Clozapine: Current Status and Role in the Pharmacotherapy of Schizophrenia

The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia

1987 • 19,723 citations

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

The Quality of Life Scale: An Instrument for Rating the Schizophrenic Deficit Syndrome

1984 • 1,671 citations

Risperidone in the treatment of schizophrenia

1994 • 1,205 citations

Clozapine-Induced Agranulocytosis -- Incidence and Risk Factors in the United States

1993 • 948 citations

A Canadian Multicenter Placebo-Controlled Study of Fixed Doses of Risperidone and Haloperidol in the Treatment of Chronic Schizophrenic Patients

1993 • 884 citations

Neuroleptics and the Natural Course of Schizophrenia

1991 • 777 citations

Clinical studies on the mechanism of action of clozapine: the dopamine-serotonin hypothesis of schizophrenia

1989 • 600 citations

Why Do Schizophrenic Patients Refuse to Take Their Drugs?

1974 • 584 citations

Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of Psychoses

1988 • 554 citations

Effects of Six Months of Clozapine Treatment on the Quality of Life of Chronic Schizophrenic Patients

1990 • 351 citations

Treatment of the Neuroleptic-Nonresponsive Schizophrenic Patient

1992 • 332 citations

Schizophrenia: Scientific progress

1990 • 330 citations

D1- and D2-dopamine receptor occupancy during treatment with conventional and atypical neuroleptics

1989 • 322 citations

Risperidone versus haloperidol in the treatment of chronic schizophrenic inpatients: a multicentre double‐blind comparative study

1992 • 302 citations

Psychopharmacologic Treatment of Schizophrenia

1993 • 283 citations

A prospective study of clozapine in treatment-resistant schizophrenic patients

1989 • 269 citations

Clozapine: neuroleptic-induced EPS and tardive dyskinesia

1989 • 256 citations

Dimensions of Outcome with Clozapine

1992 • 256 citations

At Issue: Defining Treatment Refractoriness in Schizophrenia

1990 • 248 citations

General Pharmacology of Clozapine

1992 • 238 citations

Clozapine: guidelines for clinical management.

1989 • 230 citations

Functional Assessment in Rehabilitation

1986 • 229 citations

Cost effectiveness of clozapine in neuroleptic-resistant schizophrenia

1993 • 211 citations

Risperidone: clinical safety and efficacy in schizophrenia.

1992 • 208 citations

A Controlled Dose Comparison of Haloperidol in Newly Admitted Schizophrenic Patients

1990 • 187 citations

When Symptoms Persist: Choosing Among Alternative Somatic Treatments for Schizophrenia

1991 • 179 citations

A Prospective, Multicenter Study of Patients' Refusal of Antipsychotic Medication

1990 • 161 citations

Neuroleptic Plasma Levels

1991 • 153 citations

Depot neuroleptic therapy: an underutilized treatment option.

1992 • 147 citations

Clinical Efficacy of Clozapine in Treatment-Refractory Schizophrenia: An Overview

1992 • 145 citations

Treatment of neuroleptic-resistant schizophrenic relapse.

1993 • 127 citations

Clozapine-Associated Agranulocytosis: Risk and Aetiology

1992 • 123 citations

Antipsychotic Drugs

1977 • 121 citations

Treatment outcome with clozapine in tardive dyskinesia, neuroleptic sensitivity, and treatment-resistant psychosis.

1987 • 119 citations

Clozapine

1991 • 110 citations

Efficacy and adverse effects of clozapine in the treatment of schizophrenia and tardive dyskinesia ? a retrospective study of 387 patients

1989 • 107 citations

Clozapine: New research on efficacy and mechanism of action

1989 • 104 citations

Fluphenazine Dose, Clinical Response, and Extrapyramidal Symptoms During Acute Treatment

1990 • 99 citations

Clozapine pharmacology and tardive dyskinesia

1989 • 65 citations

A review of clozapine: An antipsychotic for treatment-resistant schizophrenia

1990 • 48 citations

Commentary: The Strategy and Value of Neuroleptic Drug Monitoring

1985 • 42 citations

Clozapine and D₁/D₂ Antagonism in Extrapyramidal Functions

1992 • 41 citations

Novel approaches to the pharmacotherapy of schizophrenia

1986 • 36 citations

Diagnostic confusion in treatment-refractory psychotic patients.

1992 • 32 citations

The use of clozapine in treatment-refractory schizophrenia

1993 • 17 citations

Clozapine in the Treatment of Refractory Schizophrenia: Canadian Policies and Clinical Guidelines^*

1992 • 17 citations

Dosaging Patterns in Schizophrenia with Depot, Oral and Combined Neuroleptic Therapy

1993 • 13 citations

Ethical and Clinical Considerations in Selecting Patients Who Will Receive Clozapine

1990 • 11 citations

Reassessment of state hospital patients diagnosed with schizophrenia

1989 • 5 citations

Effect of atypical and typical antipsychotic drugs on neuropsychological functions in early-stage schizophrenic patients

1992 • 5 citations

Response to Fuchs

1994 • 3 citations

A pharmacoeconomic evaluation of clozapine in one patient.

1993 • 3 citations

Efficacy and tolerability of clozapine in the treatment of 425 schizophrenic patients

1991 • 3 citations

Differential effect of clozapine on psychopathology and cognitive dysfunction in treatment-resistant schizophrenics

1991 • 2 citations

Effects of clozapine on cognition in patients with schizophrenia

1991 • 1 citations