes albumin diffusion across cultured endothelial monolayers.

1986 • 289 citations

Correlation between thrombin-induced prostacyclin production and inositol trisphosphate and cytosolic free calcium levels in cultured human endothelial cells.

1987 • 281 citations

Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase.

1988 • 279 citations

Estimation of equivalent pore radii of pulmonary capillary and alveolar membranes

1970 • 278 citations

Increased endothelial albumin permeability mediated by protein kinase C activation.

1990 • 271 citations

Transcytosis of albumin in capillary endothelium.

1987 • 269 citations

Differentiated microdomains on the luminal surface of the capillary endothelium. I. Preferential distribution of anionic sites.

1981 • 267 citations

Functional heterogeneity of vascular endothelial cells

1987 • 265 citations

Molecular sieving characteristics of the cultured endothelial monolayer

1987 • 254 citations

Role of cyclic adenosine monophosphate in the induction of endothelial barrier properties

1989 • 251 citations

Vinculin, a cytoskeletal substrate of protein kinase C.

1983 • 215 citations

Reversible oxidant-induced increases in albumin transfer across cultured endothelium: alterations in cell shape and calcium homeostasis

1985 • 210 citations

Serum Albumin

1975 • 208 citations

Clearance of Thrombin from Circulation in Rabbits by High-affinity Binding Sites on Endothelium

1980 • 204 citations

Expression of organ-specific antigens on capillary endothelial cells

1985 • 200 citations

Binding of human thrombin to cultured human endothelial cells.

1979 • 193 citations

Tumor promoter-induced changes in the permeability of epithelial cell tight junctions

1981 • 185 citations

Permeability characteristics of cultured endothelial cell monolayers

1988 • 185 citations

Contribution of actin to the structure of the cytoplasmic matrix.

1984 • 172 citations

How do inositol phosphates regulate calcium signaling?

1989 • 171 citations

Differentiated microdomains on the luminal surface of capillary endothelium: distribution of lectin receptors.

1982 • 166 citations

Effects of tumor promoters on LLC-PK1 renal epithelial tight junctions and transepithelial fluxes

1986 • 163 citations

Handbook of Physiology. Circulation. Vol. III, Sec. 2 W. F. Hamilton P. Dow

1966 • 158 citations

Differential expression of cell surface glycoproteins on various organ‐derived microvascular endothelia and endothelial cell cultures

1988 • 155 citations

Redistribution of surface anionic sites on the luminal front of blood vessel endothelium after interaction with polycationic ligand.

1976 • 147 citations

Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein.

1988 • 146 citations

Interstitial diffusion of macromolecules in the rat mesentery

1979 • 144 citations

Capillary transport of macromolecules: pores and other endothelial pathways

1985 • 136 citations

Permeability of human endothelial monolayers: effect of vasoactive agonists and cAMP

1989 • 128 citations

The Endothelial Cells of Large and Small Blood Vessels

1981 • 126 citations

Calculation of unstirred layer thickness in membrane transport experiments: a survey

1983 • 120 citations

Ca2+ regulation of tight-junction permeability and structure in Necturus gallbladder

1983 • 118 citations

Identification of albumin-binding proteins in capillary endothelial cells.

1988 • 118 citations

Measurement of albumin permeability across endothelial monolayers in vitro

1987 • 114 citations

Increased permeability of microcarrier-cultured endothelial monolayers in response to histamine and thrombin. A model for the in vitro study of increased vasopermeability.

1986 • 113 citations

Diacylglycerol inhibits gap junctional communication in cultured epidermal cells: Evidence for a role of protein kinase C

1985 • 111 citations

Microvascular endothelial cell heterogeneity: Interactions with leukocytes and tumor cells

1990 • 104 citations

Specific albumin binding to microvascular endothelium in culture

1988 • 103 citations

The effects of isoproterenol on intracellular calcium concentration.

1988 • 102 citations

The effects of native and modified bovine serum albumin on the permeability of frog mesenteric capillaries.

1985 • 90 citations

Nature of Thrombin-induced Sustained Increase in Cytosolic Calcium Concentration in Cultured Endothelial Cells

1989 • 85 citations

Histamine and inositol phosphate accumulation in endothelium: cAMP and a G protein

1989 • 83 citations

Endothelial Albumin Binding Proteins Are Membrane-associated Components Exposed on the Cell Surface

1989 • 83 citations

Adenylate cyclase and protein kinase C mediate opposite actions on endothelial junctions

1990 • 81 citations

Phallacidin prevents thrombin-induced increases in endothelial permeability to albumin

1989 • 80 citations

Isoproterenol reduces thrombin-induced pulmonary endothelial permeability in vitro

1989 • 76 citations

CALCIUM AND THE CYTOSKELETON

1986 • 74 citations

Calcium dependence of the thrombin-induced increase in endothelial albumin permeability

1989 • 72 citations

Anionized and cationized hemeundecapeptides as probes for cell surface charge and permeability studies: differentiated labeling of endothelial plasmalemmal vesicles.

1985 • 70 citations

Serotonin, norepinephrine, and histamine mediation of endothelial cell barrier function in vitro

1986 • 69 citations

Endothelial monolayer permeability to macromolecules.

1987 • 68 citations

Monohydroxyeicosatetraenoic acids (5-HETE and 15-HETE) induce pulmonary vasoconstriction and edema.

