Cell Hybridization: A Tool for the Study of Cell Differentiation

Hybridization of Somatic Cells

2015 • 258 citations

Pluripotent teratocarcinoma-thymus somatic cell hybrids

1976 • 216 citations

GENE EXPRESSION IN SOMATIC CELL HYBRIDS

1974 • 183 citations

Immunofluorescence analysis of the time-course of extinction, reexpression, and activation of albumin production in rat hepatoma-mouse fibroblast heterokaryons and hybrids.

1981 • 114 citations

Dedifferentiated variants of a rat hepatoma: Analysis by cell hybridization

1979 • 106 citations

Selective activation of human β - but not γ-globin gene in human fibroblast × mouse erythroleukaemia cell hybrids

1979 • 99 citations

Use of somatic cell hybrids for analysis of the differentiated state

1973 • 96 citations

Phenotypic exclusion in mouse melanoma-rat hepatoma hybrid cells: Pigment and albumin production are not reexpressed simultaneously

1978 • 71 citations

Reconstitution of cells by fusion of cell fragments

1978 • 59 citations

Teratocarcinoma × friend erythroleukemia cell hybrids resemble their pluripotent embryonal carcinoma parent

1977 • 53 citations

Expression of fetal and neonatal hepatic functions by mouse hepatoma-rat hepatoma hybrids

1979 • 52 citations

Use of somatic cell hybrids for analysis of the differentiated state.

1973 • 51 citations

Expression of a liver-specific function by mouse fibroblast nuclei transplanted into rat hepatoma cytoplasts

1979 • 51 citations

Extinction of hemoglobin inducibility in Friend erythroleukemia cells by fusion with cytoplasm of enucleated mouse neuroblastoma or fibroblast cells.

1977 • 50 citations

Epigenetic activation of phenylalanine hydroxylase in mouse erythroleukemia cells by the cytoplast of rat hepatoma cells.

1979 • 49 citations

Co-expression of differentiation markers in hybrids between friend cells and lymphoid cells and the influence of the cell shape

1980 • 48 citations

Short-lived cytoplasmic regulators of gene expression in cell cybrids

1981 • 41 citations

Fusion of embryonal carcinoma cells to fibroblast cells, cytoplasts, and karyoplasts

1979 • 40 citations

Activation of teratocarcinoma-derived hemoglobin genes in teratocarcinoma-friend cell hybrids

1978 • 38 citations

Expression of differentiated functions in hepatoma cell hybrids: Selection in glucose-free media of segregated hybrid cells which reexpress gluconeogenic enzymes

1977 • 34 citations

Phenotypic expression in cybrids derived from teratocarcinoma cells fused with myoblast cytoplasms

1979 • 26 citations

Maintenance of hemoglobin inducibility in somatic cell hybrids of tetraploid (2S) mouse erythroleukemia cells with mouse or human fibroblasts

1978 • 24 citations

Coordinate secretion of mouse alphafetoprotein, mouse albumin and rat albumin by mouse hepatoma‐rat hepatoma hybrid cells

1980 • 22 citations

Isolation and properties of amelanotic variants of a hamster melanoma

1979 • 9 citations