Tamoxifen enhances interferon-regulated gene expression in breast cancer cells.

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1984 • 6,841 citations

Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins

1994 • 5,932 citations

Endocrine Pharmacology of Antiestrogens as Antitumor Agents*

1990 • 403 citations

Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment.

1992 • 344 citations

Oestrogen-responsive human breast cancer in long term tissue culture

1975 • 339 citations

An amino acid substitution in the Drosophila hopTum-l Jak kinase causes leukemia-like hematopoietic defects.

1995 • 307 citations

Interferon therapy in cancer: from imaginon to interferon.

1986 • 189 citations

The genomic structure of the murine ICSBP gene reveals the presence of the gamma interferon-responsive element, to which an ISGF3 alpha subunit (or similar) molecule binds.

1993 • 184 citations

Regulation of the interferon-induced PKR: can viruses cope?

1995 • 176 citations

Expression of the terminal protein region of hepatitis B virus inhibits cellular responses to interferons alpha and gamma and double-stranded RNA.

1991 • 163 citations

Inhibition of interferon-inducible gene expression by adenovirus E1A proteins: block in transcriptional complex formation.

1991 • 145 citations

An Overview of the Interferon System: Signal Transduction and Mechanisms of Action

1996 • 142 citations

Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3

1995 • 139 citations

Differential ability of antiestrogens to stimulate breast cancer cell (MCF-7) growth in vivo and in vitro.

1989 • 117 citations

Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogene

1991 • 115 citations

Modulation of Interferon (IFN)-inducible Gene Expression by Retinoic Acid

1996 • 110 citations

Repression of the interferon signal transduction pathway by the adenovirus E1A oncogene.

1991 • 109 citations

Influence of tamoxifen on plasma levels of insulin-like growth factor I and insulin-like growth factor binding protein I in breast cancer patients.

1992 • 103 citations

Steroid Hormones: A Practical Approach

1989 • 100 citations

Fascination with 2-5A-Dependent RNase: A Unique Enzyme That Functions in Interferon Action*

1994 • 94 citations

Recombinant human interferon alpha increases oestrogen receptor expression in human breast cancer cells (ZR-75-1) and sensitises them to the anti-proliferative effects of tamoxifen

1987 • 88 citations

Serum sex steroid and peptide hormone concentrations, and endometrial estrogen and progestin receptor levels during administration of human leukocyte interferon

1982 • 83 citations

Inhibition of estrogen-responsive gene activation by the retinoid X receptor beta: evidence for multiple inhibitory pathways.

1993 • 79 citations

Interferon-gamma inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level.

1995 • 71 citations

Tamoxifen inhibits growth of oestrogen receptor-negative A549 cells

1994 • 67 citations

Effect of natural beta-interferon on cell proliferation and steroid receptor level in human breast cancer cells

1987 • 61 citations

Tamoxifen and its active metabolite inhibit growth of estrogen receptor-negative MDA-MB-435 cells

1995 • 46 citations

Effects of type I and II interferons on cultured human breast cells: interaction with estrogen receptors and with tamoxifen.

1989 • 42 citations

Effect of alpha-interferon, 17 beta-estradiol, and tamoxifen on estrogen receptor concentration and cell cycle kinetics of MCF 7 cells.

1990 • 40 citations

Rationale for combining tamoxifen and interferon in the treatment of advanced breast cancer

1989 • 27 citations

Differentiation-dependent activation of interferon-stimulated gene factors and transcription factor NF-kappa B in mouse embryonal carcinoma cells.

1993 • 22 citations

The cytostatic effects of α-interferon may be mediated by transforming growth factor-β

1989 • 19 citations

Establishment and characterization of UM-EC-2, a tamoxifen-sensitive, estrogen receptor-negative human endometrial carcinoma cell line

1990 • 17 citations

Non-encephalitogenic antigen-induced suppression and reversal of allergic encephalomyelitis

1975 • 14 citations

Inhibition of Estrogen-Responsive Gene Activation by the Retinoid X Receptor β: Evidence for Multiple Inhibitory Pathways

1993 • 12 citations

Interferon-inducible gene expression in HL-60 cells: effects of the state of differentiation.

1992 • 11 citations

Human recombinant interferon-?SER and tamoxifen: growth suppressive effects for the human breast carcinoma MCF-7 grown in the athymic mouse

1993 • 11 citations