1988 • 65 citations

ENDOTHELIAL SURFACE CHARGE AND ITS POSSIBLE RELATIONSHIP TO THROMBOGENESIS

1976 • 62 citations

Culture and characterization of pulmonary microvascular endothelial cells

1992 • 60 citations

Distribution and movement of anionic cell surface sites in cultured human vascular endothelial cells

1979 • 60 citations

Measurement of cytoplasmic calcium in single microvessels with increased permeability

1990 • 60 citations

Differentiated micro domains on the luminal surface of the capillary endothelium

1981 • 58 citations

Cytoskeletal reorganizations responsible for the phorbol ester-induced formation of cytoplasmic processes: possible involvement of intermediate filaments.

1990 • 57 citations

Influence of vasoactive agents on cytoplasmic free calcium in vascular endothelial cells

1988 • 55 citations

The effect of ethchlorvynol on cultured endothelial cells. A model for the study of the mechanism of increased vascular permeability.

1985 • 48 citations

Chemotactic factors induced vimentin phosphorylation in rabbit peritoneal neutrophil.

1984 • 46 citations

Lectin analysis of common glycoproteins detected on the surface of continuous microvascular endothelium in situ and in culture: identification of sialoglycoproteins.

1990 • 45 citations

Diacylglycerols and PMA induce actin polymerization and distinct shape changes in lymphocytes: relation to fluid pinocytosis and locomotion

1989 • 44 citations

Synthesis and distribution of cytoskeletal elements in endothelial cells as a function of cell growth and organization

1982 • 43 citations

Methods in laboratory investigation. Exclusion of trypan blue from microcarriers by endothelial cells: an in vitro barrier function test.

1984 • 41 citations

Active transendothelial transport of albumin. Interstitium to lumen.

1985 • 40 citations

Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic amp and reducing cytoplasmic free calcium mobilization

1987 • 40 citations

Lectin binding to gp60 decreases specific albumin binding and transport in pulmonary artery endothelial monolayers

1991 • 40 citations

Role of albumin arginyl sites in albumin‐induced reduction of endothelial hydraulic conductivity

1989 • 38 citations

Release of intracellular calcium by two different second messengers in airway epithelium

1989 • 38 citations

Propagation of electromagnetic waves of crossroads with a reflector inside a tunnel

1989 • 36 citations

Regulation of ion permeability in frog brain venules. Significance of calcium, cyclic nucleotides and protein kinase C.

1987 • 36 citations

ENDOTHELIAL CELL RECEPTORS FOR HISTAMINE*

1982 • 34 citations

Capillary permeability, extracellular space estimation, and lymph flow

1966 • 32 citations

Effects of alterations in endothelial cell volume on transendothelial albumin permeability

1987 • 32 citations

Reassessment of fluid‐phase endocytosis and diacytosis in monolayer cultures of human fibroblasts

1988 • 32 citations

Transport Pathways and Processes

1988 • 30 citations

Passage of uncharged dextrans from blood to lung lymph in awake sheep

1985 • 29 citations

Selectivity of the endothelial monolayer: Effects of increased permeability

1988 • 29 citations

Endothelial Cell-Extracellular Matrix Interactions

1988 • 27 citations

<b>IMMUNOCYTOCHEMICAL EVIDENCE FOR TRANSENDOTHELIAL TRANSPORT OF ALBUMIN AND FIBRINOGEN IN RAT HEART AND </b><b>DIAPHRAGM </b>

1983 • 24 citations

Effect of superfusate albumin on single capillary hydraulic conductivity

1987 • 24 citations

Macromolecule Transport across the Pulmonary Microvessel Walls

1985 • 21 citations

INTRACELLULAR CALCIUM RECEPTOR MECHANISMS

1986 • 21 citations

Direct staining and visualization of endothelial monolayers cultured on synthetic polycarbonate filters.

1988 • 21 citations

Core temperature regulation of heart rate during exercise in humans

1987 • 21 citations

Enzymatic activity is necessary for thrombin-mediated increase in endothelial permeability

1990 • 20 citations

Electrical conductivity and its use in estimating an equivalent pore size for arterial endothelium

1986 • 19 citations

Actin pools and actin microfilament organization in cultured human endothelial cells after exposure to thrombin

1984 • 19 citations

Transendothelial albumin flux: evidence against asymmetric transport

1986 • 18 citations

Interactive Effects of O₃, Cytochalasin D, and Vinblastine on Transepithelial Transport and Cytoskeleton in Rat Airways

1990 • 16 citations

Myosin light chain phosphorylation in fibroblast shape change, detachment and patching.

1986 • 14 citations

Molecular distribution within a 1% collagen gel column

1979 • 6 citations

CYCLIC NUCLEOTIDE PHOSPHODIESTERASE INHIBITORS PREVENT AGGREGATION AND SECRETION OF HUMAN PLATELETS BY RAISING CYCLIC AMP AND REDUCING CYTOPLASMIC FREE CALCIUM MOBILIZATION

1987 • 1 citations

PERMSELECTIVITY OF CULTURED ENDOTHELIAL MONOLAYERS: EFFECT OF SIZE AND CHARGE OF THE TRANSPORTED MOLECULES

1987 • 1 citations