Localization of the site of oxygen radical generation inside the complex I of heart and nonsynaptic brain mammalian mitochondria.

The Biologic Clock: The Mitochondria?

1972 • 1,912 citations

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

1980 • 1,609 citations

Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals

2000 • 536 citations

Mitochondrial oxygen radical generation and leak: sites of production in states 4 and 3, organ specificity, and relation to aging and longevity.

1999 • 492 citations

Relationship between mitochondrial superoxide and hydrogen peroxide production and longevity of mammalian species

1993 • 484 citations

[57] Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria

1984 • 477 citations

Diphenyleneiodonium, an NAD(P)H Oxidase Inhibitor, also Potently Inhibits Mitochondrial Reactive Oxygen Species Production

1998 • 470 citations

Untitled

1997 • 432 citations

[6] Preparation of synaptic and nonsynaptic mitochondria from mammalian brain

1979 • 294 citations

NADH- and NADPH-dependent formation of superoxide anions by bovine heart submitochondrial particles and NADH–ubiquinone reductase preparation

1979 • 293 citations

Human Complex I deficiency: Clinical spectrum and involvement of oxygen free radicals in the pathogenicity of the defect

1998 • 220 citations

Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III

1999 • 218 citations

Sites and mechanisms responsible for the low rate of free radical production of heart mitochondria in the long-lived pigeon

1997 • 209 citations

Localization at complex I and mechanism of the higher free radical production of brain nonsynaptic mitochondria in the short-lived rat than in the longevous pigeon.

1998 • 204 citations

Hydrogen peroxide production by liver mitochondria in different species

1990 • 173 citations

H2O2 production of heart mitochondria and aging rate are slower in canaries and parakeets than in mice: sites of free radical generation and mechanisms involved

1998 • 166 citations

Biology Data Book

1975 • 157 citations

ADP-regulation of mitochondrial free radical production is different with complex I- or complex II-linked substrates: implications for the exercise paradox and brain hypermetabolism.

1997 • 151 citations

A reductant-induced oxidation mechanism for Complex I

1998 • 143 citations

NADH-ubiquinone oxidoreductase

1976 • 128 citations

Interaction of α‐Phenyl‐N‐tert‐Butyl Nitrone and Alternative Electron Acceptors with Complex I Indicates a Substrate Reduction Site Upstream from the Rotenone Binding Site

1998 • 118 citations

Quinone interaction with the respiratory chain-linked NADH dehydrogenase of beef heart mitochondria I. Juglone reductase activity

1970 • 72 citations

The Iron−Sulfur Clusters 2 and Ubisemiquinone Radicals of NADH:Ubiquinone Oxidoreductase Are Involved in Energy Coupling in Submitochondrial Particles

1997 • 69 citations

A Dual Effect of 1-Methyl-4-phenylpyridinium (MPP+)-Analogs on the Respiratory Chain of Bovine Heart Mitochondria

1997 • 42 citations

The antianginal agent ranolazine is a weak inhibitor of the respiratory Complex I, but with greater potency in broken or uncoupled than in coupled mitochondria

1995 • 37 citations

Kinetic of Superoxide Formation by Respiratory Chain NADH-Dehydrogenase of Bovine Heart Mitochondria

1983 • 30 citations

Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by ethoxyformic anhydride.

1984 • 8 citations

Deleted Work

1955 • 0 citations